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Prokaryotic cell
A cell without a nucleus or membrane-bound organelles
Eukaryotic cell
A cell with a true nucleus and membrane-bound organelles
Prokaryote vs. eukaryote DNA
Prokaryotic DNA is circular and free in the cytoplasm; eukaryotic DNA is linear and stored in the nucleus
Prokaryote vs. eukaryote size
Prokaryotic cells are generally smaller than eukaryotic cells
Prokaryote vs. eukaryote ribosomes
Prokaryotes have smaller (70S) ribosomes; eukaryotes have larger (80S) ribosomes
Cell Theory
All living things are made of cells, cells are the basic unit of life, and all cells come from pre-existing cells
Universal cell features
All cells have a plasma membrane, cytoplasm, DNA, and ribosomes
Organelle
A specialized structure within a cell that performs a specific function
Subcellular structures
Non-membrane structures like ribosomes, cytoskeleton, and centrioles
Nucleus
Contains DNA in eukaryotic cells and controls gene expression
Nuclear envelope
Double membrane that encloses the nucleus and contains nuclear pores
Nucleolus
Dense region inside the nucleus where ribosomal RNA is produced
Ribosomes
Sites of protein synthesis; can be free in the cytoplasm or bound to rough ER
Rough endoplasmic reticulum
Produces proteins for membranes or secretion; covered in ribosomes
Smooth endoplasmic reticulum
Synthesizes lipids, metabolizes carbohydrates, detoxifies drugs
Golgi apparatus
Modifies, sorts, and packages proteins and lipids for delivery
Vesicles
Small membrane-bound sacs that transport substances within or outside the cell
Lysosomes
Contain digestive enzymes to break down waste and damaged organelles
Peroxisomes
Break down fatty acids and detoxify harmful substances
Plasma membrane
A selective barrier that controls what enters and exits the cell
Mitochondria
Produce ATP through cellular respiration; contain their own DNA
Chloroplasts
Sites of photosynthesis in plant cells; contain their own DNA
Cytoskeleton
A network of fibers that provides structure, movement, and transport inside the cell
Microtubules
Thick hollow tubes that help maintain cell shape and form the spindle during division
Microfilaments
Thin strands of actin involved in cell movement and muscle contraction
Intermediate filaments
Provide mechanical support and help anchor organelles in place
Centrosome
Microtubule-organizing center that includes centrioles in animal cells
Cilia and flagella
Extensions of the cell that aid in movement; built from microtubules
Endomembrane system
A group of membranes and organelles that work together to modify, package, and transport lipids and proteins
Organelles in the endomembrane system
Nuclear envelope, rough and smooth ER, Golgi apparatus, lysosomes, vesicles, and plasma membrane
Membrane flow
Movement of membrane and contents between endomembrane system components via vesicles
Organelles not in the endomembrane system
Mitochondria, chloroplasts, peroxisomes, and the cytoskeleton
Mitochondria and chloroplasts origin
Believed to have originated from free-living prokaryotes via endosymbiosis
Function of the nucleus
Stores genetic material and controls cell activities through gene expression
Function of ribosomes
Translate mRNA into proteins
Function of the ER
Smooth ER makes lipids and detoxifies; rough ER processes and folds proteins
Function of the Golgi apparatus
Receives proteins from ER, modifies them, and sends them to their destinations
Function of lysosomes
Digest macromolecules, recycle damaged organelles
Function of peroxisomes
Break down fatty acids and neutralize toxic compounds
Function of mitochondria
Produce ATP through aerobic respiration
Function of chloroplasts
Capture light energy to make glucose through photosynthesis
Function of cytoskeleton
Maintains cell shape, enables intracellular transport, and supports cell movement
Genetic information flow
DNA → RNA → Protein
Transcription
Occurs in the nucleus; DNA is used to make mRNA
Translation
Occurs at ribosomes; mRNA is used to assemble amino acids into a polypeptide