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what are the two levels of evolutionary change?
microevolution and macroevolution
microevolution vs macroevolution
microevolution - small-scale genetic changes in populations, responds to shifting environmental circumstances
macroevolution - larger-scale, an evolution that occurs at or above the level of the species.
(micro/macroevolution) can result in speciation or the emergence of new species
macroevolution
a gradual accumulation of microevolutionary changes can result in
macroevolution
antibiotic resistance and the shift in bill size of darwin’s finches are both examples of
microevolution
includes all individuals of a single species that live together in the same place and time
population
how do bacteria become resistant to antibiotics?
when antibiotics are administered, an environment favoring bacteria that are even slightly resistant to the drug is created. the surviving bacteria reproduce, which can lead to antibiotic resistance for the next time the person is sick.
proper use of antibiotics minimizes this effect.
what is phenotypic variation among members of a population?
all differences in appearance or function that are passed from generation to generation
what is quantitative variation?
the variation of traits that can be measured (measurable phenotypes). examples: weight, height, blood pressure
when quantitative data is graphed, what represents the variation among individuals?
the width of the curve is proportional to the variation among individuals
what is a qualitative trait?
a trait that fits into discrete categories. examples: feather color, eye color
qualitative traits exist in 2+ discrete states or ___
polymorphisms
qualitative variation is described by
the percentage of each trait
qualitative traits are frequently controlled by ___, meaning they are simply-inherited traits.
one/few genes
do organisms with the same genotype always exhibit the same phenotypes?
no, organisms with the same genotype can exhibit different phenotypes. also, organisms with different genotypes can exhibit the same phenotype.
block rock pocket mice from NM have the same fur color as rock pocket mice with a MC1r mutation from AZ. they have the (same/different) genotype and the (same/different) phenotype.
different genotypes, same phenotype
when hydrangeas are grown in acidic soil, it produces blue flowers. when grown in neutral or alkaline soil, it produces pink flowers. They have the (same/different) genotype and the (same/different) phenotype.
same genotype, different phenotype
an organism’s phenotype is frequently the product of an interaction between
its genotype and its environment
why is it important to know whether phenotypic variation is caused by genetic differences, environmental factors, or an interaction between the two?
only genetically based variation is subject to evolutionary change
what are the two potential sources of genetic variation?
production of new alleles
rearrangement of existing alleles into new combinations
where do rearrangements of existing alleles result from?
larger scale changes in chromosome structure or number, or from genetic recombination (crossing over, independent assortment, random fertilizations)
why do some variations in protein-coding regions of DNA not affect phenotypes?
because they do not change the amino acid sequences of the proteins for which the genes code
how do biologists detect genetic variations?
gel electrophoresis and DNA sequencing technology
what is the field of genetics that deals with understanding the causes of genetic variation within populations?
population genetics
what does a population’s gene pool include?
the sum of all gene copies (alleles) at all gene loci in all individuals in the population.
define genotype frequencies and allele frequencies
genotype frequencies - the percentages of individuals in a population possessing each genotype
allele frequences - the relative abundances of the different alleles, can be calculated
what is an allele?
a particular version of DNA sequence at a given genomic location
for a gene locus with two alleles, there are ___ genotype frequencies, but only ___ allele frequencies
3 genotype frequencies, 2 allele frequencies
(recall punnett squares)
null models serve as ___ in experiments
theoretical reference points
a mathematical model that describes how genotype frequencies are established in sexually reproducing organisms.
Hardy-Weinberg principle
the hardy-Weinberg principle states that a population’s allele and genotype frequencies…
remain constant unless there is some type of evolutionary force acting upon them
the hardy-weinberg principle states that genetic equilibrium is possible only if
all of the following are met:
no mutations are occurring
the population is closed to migration
the population is infinite in size
all genotypes survive and reproduce equally well
individuals mate randomly with respect to genotypes
what are the 5 processes that foster microevolutionary change?
(opposite of hardy-weinberg)
mutation
gene flow
genetic drift
natural selection
nonrandom mating
a spontaneous and heritable change in DNA
mutation
if an organism has two of the same alleles for the same trait, it is
homozygous
in punnett squares, what are p and q?
p is the dominant trait, q is the recessive
for most animals, only mutations in ___ are heritable
the germ line (cell lineage that produces gametes)
what are deleterious mutations?
mutations that alter an individual’s structure, function, or behavior in harmful ways
ehlers-danlos syndrome
mutation in gene coding for collagen, a major component of the ECM. results in a disruption of collagen synthesis, resulting in loose skin, weak joints, or sudden death from the rupture of major blood vessels, the colon, or uterus
ehler’s danlos syndrome is an example of what type of mutation?
deleterious
dermatospraxis ehler-danlos (dEDS)
an inherited connective tissue disorder associated with extremely fragile skin leading to severe bruising and scarring, saggy redundant skin. stretchy skin and characteristic facial structure
what are lethal mutations?
mutations that may kill all carriers (if dominant) or homozygous (if recessive)
Huntington’s disease is an example of what kind of mutation?
lethal (dominant)
sickle cell anemia is an example of which type of mutation?
lethal (recessive)
what are neutral mutations?
mutations that are neither harmful nor helpful
neutral mutations mostly arise because of a change in the ___ position of a codon, the wobble base pair
third
what is an advantageous mutation?
a mutation that is beneficial to the individual
the movement of organisms or their gametes, or genetic variation from one population to another
gene flow
what are some examples of gene flow?
pollen spreading from plants, birds carrying acorns from one oak population to another, mammals moving from one population to another and reproducing
what is the founder effect?
an extreme example of genetic drift. when a small group splits off from the main population to find a new colony