Module 6 quiz questions

Is pathogenesis a single protein or toxin?

No, pathogenesis is a qualitative term that encompasses the entire disease development process.

How is LD50 used in assessing the virulence of a pathogen?

LD50 indicates the amount of the pathogen required to cause death in half of the exposed animals.

Which bacterial strain is considered more virulent based on the given LD50 values?

Strain B.

Who is best known for the germ theory of disease?

Louis Pasteur.

What is the second postulate developed by Koch?

The microorganism must be grown in pure culture.

Which of the following is an example of an obligate intracellular pathogen?

Chlamydiae.

Which of the following is an example of a facultative intracellular pathogen?

Mycobacterium tuberculosis.

What is the purpose of including positive and negative controls in PCR-based detection?

To avoid false results and ensure accuracy.

Which method provides quantitative results in pathogen detection?

Real-Time PCR (qPCR).

What can ELISA be used to recognize in patients?

Antibody titer.

What happens to other proteins present in the sample during the ELISA workflow?

They are washed off because they do not bind to the antibody.

How does Porphyromonas gingivalis contribute to microbial dysbiosis and inflammation?

By overgrowth and changes in the oral microbiota.

What is the main characteristic of keystone pathogens in a healthy microbiota?

They modulate the host immune response and alter the environment.