collagen vascular diseases

2 categories of collagen diseases

genetic or autoimmune

inherited CT disorders

Marfan syndrome, Ehlers-Danlos syndrome, Osteogenesis imperfecta

autoimmune CT disorders

systemic Lupus, Sclerodema, Sjogrens syndrome, Polymyositis or Dermatomyositis

what is marfan sydrome

autosomal dominant, affects cardiovascular system, abnormally tall with long appendages, pectus excavatum

treatment of marfan sydrome

beta blockers, echocardiograms, avoid vigorous physical exertion

physical therapy for marfan syndrome

isokinetic activity at an aerobic pace, keep hr below 110, no sudden or isometric movements

what is ehlers danlos syndrome

inherited collagen mutation, involves skin/joint/vascular system, causes chronic musculoskeletal pain and arthritis

physical therapy for ehlers danlos

joint protection and stability, injury prevention, motor skill training

what is systemic lupus

autoimmune, affects many organ systems, most common and serious

Symptoms of systemic lupus

kidney disease, neurological disease, photosensitivity, arthritis, discoid rash

treatment of systemic lupus

immunosuppression, plaquentil

physical therapy for systemic lupus

reduce pain, inflammation, and stiffness

isometric exercise with inflammation

isotonic exercise in absence of inflammation

what is scleroderma

increased collagen deposition, fibrosis of skin and internal organs, 80% CREST syndrome, 20% diffuse

diffuse scleroderma

skin hardening of entire body, raynauds phenomenon, hardening of internal organs

treatment of scleroderma

calcium channel blockers, ACE inhibitors, steroids

physical therapy for scleroderma

wax bath, heat, stretching, hand therapy, mouth ROM

what is Sjogrens disease

autoimmune, dysfunction of lacrimal and salivary glands, dry eyes and mouth

treatment of Sjogrens sydrome

artificial tears, sugar free gums, steroids

physical therapy for Sjogrens syndrome

speech therapy, reduce deconditioning and fatigue

what is polymyositis and dermatomyositis

autoimmune, inflammatory disease of muscle fibers, muscle weakness, dermato when skin also involved

diagnosis of polymyositis and dermatomyositis

muscle enzyme testing, MRI, muscle biopsy

treatment of polymyositis and dermatomyositis

steroids, immunosuppressants

physical therapy for polymyositis and dermatomyositis

strengthen distal muscles, reduce fall risk, aerobic and resistance training