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What is homeostasis?
regulation of the internal conditions of a cell or organism to maintain optimum conditions
What conditions are controlled in the human body? (3)
blood glucose concentration
body temperature
water levels
What two types of responses happen in the body to control conditions?
nervous responses or chemical responses
What three parts are present in all control systems?
receptors
coordination centres
effectors
In the body control system: what do cells called receptors do?
detect stimuli
In the body control system: what do coordination centres do?
receive and process information from receptors
Give examples of coordination centres in the human body (3)
the brain
spinal cord
pancreas
In the body control system: what do effectors do?
bring about responses which restore optimum levels (of things like glucose and water)
Give examples of effectors in the human body (2)
muscles
glands
What is the nervous system?
the body system that includes all of the nerve cells, the brain and the spinal cord
What does the nervous system do?
allows humans to react to their surroundings and to coordinate their behaviour
What is the central nervous system? (2)
the brain
spinal cord
What does the central nervous system do?
it coordinates the response of effectors (which may be muscles contracting or glands secreting hormones)
What is the name given to the part of the nervous system which contains only nerves?
The peripheral nervous system
What happens in the body between a stimulus and a response?
stimulus → receptor → coordinator → effector → response
What is a stimulus?
A change in external environment
What is a reflex action?
An automatic and rapid nervous response which does not require the conscious part of the brain
What does a sensory neurone do?
it transmits electrical impulses from receptors in the sense organs to the CNS
What does a synapse relay neurone do?
it transmits electrical impulses from sensory neurones to motor neurones
What does a motor neurone do?
it carries electrical impulses from the CNS to effectors such as muscles or glands
What is the function of the cerebral cortex? (2)
Controls intelligence, personality and conscious thought
Controls high-level functions, such as language and verbal memory
What is the function of the cerebellum?
Controls balance, co-ordination of movement and muscular activity
What is the function of the medulla?
Controls unconscious activities such as heart rate and breathing rate
What are some of the difficulties of investigating and treating brain function? (2)
The brain is complex and delicate
Treatments such as surgergy can pose huge risks
How can we produce images of the brain?
Using MRI (magnetic resonance imaging) scanning
How does the eye focus on near objects? (3)
the ciliary muscles contract
the suspensory ligaments loosen
the lens is then thicker and refracts light rays strongly
How does the eye focus on far objects? (3)
the ciliary muscles relax
the suspensory ligaments are pulled tight
the lens is then pulled thin and only slightly refracts light rays
How does the eye adapt to dim light? (3)
radial muscles of iris contract
circular muscles of iris relax
pupil dilates
How does the eye adapt to bright light? (3)
radial muscles of the iris relax
circular muscles of the iris contract
pupil constricts
What are the two types of light receptors?
Rods and cones
What is the function of the cornea in the eye?
Refracts light - bends it as it enters the eye

What is the function of the iris in the eye?
Controls how much light enters the pupil

What is the function of the lens in the eye?
Further refracts light to focus it onto the retina

What is the function of the retina in the eye?
Contains the light receptors

What is the function of the optic nerve in the eye?
Carries impulses between the eye and the brain

What is the function of the sclera in the eye? (2)
Tough white outer layer of the eye
It helps protect the eye from injury
What is the scientic name for short sightedness?
Myopia
What is the scientic name for long sightedness?
Hyperopia
Which part of the brain controls body temperature?
The thermoregulatory centre
How is temperature controlled when the body is too cold? (3)
Blood vessels constrict (vasoconstriction)
sweating stops
skeletal muscles contract (shiver)
How is temperature controlled when the body is too hot? (2)
Blood vessels dilate (vasodilation)
sweat is produced from the sweat glands
What is the endocrine system?
the body system that includes hormones and glands
What does the endocrine system do?
sends hormones around the body through the blood
What are hormones produced by?
glands
What are hormones? (2)
chemicals which are carried in the bloodstream
They cause effects to happen in organs
Which is faster: the nervous system or the hormonal (endocrine) system?
the nervous system
Which effects last longer: the nervous system or the hormonal (endocrine) system?
the endocrine system
What does the pituitary gland do? (2)
Produces many hormones which regulate body conditions
Some of these hormones act on other glands, which produce other hormones
Where is the pituitary gland?
At the base of the brain
Where is the pancreas?
Behind the stomach
Where is the thyroid?
Along the front of the windpipe
Where are the adrenal glands?
One above each kidney
Where are the ovaries?
In the lower abdomen
Where are the testes?
In the scrotum
Where is blood glucose concentration monitored?
In the pancreas
What is carbohydrate broken down into?
Glucose
What happens when blood glucose levels are too high? (2)
the pancreas produces the hormone insulin that causes glucose to move from the blood into the cells
In liver and muscle cells excess glucose is converted to glycogen for storage
What is type 1 diabetes?
the pancreas fails to produce sufficient insulin, so blood glucose can reach dangerously high levels
How is type 1 diabetes controlled and treated?
with insulin injections
What is type 2 diabetes?
the body cells no longer respond to insulin produced by the pancreas
How can type 2 diabetes be controlled? (2)
carbohydrate controlled diet
exercise regime
Which type of diabetes is obesity a risk factor for?
Type 2 diabetes
[𝐇𝐢𝐠𝐡𝐞𝐫] What happens when blood glucose levels are too low?
the pancreas produces the hormone glucagon that causes glycogen to be converted into glucose and released into the blood
[𝐇𝐢𝐠𝐡𝐞𝐫] What is negative feedback? (3)
Receptors detect stimuli, like high levels of a hormone
The coordination centre organises a response and the effector produces a response which counteracts the change
The optimum level is restored
How does water leave the body? (3)
Exhalation
urine
sweat
How do ions leave the body? (2)
Urine
sweat
Why is water balance important?
If body cells lose or gain too much water by osmosis they do not function efficiently
What happens to the excess amino acids from the digestion of protein? (2)
In the liver these amino acids are deaminated to form ammonia
It is then converted to urea for excretion
What does ADH stand for?
anti-diuretic hormone
Where is ADH produced?
The pituitary gland
When does the release of ADH increase?
When the body has too little water
When does the release of ADH decrease?
When the body has too much water
What happens when the production of ADH increases?
More water reabsorbed by nephrons and urine is more concentrated
What happens when the production of ADH decreases?
Less water reabsorbed by nephrons and urine is more dilute
How can kidney failure be treated? (2)
Kidney transplant
dialysis
What happens at puberty?
reproductive hormones cause secondary sex characteristics to develop
What are the main male and female reproductive hormones? (2)
Male - testosterone
Female - oestrogen (Oestrogen and testosterone are produced by both sexes)
What is the main role of testosterone?
it stimulates sperm production
Where is oestrogen produced?
In the ovaries
Where is testosterone produced?
In the testes
What four hormones control the menstrual cycle?
FSH, LH, oestrogen and progesterone
What do FSH and LH stand for? (2)
Follicule-stimulating hormone
Luteinising hormone
How many days long is the menstrual cycle (usually)?
28
What is the function of FSH?
causes maturation of an egg in the ovary
What is the function of LH?
stimulates the release of an egg
Which hormones are involved in maintaining the uterus lining?
Oestrogen and progesterone
[𝐇𝐢𝐠𝐡𝐞𝐫] How does oestrogen interact with FSH and LH in the menstrual cycle? (2)
Stimulates release of LH
Inhibits release of FSH (negative feedback)
[𝐇𝐢𝐠𝐡𝐞𝐫] How does progesterone interact with FSH and LH in the menstrual cycle?
Inhibits release of both LH and FSH (negative feedback)
What is contraception?
hormonal and non-hormonal methods of controlling fertility
List hormonal methods of contraception (5)
Oral contraceptive pills
Patch
Implant
Injection
The IUD (intrauterine device, or the coil)
List barrier methods of contraception. (2)
Condoms
Diaphragms
How do oral contraceptives control fertility?
they contain hormones to inhibit FSH production so that no eggs mature
How do injections, implants or skin patches control fertility?
they slowly release progesterone to inhibit the maturation and release of eggs for a number of months or years
How do barrier methods control fertility?
they prevent the sperm reaching an egg
How do intrauterine devices control fertility?
they prevent the implantation of an embryo or release a hormone
How do spermicidal agents control fertility?
they kill or disable sperm
How does abstaining from intercourse control fertility?
this tries to make sure there are no sperm in the female reproductive system when an egg may be in the oviduct
How do surgical methods control fertility?
they prevent the sperm reaching an egg by removing tubes in the reproductive systems
What does sterilisation involve?
The falllopian tubes (which connect the ovaries to the uterus) or the sperm duct (the tube between the testes and penis) are cut or tied
[𝐇𝐢𝐠𝐡𝐞𝐫] Give two ways that hormones are used to treat infertility (2)
Fertility drugs
IVF