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Infectious organism trigger an inflammatory response that are attacked by ___ then….
Macrophages, Lymphocytes
What do Lymphocytes effectively recognized?
A specific foreign molecule
Antigens
any molecule including a response from a lymphocytes
What are the main classes of lymphocytes?
B-lymphocytes & T-lymphocytes
Cytotoxic T lymphocytes
attack foregin cells directly
Cytotoxic T lymphocytes bind to…
antigen-bearing cells to bring a foreign pathogen to the lymphocyte
What does Cytotoxic T lymphocytes signal cells to?
undergo apoptosis to programmed cell death
What does Cytotoxic T lymphocytes destroy?
virus-infected cells & some cancer cells
B Lymphocytes become what?
plasma cells
What does the plasma cells secrete?
antibodies
Why do plasma cells mark cells?
the destruction by macrophages
What does B lymphocytes respond primarily to?
Bacteria & Bacterial Toxins
Natural Killer (NK) cells
do not recognize specific antigens
Where do the lymphocytes originate?
Bone marrow
Where do the T lymphocytes sometimes travel to?
Thymus gland
Where do B lymphocytes sometimes travel to?
Bone marrow
What are activated lymphocytes are able to recognize?
unique antigen (foreign)
Activated lymphocyte travel through bloodstream to…
meet & bind to a specific antigen
During activation, Lymphocyte is presented its antigen by
Macrophage or Dendritic Cell
Effector Lymphocytes
respond immediately, then die
Memory Cells
wait until the body encounters the antigen again
basis of acquired immunity
prevent subsequent infections of the same illness