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Boyle’s Law: Pressure and volume are inversely related. As lung volume increases, pressure decreases, and vice versa.
Rib cage: Protects thoracic organs, expands/contracts during breathing.
Trachea: Connects larynx to lungs; airway conduit.
Bronchial Tree: Branches into bronchi and bronchioles, ending in alveoli.
Lungs: Elastic organs responsible for gas exchange.
Pleurae: Visceral (lung surface) and parietal (chest wall) pleura.
Intrapleural Space: Thin fluid-filled space; maintains negative pressure.
Physiology: Prevents lung collapse, allows lungs to expand with thoracic wall.
Pneumothorax: Air enters intrapleural space, causing lung collapse.
Muscles of Breathing: Alter size/pressure of thoracic cavity.
Inhalation: Diaphragm contracts, rib cage expands.
Exhalation: Muscles relax or contract (forced) to reduce lung volume.
Diaphragm: Dome-shaped muscle; main driver of tidal inhalation.
Pressure Differences:
Inhalation: Atmospheric pressure > alveolar pressure.
Exhalation: Alveolar pressure > atmospheric pressure.
Tidal (Passive): Uses diaphragm.
Forced: Engages accessory muscles (e.g., intercostals, neck, chest).
Tidal: Passive elastic recoil.
Forced: Uses accessory muscles (abdominal, internal intercostals).
Tidal Breathing Cycle: Inhalation (active) ~40%; exhalation (passive) ~60%.
Lung Volumes vs. Capacities:
Volumes: Tidal, inspiratory reserve, expiratory reserve, residual.
Capacities: Vital, total lung, inspiratory, functional residual.
Spirometry: Graphs volumes/capacities; vital capacity = IRV + TV + ERV.
Developmental Changes: VC increases with age and body growth.
Life vs. Speech Breathing:
Life: Nose, 40/60 inhale/exhale, passive.
Speech: Mouth, 10/90 inhale/exhale, active.
Recoil Forces: Passive return of lungs/rib cage to rest post-inhalation.
Resting Expiratory Level: Balance point of lung recoil and thoracic expansion.
Lung Disease Types:
Obstructive: Narrowed airways (e.g., asthma, COPD).
Restrictive: Reduced lung expansion (e.g., fibrosis).
Symptoms:
Dyspnea: Shortness of breath.
Stridor: High-pitched, wheezing sound on inspiration.
Phonation
Source-Filter Independence: Source (vocal folds) operates separately from filter (vocal tract).
Phonation: Process of vocal fold vibration producing sound.
Laryngeal Anatomy:
Cartilages:
Unpaired: Thyroid, cricoid, epiglottis.
Paired: Arytenoids, corniculates, cuneiforms.
Bone: Hyoid (not part of larynx but supports it).
Abduction: Vocal folds apart (breathing).
Adduction: Vocal folds together (phonation).
Regions:
Glottal: Space between vocal folds.
Supraglottal: Above folds (resonance).
Subglottal: Below folds (pressure buildup).
Extrinsic Muscles: Elevate or depress larynx.
Intrinsic Muscles:
Adduction: Lateral cricoarytenoid, interarytenoids.
Abduction: Posterior cricoarytenoid.
Tension: Cricothyroid (lengthens), thyroarytenoid (shortens).
Histology of Vocal Folds:
Epithelium: Outer layer.
Lamina Propria: Superficial (gel-like), intermediate (elastic), deep (collagen).
Thyroarytenoid: Muscle forming body of fold.
Theories of Phonation
Myoelastic Aerodynamic Theory: Vocal fold vibration is due to muscle elasticity and aerodynamic forces.
Bernoulli Effect: Increased airflow = decreased pressure; helps folds close.
Pressure Relationships:
Subglottal pressure must exceed supraglottal for vibration.
Vibration Cycle:
Folds close → pressure builds → folds open → air escapes → folds pulled back.
Phasing:
Vertical: Inferior to superior fold closure.
Anterior-Posterior: Middle to edges.
Acoustic Features of Phonation
Quasi-periodic Wave: Regular but not perfectly periodic.
Complex Wave: Multiple frequencies.
Glottal Spectrum: Shows harmonics; falls in amplitude at higher frequencies.
Fundamental Frequency (F0): Controlled by vocal fold length, mass, tension.
Intensity: Controlled by subglottal pressure and medial compression.
Cover-Body Model
Cover: Epithelium + superficial lamina propria.
Body: Thyroarytenoid muscle.
Importance: Explains vibratory properties of vocal folds.
Articulation and Resonance
Valves: Lips, tongue, velum, vocal folds.
Consonants vs. Vowels:
Consonants: Obstructed airflow.
Vowels: Open vocal tract.
Consonant Classification: Place (e.g., bilabial), manner (e.g., stop), voicing.
Vowel Classification: Tongue height and advancement.
Source-Filter Theory:
Source (glottal), Filter (vocal tract).
Laryngeal Source: Periodic sound with harmonic structure.
Supraglottal Resonance:
Transfer function = effect of vocal tract on source.
Acts as filter; length/shape change = formant shifts.
Vocal tract = closed tube; odd-number multiple resonance.
Formants: F1 (height), F2 (advancement), lip rounding lowers F2.
Vowel Production and Perception
Differences:
Vowels: Periodic, open tract.
Consonants: Various sources (periodic/aperiodic).
Vowel Acoustics: