PPT 4c Synapses

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16 Terms

1

pre-synaptic cell

The cell SENDING information (from axon)

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2

post-synaptic cell

cell receiving the signal

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3

Electrical synapse

a type of synapse in which the cells are connected by gap junctions, allowing ions (and therefore the action potential) to spread easily from cell to cell

in your heart

can go both directions

benefits: very quick transfer of AP

drawbacks: not at versatile, and only control one signal (AP).

FASTER THAN CHEMICAL

few mitochondria present

mainly only in the CNS and PNS

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4

Gap junction channels

provide a low resistance pathway for the electrical current to flow between cells

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5

Synaptic vesicles

Membrane-bounded compartments in which synthesized neurotransmitters are kept.

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6

calcium channel

a type of voltage-gated ion channel located on the axon terminal.

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7

auto receptors

receptors that respond to the released transmitter by inhibiting further synthesis and release

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8

neurotransmitters

chemical messengers that cross the synaptic gaps between neurons

ALL SYNTHESIZED in terminal axon

acts as a ligand to attach to a receptor: resulting in either the closing or opening of a channel

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9

synaptic cleft

The narrow gap that separates the presynaptic neuron from the postsynaptic cell.

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10

reuptake

a neurotransmitter's reabsorption by the sending neuron

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11

excitatory neurotransmitters

excite the next cell into firing

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12

inhibitory neurotransmitters

inhibit the next cell from firing

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13

neuromuscular junction

Synapse between motor neuron and muscle fiber.

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14

sarcomere

the cell of a muscle

actin and myosin molecules

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15

motor end plate

the flattened end of a motor neuron that transmits neural impulses to a muscle

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16

tetrodotoxin

in pufferfish [fugu] blocks nerve impulses, 1 milligram can kill an adult
- causes tingling, burning, numbness, drowsiness, paralysis
- caused by the algea the fish eat, cannot be destroyed via cooking or freezing
200/yr, 50% mortality rate
- BUT the extract may be used to treat migraines & menstrual cramps

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