BLOOD AGENTS

Enoxaparin

Lovenox — Anticoagulant

Enoxaparin PO/Function/Common Use

SC — Inhibits blood clot (thrombus) formation — Deep vein thrombosis (DVT), pulmonary embolism (PE), during myocardial infarction

Enoxaparin Adverse Drug Reactions/Special Considerations

Bleeding, low blood platelets — Injection site reaction — No special considerations

Dabigatran

Pradaxa — Anticoagulant

Dabigatran PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — Deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation (AF)

Dabigatran Adverse Drug Reactions/Special Considerations

Bleeding — Nausea/vomiting, gastrointestinal bleeding — No special considerations

Apixaban

Eliquis — Anticoagulant

Apixaban PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — Deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation (AF)

Apixaban Adverse Drug Reactions/Special Considerations

Bleeding — Nausea/vomiting, gastrointestinal bleeding — No special considerations

Rivaroxaban

Xarelto — Anticoagulant

Rivaroxaban PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — Deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation (AF)

Rivaroxaban Adverse Drug Reactions/Special Considerations

Bleeding — Nausea/vomiting, gastrointestinal bleeding — No special considerations

Warfarin

Coumadin, Jantoven — Anticoagulant

Warfarin PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — Deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation (AF)

Warfarin Adverse Drug Reactions/Special Considerations

Bleeding — Nausea/vomiting, gastrointestinal bleeding — Check INR at least weekly to check for efficacy and safety

Aspirin

Ecotrin EC — Antiplatelet

Aspirin PO/Function/Common Use

PO, PR, IV — Inhibits blood clot (thrombus) formation — During and after myocardial infarction, stroke

Aspirin Adverse Drug Reactions/Special Considerations

Bleeding, low platelets; risk of anaphylaxis — Bruising, stomach upset and ulcers — Try to avoid IV formulation due to additional dangerous side effects

Aspirin-Dipyridamole

Aggrenox — Antiplatelet

Aspirin-Dipyridamole PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — During and after stroke only

Aspirin-Dipyridamole Adverse Drug Reactions/Special Considerations

Bleeding, low platelets — Headache, bruising, stomach upset and ulcers — No special considerations

Clopidogrel

Plavix — Antiplatelet (P2Y12 inhibitor)

Clopidogrel PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — During and after myocardial infarction, stroke

Clopidogrel Adverse Drug Reactions/Special Considerations

Bleeding, low platelets — Bruising — Stop 5–7 days before any surgical procedure

Prasugrel

Effient — Antiplatelet (P2Y12 inhibitor)

Prasugrel PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — During and after myocardial infarction

Prasugrel Adverse Drug Reactions/Special Considerations

Bleeding, low platelets — Bruising — Stop 5–7 days before any surgical procedure

Ticagrelor

Brilinta — Antiplatelet (P2Y12 inhibitor)

Ticagrelor PO/Function/Common Use

PO — Inhibits blood clot (thrombus) formation — During and after myocardial infarction

Ticagrelor Adverse Drug Reactions/Special Considerations

Bleeding, low platelets — Bruising, shortness of breath — Stop 3–5 days before any surgical procedure

Epoetin alfa

Epogen, Procrit — Hematopoietic agent

Epoetin alfa PO/Function/Common Use

SC — Promotes hemoglobin production — Anemia (e.g., related to chronic kidney disease, HIV-related anemia)

Epoetin alfa Adverse Drug Reactions/Special Considerations

Skin rash, severe hypertension, seizure, anaphylaxis — Injection site reaction, headache, hypertension — No special considerations