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what is the natural pacemaker of the heart?
the SA node
where is the SA node located
upper wall of the RA near the superior vena cava
what is the intrinsic firing rate of the SA node?
about 100 action potentials per min
what is the function of the AV node?
it delays electrical signal about 0.1 second so the ventricles can fill before they contract
where is the AV node located?
in the interatrial septum near the tricuspid valve
why is the AV node delay important
it allows the atria to finish contracting before the ventricles contract
what is the function of the fibrous skeleton?
it electrically insulates the atria from the ventricles making the AV node the only normal pathway for electrical signals
what is the bundle of HIS
a conduction pathway that carries electrical signals fromt he AV node down the interventricular septum
what do purkinje fibers do?
rapidly distribute electrical impulses through the ventricles causing them to contract from the apex upward
what makes pacemaker cells unique
they automatically generate action potentials and have no true resting membrane potential
which ion channels open first in pacemaker cells
funny (If) channels
what ion mainly enters through funny channels
sodium (Na+)
which calcium channels help pacemaker cells reach threshold
T-type calcium channels
which calcium channels cause rapid depolarization in pacemaker cells
L-type calcium channels
which ion is responsible for repolarization in pacemaker cells
potassium (K)
what ion causes rapid depolarization (phase 0) in contractile cardiac muscle cells
sodium (Na+)
what happens during the plateau phase (phase 2)
calcium enters the cell while potassium movements outward decreases
why is the plateau phase important
it prevents tetanus and allows the heart to relax and refill between beats
which ion causes depolarization in contractile cells
potassium (K)
what is the main difference between pacemaker and contractile cells
Pacemaker cells generate the heartbeat automatically, while contractile cells contract only after being stimulated.
what does an ECG measure
the electrical activity of the heart
what does P wave represent
atrial depolarization
what does QRS complex represent
ventricular depolarization
what electrical event is hidden within the QRS complex
atrial repolarization
what does the T wave represent
ventricular repolarization
what does the PR interval measure
the time it takes the electrical signal to travel from the atria through the AV node to the ventricles
what does the QT interval represent
the total time for ventricular depolarization and repolarization
what does the RR interval represent
one complete cardiac cycle (one heartbeat)
how do you calculate heart rate using the RR interval
heart rate = 60 / RR interval in seconds