25.2-25.4 – MMR, RSV, Coronavirus, Rabies

name the diseases covered by the MMR vaccine

• measles (rubeola)

• mumps

• rubella

describe mumps

swelling of parotid glands, mostly in children <15

describe RSV

respiratory syncytial virus; contagious that affects children under 2 but seen more in adults that had covid

is RSV in the MMR vaccine?

no

alt name for rubella

german measles

rubella/german measles

milder than measles but teratogenic, STORCH test to see if you have immunity

is the MMR vaccine given during pregnancy?

no, it’s attenuated

alt name for rubeola

measles

rubeola/measles

highly contagious, epidemic, causes organ failure

• Koplik’s spots

Koplik’s spots

white spots on the soft tissues on the upper respiratory tract that point to measles

describe the structure of coronaviruses

enveloped and non-segmented virus (doesnt change too much)

three zoonotic strains

• SARS-Cov

• MERS-CoV

• SARS-CoV-2

what is the covid pathogen?

SARS-CoV-2/coronavirus

what is the covid disease?

Covid-19

course of SARS/COVID disease

envelope binds to proteins we have called ACE2 (on nearly all our cells) and will infect the entire organ it’s attached to

proteins on nearly all our cells that are involved in metabolic processes and are infected by sars-cov-2

ACE2

hypersensitivity that causes long covid

type 4

• t cells CD8

treatment for covid

remdesivir, paxlovid (antiviral drugs)

azithromycin (antibiotics)

preventative vaccinations for coronavirus

protein based (Novavax) - viral spike vaccine]

vector based (J&J janssen) - viral spike DNA

RNA based (moderna, pfizer) - viral spike mRNA