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Disorders in the "muscular dystrophy" group have an infectious etiology.
a. True
b. False
False - muscular dtstrophies are genetic disorders
Which of the following are considered components of the "striatum"?
a. Caudate & globus pallidus
b. Caudate, putamen, & globus pallidus
c. Caudate & putamen
d. Putamen & globus pallidus
Caudate & putamen
The lateral corticospinal tract decussates in the _____________
a. Medulla
b. Internal capsule
c. Midbrain
d. Pons
e. Spinal cord
Medulla
Motor cortex output passes through the __________ cerebellar peduncle on its way to the cerebellum.
a. Middle
b. Superior
c. Inferior
Middle
Motor weakness that a multiple sclerosis patient may experience would more likely be due to which of the following?
a. UMN lesion
b. LMN lesion
c. NMJ lesion
d. Myopathy
UMN Lesion
Acute inflammatory demyelinating polyneuropathy causes motor weakness by compromising ____________
a. Upper motor neurons
b. NMJ transmission
c. Skeletal muscle
d. Lower motor neuron
LMN
The term "climbing" fibers refers to the axons _________ neurons.
a. Inferior olivary nucleus
b. Granule
c. Purkinje
d. Vestibular nuclei
e. Deep cerebellar nucleus
Infeior olivary nucleus
Lesions involving the face portion of the motor cortex would most likely causes facial weakness in the _________ portion of the _________ face.
a. Upper, ipsilateral
b. Lower, contralateral
c. Upper, contralateral
d. Lower, ipsilateral
Lower, contralateral
While a few cranial nerves only contain sensory neurons, most cranial nerves contain voluntary motor neurons. These motor neurons are _______ motor neurons.
a. Lower
b. Upper
Lower
Which of the following best describes myasthenia gravis?
a. NMJ disorder with impaired release of ACH
b. Myopathy
c. UMN lesion
d. NMJ disorder with destruction of the ACH receptor sites
NMJ disorder with destruction of the ACh receptor sites
Patients with cerebellar dysfunction would more likely have _________ tremors, and patients with Parkinson's disease would more likely have _______ tremors.
a. Resting, intention
b. Intention, intention
c. Resting, resting
d. Intention, resting
Intention, resting
Parkinson's disease is one of a number of CNS diseases that have abnormal accumulation of mis-folded proteins. Which of the following is the protein that is involved in Parkinson's disease?
a. Beta-amyloid
b. Cur cumin
c. Tau
d. Alpha-synuclein
E. Quercetin
Alpha-synuclein
Gower's sign would more likely be seen in patients with __________
a. Myopathy
b. Polyneuropathy
Myopathy
The "direct" & "indirect" basal ganglia pathways are connections between the _______ and the _______
a. Striatum, globus pallidus
b. Substantial nigra, striatum
c. Motor cortex, basal ganglia
d. Globus pallidus, thalamus
Striatum, globus pallidus
When the plantar aspect of a newborn's foot is stroked, it is normal for the toes to extend.
a. True
b. False
True - Positive Babinski sign
CNS lesion may be ruled out when UMN lesion signs are not found.
a. True
b. False
False
Which of the following would most likely cause clonus?
a. NMJ disorder
b. Myopathy
c. UMN lesion
d. LMN lesion
UMN Lesion
A 81-year old woman with a history of hypertension suddenly developed weakness in the left lower extremity. CVA involving which of the following arteries would best explain the patients neurological presentation?
a. Left ACA
b. Right PCA
c. Right MCA
d. Right ACA
e. Left PCA
f. Left MCA
Right ACA
Patients with myasthenia gravis typically have initial and predominant muscle weakness in the limbs.
a. True
b. False
False
When the examiner wants to check to see if clonus is present at the wrist, the examiner should quickly flex the patient's wrist.
a. True
b. False
False - Quickly extend
In addition to hand tremors, which of the following tremors would a Parkinson's patient also more likely have?
a. Head and voice
b. Feet and jaw
Feet & Jaw
A "wing-beating" tremor is characteristic of which of the following?
a. Parkinson's disease
b. Wilson's disease
c. Alzheimer's disease
d. Guillan-Barre Syndrome
Wilson's disease
The rubrospinal tract is a member of the lateral motor system of the spinal cord.
a. True
b. False
True
a stroke causes loss of neurons in the subthalamic nucleus which of the following would more likely result?
a. Involuntary movement
b. Slow, limited movement
Involuntary Movement
The hypertonicity that develops in Parkinson's disease is usually called ________
a. Spasticity
b. Rigidity
Rigidity
When the examiner wanted to check to see if clonus is present at the ankle, the examiner should quickly dorsiflex the patient's foot.
a. True
b. False
True
The medial longitudinal fasciculus (MLF) is involved in which of the following?
a. Tactile transmission
b. Motor control of the limbs
c. Coordination of head & eye movement
Coordination of head & eye movement
Injury to motor neurons in the PNS would likely cause _______ signs
a. Either UMN or LMN lesion
b. LMN lesion
c. UMN lesion
LMN lesion
The cerebellum is located in the ______ region of the brain
a. Infratentorial
b. Supratentorial
Infratentorial
Which of the following would be the predominant cause of weakness in patients with Polio?
a. Neuromuscular junction disorder
b. LMN lesion
c. UMN lesion
d. Myopathy
LMN lesion
Nigrostriatal tract dopamine ______ movement.
a. Facilitates
b. Restricts
Facilitates
Which of the following diseases would most likely have a pathological finding of "Lewy bodies"?
a. Multiple sclerosis
b. Amyotrophic lateral sclerosis
c. Subacute combined systems disease
d. Parkinson's disease
e. Guillan-Barre syndrome
Parkinson's disease
When basal ganglia lesion causes bradykinesia/akinesia, the output of the basal ganglia would most likely be abnormally ________
a. Deficient
b. Excessive
Excessive
positive "Babinski" sign would be indicative of which of the following?
a. Myopathy
b. LMN lesion
c. NMJ disorder
d. UMN lesion
UMN lesion
When the patient's movement lacks smoothness or accuracy when rapidly performing back-and-forth movement, the abnormality would be called ___________?
a. Dyspepsia
b. Dysphagia
c. Diplopia
d. Dysmetria
Dysmetria
Which of the following tracts provides UMN innervation to trunk & spinal muscles?
a. Lateral corticospinal, tract
b. Dorsal spinocerebellar tract
c. Rubrospinal tract
d. Fasculus gracilis
e. Vestibulospinal tract
Vestibulospinal tract
Purkinje neurons cause __________ of the neurons with which they synapse
a. Inhibition
b. Excitation
Inhibition
Lesion of motor tracts in the lateral column of the spinal cord would more likely result in which of the following below the level of the lesion?
a. Weakness with UMN lesion signs ipsilaterally
b. Weakness with LMN lesion signs ipsilaterally
c. Weakness with LMN lesion signs contralaterally
d. Weakness with UMN lesion signs contralaterally
Weakness with UMN lesion signs ipsilaterally
Finding UMN lesion signs would confirm your suspicions that your patient has a cerebellum lesion.
a. True
b. False
False
Which of the following would most likely cause fasciculations?
a. LMN lesion
b. UMN lesion
LMN Lesion
Which of the following synapse with Purkinje cells in the cerebellum?
a. Climbing fibers & parallel fibers
b. Mossy fibers & climbing fibers
c. Mossy fibers & parallel fibers
d. Climbing fibers, parallel fibers, & mossy fibers
Climbing fibers & parallel fibers
The presence of pathological reflexes should cause you to be concerned that your patient has __________.
a. Either a cerebellum or a basal ganglion lesion
b. A cerebellum lesion
c. A basal ganglia lesion
d. Corticospinal tract lesion
Corticospinal Tract Lesion
Motor dysfunction related to basal ganglia lesion would more likely affect the contralateral limbs.
a. True
b. False
True
Which of the following would most likely result from a lesion of the posterior frontal lobe?
a. Weakness
b. Involuntary movements
c. Loss of hearing
d. Loss of pain/temp & tactile sensation
e. Uncoordinated movements
Weakness
Motor deficits caused by cerebellar lesion would most likely occur in the _____ limbs:
ipsilateral or contralateral
Ipsilateral
Dopamine _________ the basal ganglia direct pathway & __________ the indirect pathway.
a. Excites, excites
b. Excites, inhibits
c. Inhibits, excites
d. Inhibits, inhibits
Excites, inhibits
Slowing gait and loss of arm swing may be aspects of the developing motor signs of Parkinson's disease.
a. True
b. False
True
Which of the following are the cerebellar cortex's output neurons?
a. Granule cells
b. Purkinje cells
c. Stellate cells
d. Golgi cells
Purkinje Cells