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What does ATP stand for?
Adenosine triphosphate.
What are the components of ATP?
Adenine (a nitrogenous base), ribose (a five-carbon sugar), and three phosphate groups
What type of bonds connect the phosphate groups?
High-energy phosphoanhydride bonds.
Why is ATP called the “universal energy currency”?
Because it stores and releases energy in a form usable by all cells.
How is energy released from ATP?
By hydrolysis of the terminal phosphate bond:
ATP → ADP + Pi + energy
What enzyme catalyses ATP hydrolysis?
ATP hydrolase (also called ATPase).
How much energy is released per mole of ATP hydrolysed?
Approximately 30.5 kJ/mol under standard conditions.
Why is ATP hydrolysis useful to cells?
It provides small, manageable amounts of energy, reducing energy wastage and allowing controlled reactions.
How is ATP regenerated from ADP and Pi?
By condensation using energy from cellular processes:
ADP + Pi + energy → ATP
What are the main processes that synthesise ATP in cells?
Aerobic respiration: in mitochondria during oxidative phosphorylation
Anaerobic respiration: via substrate-level phosphorylation in glycolysis
Photosynthesis: photophosphorylation in chloroplasts
How does ATP provide energy for metabolic processes?
Supplies energy to drive anabolic reactions like protein and DNA synthesis
How does ATP support movement?
Provides energy for muscle contraction via myosin cross-bridge cycling and cytoskeletal movement in cells.
How is ATP used in active transport?
Powers carrier proteins to move molecules against their concentration gradient across membranes.
How does ATP aid secretion and bulk transport?
Fuels exocytosis, endocytosis, and vesicle movement in cells.
How does ATP contribute to cell signalling?
Used to phosphorylate proteins and activate enzymes in signalling pathways.
How is ATP used in bioluminescence or other specialized processes?
Provides energy for light production in some organisms and other energy-demanding cellular processes
Why is ATP suitable as an immediate energy source?
Small, soluble, and releases energy in controlled amounts without generating too much heat.
Why is ATP not stored in large amounts?
It is unstable; cells instead continuously regenerate it as needed from ADP and Pi.
How does ATP link energy-releasing and energy-requiring reactions?
Couples exergonic reactions (like respiration) with endergonic processes (like biosynthesis) via hydrolysis.