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Vocabulary flashcards covering bone tissue, bone structure, joints, muscles, and energy systems from the lecture notes.
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Osseous tissue
Another name for bone tissue; a living, rigid connective tissue that forms bones and remodels with stress.
Bone tissue
Specialized connective tissue that makes up the bones of the skeletal system; dynamic and living.
Organic components of bone
Approximately 30% of bone; includes collagen fibers, proteins, and bone cells that provide flexibility and strength.
Inorganic components of bone
Approximately 70% of bone; mainly calcium and phosphate (hydroxyapatite) that give hardness and durability.
Hydroxyapatite
Calcium phosphate crystals that provide bone hardness and rigidity.
Collagen fibers
Organic component contributing to bone flexibility and tensile strength.
Osteoblasts
Bone-forming cells that synthesize collagen and minerals to build new bone.
Osteocytes
Mature bone cells that maintain bone tissue and communicate with other bone cells.
Osteoclasts
Bone-resorbing cells that break down bone to release minerals like calcium.
Bone remodeling
Continuous renewal of bone through a balance of bone formation (osteoblasts) and resorption (osteoclasts).
Ossification
Bone formation process; converting connective tissue or cartilage into bone.
Intramembranous ossification
Direct bone formation forming flat bones (skull, mandible, clavicles) from mesenchyme.
Endochondral ossification
Bone formation from a cartilage model; forms most bones, including long bones.
Epiphyseal plate
Growth plate; cartilage layer at the ends of long bones where lengthwise growth occurs.
Periosteum
Tough outer membrane covering bone; contains osteoblasts and blood vessels. Acts as attachment for tendons/ligaments.
Endosteum
Thin membrane lining the inner surface of bone, including the medullary cavity.
Compact bone
Dense, hard outer layer of bone containing osteons and providing strength.
Spongy bone
Lightweight inner bone tissue containing trabeculae and red bone marrow.
Osteon (Haversian system)
Structural unit of compact bone containing a central canal and concentric lamellae.
Haversian canal
Central channel within an osteon that contains blood vessels and nerves.
Lamellae
Concentric rings of bone tissue around the Haversian canal.
Lacunae
Small cavities that house osteocytes within bone tissue.
Canaliculi
Tiny channels connecting lacunae to allow nutrient and waste exchange between osteocytes.
Trabeculae
Thin, crisscrossing plates in spongy bone that help absorb load and house red marrow.
Red bone marrow
Marrow in spongy bone that produces red blood cells, white blood cells, and platelets.
Yellow bone marrow
Marrow in the medullary cavity that stores fat (lipids) for energy.
Hematopoiesis
Production of blood cells, primarily in red bone marrow.
Calcium homeostasis
Maintenance of stable calcium levels in the blood, involving bone storage/release and kidney/intestine handling.
Parathyroid hormone
Hormone that increases blood calcium by stimulating bone resorption and calcium reabsorption in the kidneys.
Activation of vitamin D (calcitriol)
Process that increases intestinal calcium absorption, supporting calcium balance.
Macroscopic structure of bone
Visible bone structure including periosteum, compact bone, and marrow spaces.
Periosteum functions
Protects/nourishes bone, houses osteoblasts, attaches tendons/ligaments, and contains vessels and nerves.
Articular cartilage
Hyaline cartilage covering joint surfaces to reduce friction and absorb shock.
Epiphysis
End of a long bone where growth occurs and spongy bone typically resides.
Diaphysis
Central shaft of a long bone; primarily compact bone.
Medullary (marrow) cavity
Central cavity within diaphysis that contains yellow bone marrow in adults.
Nutrient foramen
Small opening in bone allowing blood vessels to enter and nourish the bone.
Joint (articulation)
Location where two or more bones meet; allows movement and provides stability.
Fibrous joints
Joints connected by fibrous tissue with little or no movement; include sutures, syndesmoses, gomphoses.
Sutures
Fibrous joints between skull bones with minimal movement.
Syndesmoses
Fibrous joints with longer connective tissue allowing limited movement (e.g., tibia-fibula).
Gomphoses
Fibrous joints where a peg-like fit occurs, such as teeth in the jaw.
Cartilaginous joints
Joints linked by cartilage with limited movement; include synchondroses and symphyses.
Synchondroses
Cartilaginous joints united by hyaline cartilage (growth plates).
Symphyses
Cartilaginous joints joined by fibrocartilage (e.g., intervertebral discs).
Synovial joints
Freely movable joints with a synovial cavity, articular cartilage, and a capsule reinforced by ligaments.
Synovial cavity
Fluid-filled space in a synovial joint allowing movement.
Planar (gliding) joint
Flat surfaces slide past one another; example: carpal joints.
Hinge joint
Joint allowing flexion/extension like elbow.
Pivot joint
Joint allowing rotation around a single axis, e.g., neck rotation.
Condyloid joint
Joint with an oval articular surface allowing movement in two planes; example: knuckles.
Saddle joint
Joint with saddle-shaped surfaces allowing movements in two planes; example: thumb base.
Ball-and-socket joint
Multiaxial joint allowing a wide range of motion in all directions (e.g., shoulder).
Synarthrosis
Immovable joint.
Amphiarthrosis
Slightly movable joint.
Diarthrosis
Freely movable synovial joint.
Skeletal muscle
Voluntary muscle attached to bones that contracts to create movement.
Tendon
Connects muscle to bone, transmitting muscle force.
Epimysium
Outer connective tissue sheath surrounding a whole muscle.
Perimysium
Connective tissue around muscle fascicles (bundles of fibers).
Endomysium
Connective tissue surrounding individual muscle fibers.
Sarcolemma
Plasma membrane of a muscle fiber.
Sarcoplasm
Cytoplasm of a muscle fiber.
Myofibril
Long, thread-like structure inside muscle fibers containing contractile proteins.
Sarcomere
Functional unit of a muscle fiber; region between two Z-lines where contraction occurs.
Actin
Thin filament protein involved in contraction.
Myosin
Thick filament motor protein that pulls actin during contraction.
Troponin
Regulatory protein that binds calcium and moves tropomyosin to expose actin sites.
Tropomyosin
Regulatory protein that blocks/ exposes myosin binding sites on actin depending on calcium.
Calcium ions (Ca2+)
Ions released from the sarcoplasmic reticulum to enable contraction by binding to troponin.
ATP
Adenosine triphosphate; main energy currency driving cross-bridge cycling.
Cross-bridge
Myosin head bound to actin forming a connection that enables filament sliding.
Sliding filament theory
Model describing how actin and myosin filaments slide past each other to shorten a sarcomere.
Neuromuscular junction (NMJ)
Synapse where a motor neuron communicates with a muscle fiber to stimulate contraction.
Acetylcholine (ACh)
Neurotransmitter released at NMJ to trigger muscle fiber depolarization.
Acetylcholinesterase (AChE)
Enzyme that breaks down ACh in the synaptic cleft to stop stimulation.
Motor neuron
Nerve cell that transmits signals from the CNS to muscles.
Excitation-contraction coupling
Process linking an electrical signal (action potential) to muscle contraction via Ca2+ release.
Sarcoplasmic reticulum (SR)
Organelle in muscle cells that stores and releases Ca2+ during contraction.
Calcium release from SR
Ca2+ release triggered by the action potential to initiate contraction.
ACh at NMJ
Acetylcholine released into the synaptic cleft to activate the muscle cell.
Energy systems in muscle activity
Three systems supply ATP: ATP-PC (phosphagen), anaerobic glycolysis, and aerobic respiration.
ATP-PC system (phosphagen system)
Immediate energy system using ATP and creatine phosphate for short, high-intensity efforts.
Creatine phosphate (CP)
High-energy phosphate donor that regenerates ATP from ADP in the ATP-PC system.
Creatine kinase
Enzyme that catalyzes the regeneration of ATP from ADP using CP.
Anaerobic glycolysis
Glucose breakdown without oxygen producing ATP and lactate; lasts ~30 seconds to 2 minutes.
Glycogenolysis
Breakdown of glycogen to glucose to fuel glycolysis.
Glycolysis
Glucose conversion to pyruvate in the cytoplasm, yielding ATP; can produce lactate without oxygen.
Lactate (lactic acid)
Byproduct of anaerobic glycolysis; contributes to muscle fatigue.
Aerobic energy system
Most sustainable energy system using oxygen; fuels prolonged, low-to-moderate activity.
Krebs cycle (Citric Acid Cycle)
Oxidation of acetyl-CoA in mitochondria generating NADH/FADH2 for ATP production.
Electron transport chain (ETC)
Series of proteins in mitochondria that produce large amounts of ATP using NADH/FADH2 and oxygen.
Fat as fuel
Fatty acids are a primary fuel during long-duration, low-to-m moderate-intensity activity.
Type I fibers
Slow-twitch muscle fibers; high endurance, fatigue-resistant.
Type II fibers
Fast-twitch muscle fibers; high force output but fatigue more quickly.
Motor unit
A motor neuron and all the muscle fibers it innervates.
Agonist (prime mover)
Muscle that actively contracts to create a movement.
Antagonist
Muscle that relaxes to allow the movement; can slow or stop motion.
Synergist
Muscle that assists the agonist in performing a movement.
Fixator
Muscle that stabilizes a joint to enable efficient movement.