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Flashcards covering the female reproductive system, oogenesis, follicle development, ovarian and uterine cycles, hormonal interactions, and puberty/menopause.
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Oogonia
Mitotic divisions are completed before birth.
Primary Oocytes
Begins between months 3 and 7 of fetal development, stops at prophase I.
Primary oocytes during childhood
Remain in prophase I until puberty.
First polar body
Smaller cell produced during the first meiotic division of a primary oocyte.
Secondary oocyte
Larger cell produced during the first meiotic division of a primary oocyte.
Secondary oocyte
Continues to metaphase II and then development stops until fertilization.
Fertilized ovum
Meiosis II finishes to form this and a second polar body if the secondary oocyte is fertilized.
Primordial follicles
First follicles formed in a female fetus, each contains one primary oocyte.
Primary follicles
Develop from primordial follicles as primary oocytes enlarge during childhood to puberty.
Secondary follicles
Develop from primary follicles with each containing an arrested primary oocyte.
Vesicular or Tertiary follicle
Matures from one secondary follicle about once a month; contains a secondary oocyte stopped in metaphase II.
Ovarian cycle
Monthly events associated with oocyte and follicle maturation.
Follicular phase
Follicle grows and develops.
Primordial follicle
Single layer of squamous follicular cells surrounds primary oocyte.
Primary follicle
Follicular cells become cuboidal granulosa cells.
Secondary follicle
Follicle wall thickens and granulosa cells secrete follicular fluid.
Vesicular (Tertiary) follicle
Pockets of fluid merge forming cavity called an antrum.
Ovulation stage
Ovary expels secondary oocyte and associated granulosa cells.
Corona radiata
Ovary wall and vesicular follicle rupture and expels secondary oocyte, granulosa cells around the egg are called this.
Corpus luteum
Ruptured follicle becomes endocrine organ.
Corpus albicans
Macrophages invade corpus luteum and fibroblasts lay down collagen.
Gonadotropin-releasing hormone (GnRH)
Hypothalamus releases this hormone.
Estrogen and progesterone
Stimulate female sex characteristics.
Uterine (Menstrual) Cycle
Cyclic changes in uterine endometrium.
Stratum functionalis
Outer (superficial) layer of the endometrium.
Stratum basalis
Inner (deeper) layer of the endometrium.
Menstrual phase
Uterus sheds stratum functionalis during menstruation.
Proliferative (Preovulatory) phase
New stratum functionalis develops with spiral arteries and veins.
Secretory (Post-ovulatory) phase
Stratum functionalis converted to secretory mucosa; endometrial glands secrete uterine milk.
Menarche
First menstrual bleeding.
Menopause
Stopping of menstruation for more than one year due to age.