BIOL 4680 Pathophysiology: Cell Injury and Accidental Cell Death

Vocabulary flashcards covering key terms and definitions related to cell injury and death in pathophysiology.

Cell Injury

The damage to a cell caused by various factors leading to impaired cell function.

Necrosis

A type of cell death characterized by the uncontrolled breakdown of cells.

Pathophysiology

The study of the functional changes that accompany a particular syndrome or disease.

Ischemia

Inadequate blood supply to an organ or part of the body.

Oxidative Stress

An imbalance between the production of reactive oxygen species and the body's ability to detoxify them.

Reversible Injury

Cellular damage that can be repaired, restoring normal function.

Mitochondrial Dysfunction

Abnormal function of mitochondria resulting in decreased ATP synthesis.

Apoptosis

Controlled cell death that is a normal part of growth and development.

Evidence of Cell Injury

Signs and symptoms indicating cellular damage, such as pain or changes in blood composition.

Lipid Peroxidation

The oxidative degradation of lipids, leading to cell membrane damage.

Reactive Oxygen Species (ROS)

Highly reactive molecules derived from oxygen that can damage cellular components.

Etiology

The study of the cause of disease.

Pathogenesis

The mechanism of development of a disease.

Hypoxia

Inadequate supply of oxygen to tissues.

Chronic Inflammation

A prolonged inflammatory response that can lead to tissue damage and disease.

Ferroptosis

A form of cell death characterized by iron-dependent lipid peroxidation.

Homeostasis

The maintenance of stable internal conditions in an organism.