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Flashcards covering introductory human physiology concepts, scientific method, homeostasis, feedback loops, and primary tissue types.
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Physiology is defined as the study of __________ function and how the body works.
biological
The study of how disease or injury affects physiological processes is known as __________.
Pathophysiology
Comparative physiology studies the differences and similarities in the functions of __________ and vertebrates.
invertebrates
In the scientific method, several verified hypotheses may become a general __________ based on reproducible data.
theory
Research on pharmaceuticals begins by studying the effects of a chemical on cells __________, meaning in a culture dish.
in vitro
Animal studies are conducted to see if chemical effects occur __________, meaning in a living creature.
in vivo
Phase __________ clinical trials test a drug on healthy human volunteers to test for side effects and dosage.
I
Phase __________ clinical trials test a drug’s effectiveness on people with a particular disease.
II
Phase III clinical trials are conducted on a large number of people to include both sexes, many age groups, and ethnicities before approval by the __________.
FDA
In the 17th century, __________ demonstrated that the heart pumps through a closed system of vessels.
William Harvey
Claude Bernard observed that the internal environment, or __________, stays relatively constant.
milieu intérieur
The term "homeostasis" was coined in 1932 by __________ to describe the internal consistency of the body.
Walter Cannon
Homeostasis is accomplished most often by __________ feedback loops.
negative
The three components of a negative feedback loop are the receptors (sensors), the __________, and the effector.
integrating center
Body temperature sensors in the brain detect deviation from the set point of __________.
37∘C
Maintaining conditions within a certain normal range, or __________, is often achieved through antagonistic effectors.
dynamic constancy
The normal range for arterial blood pH is __________.
7.35–7.45
The normal fasting blood value for glucose is __________.
70–99mg/100mL
In __________ feedback, the action amplifies the changes that stimulated the effectors.
positive
Regulation is __________ when cells within an organ sense a change and signal to neighboring cells to respond.
intrinsically
The __________ system regulates organs by releasing hormones into the blood.
endocrine
The basic unit of structure and function of living things is the __________.
cell
The three types of muscle tissue are skeletal, cardiac, and __________.
smooth
Skeletal muscle fibers are formed by the union of separate cells called __________ to form a syncytium.
myoblasts
Cardiac muscle cells are interconnected physically and electrically by __________.
intercalated discs
The coordinated, wave-like contraction of smooth muscle layers is called __________.
peristalsis
Nerve tissue is composed of neurons and supporting cells called __________.
neuroglia
The three parts of a neuron are the cell body, dendrites, and the __________.
axon
Epithelial membranes that are only one layer thick are called __________ epithelium.
simple
Epithelial cells that are as tall as they are long are classified as __________.
cuboidal
Simple __________ epithelium, found in the wall of the small intestine, allows for absorption.
columnar
Epithelial membranes are attached to underlying connective tissues by a __________.
basement membrane
Exocrine glands secrete into __________ that transport secretions to the surface of the epithelial membrane.
ducts
Glands that lack ducts and secrete hormones into capillaries are called __________ glands.
endocrine
Connective tissue is characterized by an __________ made up of protein fibers, extracellular material, and specialized cells.
extracellular matrix
The major cells of connective tissue proper that produce and secrete the extracellular matrix are called __________.
fibroblasts
Cartilage is composed of cells called __________.
chondrocytes
In bone, cells called __________ trap mineral salts to form lamellae.
osteoblasts
The three embryonic germ layers from which specialized cells arise are endoderm, mesoderm, and __________.
ectoderm
Zygotes are __________, meaning they can become any type of cell.
totipotent
Adult stem cells are __________, as they can become several related cells but are limited to a narrow range.
multipotent
The __________ fluid compartment contains 65% of total body water.
intracellular