[TOXICOLOGY] MANOR

PROVERBS 16;3

B) Clinical toxicology

1. A specialized field of toxicology that designates an area of professional emphasis within the realm of medical science
   a. Forensic toxicology c. Environmental toxicology
   b. Clinical toxicology d. Regulatory toxicology

C) descriptive toxicology

2. This is an area of toxicology which is concerned directly with toxicity testing, which provide necessary information for safety evaluation and regulatory requirements.
   a. mechanistic toxicology c. descriptive toxicology
   b. regulatory toxicology d. forensic toxicology

A) fatal dose

3. The quantity of medicine that can kill an organism
   a. fatal dose b. LD50 c. Teratology d. Threshold Limit Value

C) taking several small doses at long intervals

4. Acute poisoning includes, except:
   a. taking a strong poison c. taking several small doses at long intervals
   b. taking several small doses but frequent d. taking excessive single doses

C) Post-Mortem evidence

5. This is obtained from an examination of the tissues and organs of the dead.
   a. Experimental evidence c. Post-Mortem evidence
   b. Chemical evidence d. Circumstantial evidence

C) due to interference with the enzyme system utilizing it

6. Death may result from poisoning due to the following causes, except:
   a. due to interference with the carriage of oxygen
   b. due to inhibition of the respiratory movements by neuromuscular agents
   c. due to interference with the enzyme system utilizing it
   d. circulatory failure as a result of cardiac glucosides

D) all of the above

7. Catharsis as a way of removing a poison includes, except:
   a. increases intestinal injury when a corrosive is ingested
   b. is avoided in a patient showing disturbed electrolyte imbalance
   c. hypertonic cathartic and enemas are hazardous in the presence of impaired renal function
   d. all of the above

B) castor oil

8. This is recommended in phenol poisoning as a cathartic but is contraindicated in poisoning by chlorinated insecticide, since it may increase intestinal absorption
   a. magnesium sulfate b. castor oil c. mannitol d. Fleet's Phospho-soda

B) cumulative poison

9. A poison which increases suddenly in its intensity of action after slow or gradual addition of it is
   a. corrosive poison b. cumulative poison c. true poison d. irritant poison

B) the aspiration of the poison into the respiratory tract

10. The most serious potential consequence of ingestion of liquid hydrocarbon such as kerosene or gasoline is:
    a. paralysis of the peristaltic motion of the GI tract
    b. the aspiration of the poison into the respiratory tract
    c. destruction of body enzymes by the poison

B) normal saline

11. The specific antidote for the treatment of poisoning due to oral ingestion of silver nitrate would be the oral administration of:
    a. acetic acid solution b. normal saline c. sodium bicarbonate

C) 8th cranial damage

12. Streptomycin can cause:
    a. 4th cranial damage b. 7th cranial damage c. 8th cranial damage d. 6th cranial damage

E) salicylate analgesics

13. Most accidental poisoning in children is caused by:
    a. detergents b. bleaches c. crayons d. insecticides e. salicylate analgesics

B) starch

14. Antidote for iodine poisoning:
    a. silver nitrate b. starch c. potassium nitrate d. sugar

A) lung

15. The evidences to be saved in nonfatal poisoning are the following, except:
    a. lung b. urine c. food d. blood e. body fat

D) public health officer

16. When reporting cases of poisoning like eating in public restaurant, the cases should be reported to the:
    a. nurse b. family doctor c. pharmacist d. public health officer e. BFAD

A) blood

17. The major routes by which toxic agents gain access to the body are through the ff. except:
    a. blood b. GIT c. lungs d. skin e. parenteral route

C) 4

18. Acute exposure by inhalation refers to continuous exposure for less than 2 hours, most frequently for:
    a. 2 b. 3 c. 4 d. 5 e. 6 hrs.

A) atropine

19. Dryness of the mouth is a side effect of
    a. atropine b. aspirin c. acetaminophen d. cimetidine

A) Ca

20. One group of thiol-containing enzymes that may play a critical role in cell injury and death as a result of oxidative inactivation (oxidative stress) is:
    a. Ca b. Na c. K d. Mg e. A1 transportation Alpase

A) hydrolysis

21. The ff. are mechanisms of poison absorption, except:
    a. hydrolysis b. endocytosis c. filtration d. passive diffusion

D) all of the above

22. An example of a Phase 1 Reaction in the metabolism of substances is/are:
    a. oxidation b. hydrolysis c. reduction d. all of the above

A) gastric lavage

23. Pneumomediastenum is a complication of the use of:
    a. gastric lavage b. hemodialysis c. hemoperfusion d. emetics

C) laxative

24. Constipation caused by active charcoal can be relieved by concomitant administration of
    a. glycerol b. water c. laxative d. none of the above

D) none of the above

25. Contraindication to the use of cathartics are the ff. except:
    a. GI hemorrhage b. corrosive agents c. renal failure d. none of the above

C) 100%

26. The percentage of oxygen which is indicated for carbon dioxide poisoning to increase the conversion of carboxyhemogloblin to hemogloblin and myoglobin and to increase oxygen saturation of the plasma is:
    a. 50% b. 75% c. 100% d. 10%

C) acetone

27. Nail polish remover contain
    a. aniline b. ammonium hydroxide c. acetone d. phosphoric acid

C) strychnine

28. Convulsions caused by drug poisoning are most commonly associated with:
    a. Phenobarbital b. diazepam c. strychnine d. chlorpromazine

A) ASA and barbiturates

29. Alkalinizing the urine with sodium bicarbonate is useful in the treatment of poisoning with:
    a. ASA and barbiturates b. phencyclidine c. amphetamines d. morphine

D) methanol

30. Activated charcoal may be used in the treatment of these poisoning, except:
    a. Phenobarbital b. propoxyphene c. aspirin d. methanol

D) treatment with 100% carbon dioxide is effective

31. These statements regarding carbon monoxide poisoning are true, except:
    a. the oxygen carrying capacity of the blood is decreased
    b. the oxyhemoglobin dissociation curve becomes shifted to the left, releasing less oxygen to the tissues
    c. a carboxyhemoglobin level of less than 30% produces minimal symptoms
    d. treatment with 100% carbon dioxide is effective

D) tetracyclines

32. Ototoxicity may be an adverse reaction of the following, except:
    a. streptomycin b. ethacrynic acid c. furosemide d. tetracyclines

D) tetracyclines

33. Individuals who are deficient in glucose-6-dehydrogenase experience hemolysis following the treatment with these drugs, except:
    a. dapsone b. ethacrynic acid c. primaquine d. tetracyclines

B) enflurane

34. Acute intermittent porphyria is an absolute contraindication to the use of:
    a. nitrous oxide b. enflurane c. ketamine d. thiopental sodium

A) halothane

35. Direct hepatotoxicity has been observed with the following anesthetics agents:
    a. halothane b. nitrous oxide c. thiopental d. all of the above

A) MAO inhibitor

36. A patient has resulted in acute hypertensive crisis after eating cheese. This interaction is possible if the patient is on:
    a. MAO inhibitor b. aspirin c. tetracyclines d. all of the above

A) bismuth

37. It is used in the manufacture of smoke bomb, antiseborrheic shampoos, in the treatment of bone fracture and rickets.
    a. bismuth b. boron c. cadmium d. cesium e. chromium

E) chromium

38. Its deficiency mimics diabetes mellitus, it is found in brown sugar and butter
    a. bismuth b. boron c. cadmium d. cesium e. chromium

A) bismuth

39. It is used in silvering of mirror and it causes metal line gum.
    a. bismuth b. boron c. cadmium d. cesium e. chromium

C) oxalate

40. It is the poison found in rust and ink eradicator.
    a. nitrite b. naphthalene c. oxalate d. lead e. mercury

A) nitrite

41. It is used to preserve the color of meat in pickling.
    a. nitrite b. naphthalene c. oxalate d. lead e. mercury.

E) mercury

42. It is used in fingerprint photography
    a. nitrite b. naphthalene c. oxalate d. lead e. mercury.

D) arsenic

43. It is the choice of professional poisoners.
    a. nitrite b. naphthalene c. oxalate d. arsenic e. berrylium

E) berrylium

44. It is the most toxic metal.
    a. nitrite b. naphthalene c. oxalate d. arsenic e. berrylium

E) formaldehyde

45. Ammonium salt is the antidote for
    a. aniline b. cyanide c. ethyl alcohol d. iodine e. formaldehyde

A) aniline

46. Methylene blue is the antidote for
    a. aniline b. cyanide c. ethyl alcohol d. iodine e. formaldehyde

B) cyanide

47. It is known as the prussic acid
    a. aniline b. cyanide c. ethyl alcohol d. iodine e. formaldehyde

C) ethyl alcohol

48. It is known as the Neutral spirit
    a. aniline b. cyanide c. ethyl alcohol d. iodine e. formaldehyde

A) hydrogen sulfide

49. It is also known as the stink damp
    a. hydrogen sulfide b. carbon monoxide c. carbon disulfide d. nitrogen oxide

B) phosphorus

50. It is known as the rodent poison
    a. hydrogen sulfide d. carbon tetrachloride
    b. phosphorus e. carbon monoxide
    c. carbon disulfide

D) ethanol

51. The abuse of this drug is responsible for major medical and socio-economic problems:
    a. chloral hydrate b. chloral hydrate and ethanol c. nitrous oxide d. ethanol

B) atropine

52. Poisoning due to anticholinesterase is the best managed by the administration of:
    a. theophylline b. atropine c. salbutamol d. ethanol

B) sulfur dioxide

53. Conjuctival and bronchial irritation are primary signs of exposure to:
    a. ergot b. sulfur dioxide c. ethyl alcohol d. mercury

A) iron

54. Deferoxamine is an antidote for:
    a. iron b. methanol c. calcium d. iodine

A) ethyl alcohol

55. These are simple asphyxiants which are gases, except:
    a. ethyl alcohol b. methane c. nitrogen d. none of these

A) sourine

56. Toxic substance found in "tulingan" tuna and:
    a. sourine b. nenerupin c. gemblid d. potassium bromate

C) antivenin and suction and tourniquet

57. Effective therapy to rattle snake bite:
    a. suction and tourniquet b. antivenin c. antivenin and suction and tourniquet d. none of these

B) sulfuric acid

58. A type of poison that causes blackening and severe corrosion in the mouth:
    a. nitric acid b. sulfuric acid c. phenol d. hydrochloric acid

D) mercury

59. It causes the Minamata disease:
    a. Nickel b. manganese c. molybdenum d. mercury

D) nicotine

60. Examples of herbicides, except:
    a. phenoxyacetic acid b. paraquat c. diquat d. nicotine

C) Amanita phalloides

61. Mushroom poisoning comes from:
    a. belladonna b. digitalis c. Amanita phalloides d. all of these

C) naphthalene

62. It is the poison in toilet bowl deodorant:
    a. Nitrite b. lead c. naphthalene d. oxalate

B) BAL with EDTA

63. Lead can be effectively detoxified by:
    a. barium sulfate b. BAL with EDTA c. ethanol d. deferroxamine

A) ethanol

64. An antidote to methanol poisoning:
    a. ethanol b. digoxin c. atropine d. naloxone

A) Syrup of ipecac

65. Induction of vomiting is accomplished by administering:
    a. Syrup of ipecac b.Ginger ale c.Peppermint syrup d.None of these

C) potassium bromate

66. Banned toxic substance in "pandesal", cakes and other bakery products:
    a. gemblid b. venrupin c. potassium bromate d. sourine

B) 5 grams

67. Fatal dose of aspirin:
    a. 5 grains b. 5 grams c. 5 mg d. all of these

B) hallucinations and dilated pupil

68 Lysergic acid poisoning has this toxic syndrome/s:.
a. dilated pupil b. hallucinations and dilated pupil c. hallucinations d. none of these

D) exhaustion of respiratory center

69. Death due to strychnine poisoning is from:
    a. fatigue c. cardiac failure
    b. fatigue of respiratory muscle d. exhaustion of respiratory center

B) lead oxide

70. Litharge is also known as:
    a. magnesium oxide b. lead oxide c. arsenic trioxide d. nitrous oxide

B) cassava

71. Manihot toxin is found in this crop root:
    a. yam b. cassava c. sweet potatoes d. none of these

C) barbiturate

72. Best known physiological antidote for strychnine:
    a. codeine b. pilocarpine c. barbiturate d. morphine

C) coma with open eyes and violent syndrome

73. Phencyclidine has this toxic syndrome:
    a. violent syndrome c. coma with open eyes and violent syndrome
    b. coma with open eyes d. none of these

A) ciguatoxin

74. Poisonous fishes contain unedible organs or toxins such as:
    a. ciguatoxin b. saxitoxin c. aflatoxin d. scombroid

A) aromatic compound

75. Activated charcoal is specifically helpful in the treatment of poisoning from:
    a. aromatic compound b. all of these c. alkaloid d. none of these

B) strychnine

76. Convulsions caused by drug poisoning are commonly associated with:
    a. diazepam b. strychnine c. phenobarbital d. chlorpromazine

C) aflatoxin

77. A carcinogenic substance found in stale peanut:
    a. peroxide b. glyceryl ester c. aflatoxin d. fatty acid

B) lactrotoxin

78. Black widow spider venom is called:
    a. neostigmine b. lactrotoxin c. carbachol d. all of these

D) barbiturate

79. The antidote for DDT poisoning:
    a. adrenaline b. atropine c. amphetamine d. barbiturate

C) barium

80. Causes digitalis-like toxicity and baritosis:
    a. antimony b. aluminum c. barium d. arsenic

B) copper

81. Metal used in water purification:
    a. lead b. copper c. gold d. gallium

B) cyanide

82. Bitter almond odor is symptoms of this poisoning:
    a. mercury b. cyanide c. lead d. none of these

D) bloody stool and hematemesis

83. Paraquat poisoning is characterized by:
    a. bloody stool b. none of these c. hematemesis d. bloody stool and hematemesis

C) magnesium hydroxide

84. The universal antidote usually contains tannic acid, activated charcoal and:
    a. calcium hydroxide b. aluminum hydroxide c. magnesium hydroxide d. all of these

C) picrotoxin

85. A poisonous principle of Coalculus indicus used as fish poison:
    a. Phenacetin b. picric acid c. picrotoxin d. colchicines

D) emetine

86. Principal active alkaloid of ipecac:
    a. caffeine b. apomorphine c. ergonovine d. emetine

C) acetone

87. Sweet odor of vomitus is/are due to this type of poison/s:
    a. chloroform and acetone b. turpentine c. acetone d. chloroform

A) it is amphoteric and coats the stomach

88. A common household substance given as antidote is milk because:
    a. it is amphoteric and coats the stomach b. coats the stomach c. it is amphoteric d. nota

A) dinoflagellates

89. It causes shellfish toxicity:
    a. dinoflagellates b. snails c. jellyfish d. octopus

B) dimercaprol

90. Treatment of bismuth poisoning involves the use of:
    a. morphine b. dimercaprol c. EDTA d. none of these

C) seizures

91. Side effects frequently seen with benzodiazepines, except:
    a. ataxia b. drowsiness c. seizures d. none of these

D) tetrodotoxin

92. Most commonly known animal poison:
    a. scombroid b. venom c. saxitoxin d. tetrodotoxin

B) pyrethrum

93. A botanical insecticide:
    a. malthion b. pyrethrum c. parathrion d. none of these

A) hyaluronidase

94. An enzyme found in the snake venom is:
    a. hyaluronidase b. urease c. steapsin d. ptyalin

A) local toxicity

95. The effects that occurs at the site of the first contact between the biological system and the toxicant.
    a. local toxicity b. economic toxicity c. systemic toxicity d. cumulative toxicity

A) local toxicity

96. The effects that occur at the site of the first contact between the biological system and the toxicant.
    a. local toxicity b. economic toxicity c. systemic toxicity d. cumulative toxicity

B) naphthalene

97. One of the ingredients in mothballs
    a. oxalic acid b. naphthalene c. activated charcoal d. arsenic e. none of these

C) both a and b

98. Poison that converts the red hemoglobin to chocolate brown color
    a. aniline b. nitrobenzene c. both a and b d. ether

A) sulfuric acid

99. Dilution with water is contraindicated in the poisoning with
    a. sulfuric acid b. acetic acid c. hydrochloric acid d. none of the above

A) cresol

100. The poisonous substance in Lysol:
     a. cresol b. phenol c. resorcinol d. thymol