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Parasitology
the study of parasites and their relationship to their host
Symbiosis
“Living together”— close interrelationship between two different organisms for long periods of time
Phoresis
two symbionts traveling together; no physiologic or biologic dependence
Mutualism
both organisms benefit from this relationship
Commensalism
one benefits, the other is unaffected
Parasitism
one organism (parasite) benefits, one organism (host) is harmed
Ectoparasites
found on (not in) host; example: tick, mite, flea, fly
Endoparasites
found internally in host; example: hookworms in intestine
Facultative parasite
“opportunist”— not normally a parasite (does not require host to survive) but will become parasitic if opportunity arises
Obligate Parasite
all or part of the life cycle must be a parasitic relationship with host
Incidental (exotic) parasite
normal host is a different species
may not survive very long in wrong host
may survive and be highly pathogenic in wrong host
Definitive Host
harbors sexual (mature) stages of parasite; if parasite undergoes sexual reproduction, it will occur in this host
Intermediate Host
required in life cycle of parasite; parasite undergoes some development in this host
Paratenic or Transport Host
no parasite development in this host, but parasite remains alive ineffective for a normal host
sort of a parasite “fail-safe” plan to continue its existence)
Reservoir Host
a host that serves as a source for the parasite to be transmitted to the usual host
example: wild animals such as antelopes in Africa can serve as reservoir hosts for the protozoan parasite Trypanosoma brucei rhodesiense that can cause fatal cases of “sleeping sickness” in humans
Vectors
organisms that transmit parasites to a vertebrate host
Biological Vector
essential to the life cycle completion of the parasite
parasite must undergo some of its life cycle development in this vector
Mechanical Vector
vector is not required in the life cycle of parasite
vector physically transfers infective stage of parasite to new host
Zoonosis
infectious agent (parasite) that can be transmitted from animals to man
Sylvan cycle
a parasite cycles through its life cycle among wild animals normally (man gets into the cycle accidentally, usually)
Urban Cycle
a parasite cycles among domestic animals (and rats). Easy for man to get included in this cycle
Niche
tissue site in host to which a parasite will locate
some parasites are very specific— will locate to only one tissue in host
Host specificity
will depend upon the particular parasite
varies from non-specific to very host specific
Host susceptibility
parasite can establish infection before host can eliminate it
Host resistance
host eliminates before parasite can establish infection
Etiology
the cause of a disease (can involve infectious agents, genetic factors and/or environment
Pathogenesis
the process involved in the development of the disease
Infection
multiplication of organisms inhabiting the body
Disease
characterized by presence of clinical signs/symptoms
Non-pathogenic
does not cause disease in host
a commensal organism is this
Pathogen
can cause disease in host
Amastigote
kinetoplast and kinetosome above the nucleus, flagellum short and confine in pocket. cell is globular.
Promastigote
kinetoplast and kinetosome at anterior end of cell, flagellum free and lone; cell is elongated
Epimastigote
kinetoplast and kinetosome close and anterior to the nucleus; there is a short undulating membrane before the flagellum emerges at the anterior of the cell; cell is elongated
Trypomastigote
kinetoplast and kinetosome at posterior end of cell; flagellum forms an undulating membrane that runs the length of the cell and may continue free when it reaches the anterior end; cell is elongated