UNCLASSIFIED ANTIDYSRHYTHMIC DRUGS/ DRUG THERAPY IN EMERGENCY RESUSCITATION OF ADULTS/ MAGNESIUM SULFATE

What is the action of Adenosine (Adenocard)?

Acts like a calcium channel blocker, slows conduction through the AV node, interrupts reentry pathways through the AV node, and restores normal sinus rhythm in paroxysmal supraventricular tachycardia (PSVT).

Which condition is Adenosine effective for?

Adenosine is effective for SVT involving the AV node.

What is some key points about the administration of Adenosine?

It must be given as a rapid IV bolus; central line preferred; if pushed slowly = ineffective, Transient asystole may occur (normal)

What are some side effects of Adenosine?

Flushing, chest pain, shortness of breath, bronchospasm, transient bradycardia, asystole, and feeling of impending doom.

What is the action of Magnesium Sulfate?

Regulates Na⁺, K⁺, and Ca²⁺ flow across cardiac cell membranes and stabilizes excitable membranes.

In what situation is Magnesium Sulfate indicated?

It is used for torsades de pointes and if hypomagnesemia is contributing to dysrhythmias.

What is a notable side effect of Magnesium Sulfate during rapid infusion?

Hypotension.

What is the first-line medication for adults in asystole or pulseless rhythms during resuscitation?

Epinephrine.

What adverse effect can high doses of Epinephrine cause?

Lactic acidosis.

What is Atropine used for?

Symptomatic bradycardia.

What does Sodium Bicarbonate treat in emergency situations?

Hyperkalemia and tricyclic antidepressant (TCA) overdose.

When is Lidocaine indicated?

For VT/VF during arrest and may continue post

When is Calcium Chloride indicated in?

Hypercalcemia with cardiac arrest; calcium channel blocker overdose.