1) pharm: resp

H1 receptors in

smooth muscles, endothelial cells, heart, CNS

H2 receptors in

parietal cells of stomach

histamin response

contraction of smooth msucle,

dilation of blood vessels,

inc HR,

stimulates gastric acid secretion,

itching, sneezing, rhinorrhea,

inc body secretions

H1 blockers examples

diphenhydramine,

loratadine,

cetrizine,

fexodenadine

antihistamine complications

dry mouth, constipation, dry eyes, sedation

decongestants stimulate

alpha receptors

decongestant action

reduction in inflammation of nasaal membranes

decongestants treat

rhinitis

decongestants: use cautiously in patients with

cardiac problems, glaucoma

decongestant examples

ephenylphrine,

ephedrine,

psuedoephedrine