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What percent of a person's body weight is water?
50-70%
Where does the water in our bodies come from?
food, drink, and a byproduct of metabolism
Minimum amount of water for a human a day?
2.5L/day or 2500 mL
Intake: metabolism
250 mL (10%)
Intake: food
750 mL (30%)
Intake: liquids
1500 mL (60%)
Output: sweat
200 mL (8%)
Output: feces
100 mL (4%)
Output: skin and lungs
700 mL(28%)
Output: urine
1500 mL(60%)
The fluids in the body are what?
solutions
The liquid that dissolves the solute?
solvent
The substances dissolved in a solvent?
solute
Electrolytes
minerals that naturally carry a positive or negative electric charge
What is the function of electrolytes?
regulate fluid distribution, blood pH, muscle contractions, and nerve signaling
How are electrolytes obtained?
food and drink
What is the role of the kidneys with electrolytes?
filtering out excess electrolytes for excretion in the urine
What are the main electrolytes?
sodium, chloride, potassium, magnesium, and calcium
Fluid composition: intracellular
2/3
Fluid composition: extracellular
1/3
What are bodily fluids composed of?
water, electrolytes, and other dissolved substances such as sugar, fats and proteins
How are electrical and chemical gradients created between intracellular and extracellular fluid?
different concentrations of electrolytes in the intracellular and extracellular fluid
What determines where water will move via osmosis and is involved in creating action potentials in nerves and muscles?
the electrolyte gradients
Tonicity
a measure of solute concentration across a membrane
Hypotonic
less solute concentration in extracellular fluid than intracellular fluid - cell will expand
Isotonic
same solute concentration in extracellular fluid and intracellular fluid
Hypertonic
higher solute concentration in extracellular fluid that intracellular fluid - cell will shrink
At the arterial end of a capillary, what is the pressure and movement?
hydrostatic pressure forces fluid in capillary to be filtered into the interstitial fluid
At the venous end of a capillary, what is the pressure and movement?
capillary solute concentration is higher than the surrounding fluid, which pulls water into the vessel
What is the main electrolyte involved in maintaining fluid volume and blood pressure
sodium (Na+)
What is the culprit for many electrolyte imbalances?
kidney disease
What are the main imbalances associated with poor kidney function?
hyperkalemia and hyponatremia
What does prolonged or excessive vomiting lead to?
excess loss of water and electrolytes
Can excessive vomiting cause hypo or hypernatremia?
both
Dehydration
fluid loss excedes fluid intake
What can happen with dehydration?
blood can become more concentrated - and blood pressure can drop
How can someone become dehyrated?
heavy exercise or high environmental temps
Who is most at risk for dehydration?
elderly and infants
How can patients with hypertension be helped?
reducing sodium intake
How does reducing sodium intake help people with hypertension?
does not treat but can lower blood pressure
How does increasing potassium help with hypertension?
can act to relax blood vessels and aid in balancing sodium