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What makes up the basic structure of a neuron?
cell body (soma), dendrites, an axon, and axon terminals
What does the soma contain?
nucleus and organelles supporting cell functions
Does the soma have a specific shape or does the shape vary?
the shape of the soma varies
Which part of a neuron's basic structure has a chemically excitable membrane and also receives input from other neurons and glia?
soma
What is the Greek word for body?
soma
What greek word means tree?
dendron
True or False: dendrites are only smooth.
False. Dendrites may be smooth or have spines
Which basic structure of a neuron is structurally similar to the somatic membrane?
dendrites
Which basic structure of a neuron conducts electrical potentials in a non-propagated, decremental fashion?
dendrites
What basic structure of a neuron has a membrane that is designed to conduct incoming info to the soma and is also chemically excitable?
dendrites
What is the greek word meaning axis?
axon
What basic structure conducts info (action potential) away from the soma?
axon
Why is the axon structurally different from soma and dendrites?
because the axon was designed to conduct action potentials w/o any change in magnitude
What is axonal transport?
moves proteins from soma to bouton and recycled materials back to soma
True or false: Dynein: anterograde transport
False. Dynein: retrograde transport and Kinesin: anterograde transport
What basic structure does not appear on all neurons and also has an electronically excitable membrane?
axon
Will there ever be more than one axon?
no IF there is an axon, there will only be one
What are axon branches called?
collaterals
What happens when an axon gets near its target?
it branches extensively- terminal branches (teledendria or terminal branches)
Where do terminal branches end?
in bouton or terminal endings
Where is the terminal bouton located?
at the end of a teledendron
What are bouton en passant?
varicosities along the length of the teledendron prior to terminal bouton
What do we use to categorize and name neurons?
shape, function, w/ or w/o myelin, and orientation & projections
What are the different shapes of the soma?
pyramidal cell, stellate cell, and granule cell
What conducts info to the CNS?
sensory (afferent)
What conducts info away from CNS?
motor (efferent)
What processes info between afferents and efferents?
interneurons (intermuncials)
What form circuits between close neurons?
local neurons
What interconnect local interneurons in different in different regions of the CNS?
relay neurons
What is the greek word meaning glue?
glia
What is another term for glia?
neuroglia
What are the 3 types of glia in the CNS?
astrocytes (astroglia), microglia, and oligodendrocytes (oligodendroglia)
What is the one type of glia in the PNS?
schwann cells (neurolemma)
What are astrocytes shaped like?
stars
What do astrocytes provide?
psychological support (nutrients/waste) and physical support
True of false: astrocytes isolate synapses and interact dynamically with neurons
true
Which type of glia forms scar tissue following an injury?
astrocytes
What type of glia are small cells that are derived from blood and are part of the immune system attacking microorganisms w/in the brain?
microglia
Which type of glia proliferate migrate to area of injury or where microorganisms are located w/in CNS?
microglia
What does phagocytic mean?
removes debri/waste
Which type of glia wraps around axons (not all axons, but most) and forms myelin?
oligodendria
True or false: myelin = segmented envelopment of axons
true
What are the small gaps between insulated segments of an axon called?
Nodes of Ranvier
Which type of glia has processes that extend to a series of nearby axons?
oligodendroglia
Which type of glia is only seen during the development of the CNS?
radial glia
Which type of glia ensheath all Peripheral Nervous System axons and sometimes gives rise to myelin?
schwann cells
True or false: each neurolemma cell extends a limited distance along associated axons
true
What type of glia is associated with myelin?
schwann cells
True or false: all schwann cells have myelinated axons?
false - not all axons are myelinated (a.k.a. nonmyelinated axons)
If the schwann cells' axon is myelinated what are between myelin cells?
Nodes of Ranvier
Which type of glia is a response to axon injury?
schwann cells
What is damaged in the CNS when microglia move in to clear damaged/dead tissue and astrocytes move in to form a glial scar blocking regeneration?
axons
What does it mean when myelin "disappears" temporarily, and schwann cells become phagocytic as well as actas guiding tubes for regenerating axons?
there was axon damage in the Peripheral NS
What is another way to describe reactive synaptogenesis?
axon sprouting
What is the process being described below?
When a nucleus is partially denervated, remaining inputs often will expand their synaptic surface area and sprouting additional bouton.
reactive synaptogenesis
What are the 2 parts that make up the Peripheral NS?
somatic NS and autonomic NS
What are the 2 parts that the somatic NS can be broken down into?
afferent (sensory) and efferent (motor)
What are the 2 parts that the autonomic NS can be broken down into?
sympathetic NS and parasympathetic NS
What are 2 parts that make up the CNS?
brain and spinal cord
What are the 3 basic subdivisions of the peripheral NS?
cranial nerves, spinal nerves, and autonomic NS
What is the term for a collection or bundle of axons found in the Peripheral NS?
nerve
What is the term for a collection or bundle of axons found in the CNS?
tract
What is the term for optic nerve or basal ganglia?
misnomer
What is the term for a collection of somas/dendrites in the Peripheral NS?
ganglion
What is the term for a collection of somas/dendrites in the CNS?
nucleus
How many cranial nerves are there?
12
What are cranial nerves?
nerves that connect directly to the brain
Name all 12 cranial nerves.
olfactory nerve, optic nerve, oculomotor nerve, trochlear nerve, trigeminal nerve, abducens nerve, facial nerve, auditory nerve, glossopharyngeal nerve, vagus nerve, spinal accessory nerve, and hypoglossal nerve
Which cranial nerves are afferent?
olfactory nerve, optic nerve, trigeminal nerve, facial nerve, auditory nerve, glossopharyngeal nerve, and vagus nerve
Which cranial nerves are efferent?
oculomotor nerve, trochlear nerve, trigeminal nerve, abducens nerve, facial nerve, glossopharyngeal nerve, vagus nerve, spinal accessory nerve, hypoglossal nerve
Which nerve runs from the retina of the eye to the optic chiasma where axons from both retinas co-mingle?
optic nerve
Which nerve innervates all but 2 muscles in the eye and also supplies involuntary parasympathetic intrinsic eye muscle (iris and ciliary body)?
oculomotor nerve
Which nerve controls eye movement?
trochlear nerve
Which nerve is the largest cranial nerve and supplies sensory info from the head?
trigeminal nerve
Which nerve receives sensory info from mouth, teeth, nasal cavity, cornea, dura mater, and anterior 2/3 of tongue (NOT TASTE)?
trigeminal nerve
What is tic doloroux
intractable facial pain
Which nerve affects eye movement?
abducens nerve
What is the sensory part of the facial nerve?
taste from anterior 2/3 of tongue
What is the motor part of the facial nerve?
muscles of facial expressions and some salivary and lacrimal glands
What are some other term for auditory nerve?
vestibulocochlear, stato-acoustic, and acoustic nerve
Which nerve attaches to the medulla?
glossopharyngeal nerve
What is the sensory part of the glossopharyngeal nerve?
taste from posterior 1/3 of tongue
Which nerve controls gag reflex?
glossopharyngeal nerve
What are some other terms for vagus nerve?
gypsy or wanderer
Which nerve arises from the medulla?
vagus nerve
Which nerve joins the vagus nerve innervating the thoracic and abdominal viscera?
spinal accessory nerve
Which nerve supplies striate muscles of larynx and pharynx, as well as supplies trapezius and sternocleidomastoid?
spinal accessory nerve
Which nerve arises from the medulla?
hypoglossal nerve
Which nerve supplies muscles of tongue and neck, and carries proprioceptive?
hypoglossal nerve
What are the following 4 points describing?
1. cranial nerves attach at irregular intervals
2. 2 cranial nerves aren't nerves, but projections of CNS (I and II)
3. cranial nerves lack dorsal and ventral roots creating variation in efferent and afferent components
4. some cranial nerves have more than one ganglion, some have none
the differences between cranial nerves and spinal nerves
What protects the spinal cord?
vertebrae
How many pairs of spinal nerves are there?
31
How are the 31 pairs of spinal nerves labeled?
by sequence and level where they enter/exit vertebral column
What are mixed nerves?
nerves that are both afferent and efferent
True or false: in the spinal cord, grey matter --> axons
false
grey matter--> somas/dendrites & white matter--> axons
How many spinal nerves are cervical (C1 is between skull and 1st cervical vertebrae)?
8
How many spinal nerves are thoracic?
12
How many spinal nerves are lumbar?
5
How many spinal nerves are sacral?
5
How many spinal nerves are coccygeal?
1