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what is formed by a glomerulus and its capsule?
renal corpuscle
what is a nephron?
functional unit of the kidney
running from the glomerular capsule to the tip of the mudullary pyramid.. seriies of ducts that together make
renal tubule
renal pyraminds make up the layer called the renal
renal medulla
renal artery→ segmentaal arteries→ __ arteries → arcuate arteries
interlobar
convoluted tobule
proximal and distal
a nephron consists of what two parts?
renal corpuscle and renal tubule
what section of the nephron loop are permeable to water?
thin
what are the two componenets of the renal corpuscle
glomerulus/ glomerular capsule
renal tubule contains…
PCT, nephron loop, DCT, collecting duct
the renal medulla is comprised of…
renal pyramids
what renal tubule segments runs from the nephron loop to the collecting duct?
distal convoluted tubule
what is the longest and most coiled region of the renal tubule
PCT
what has an ascending limb and descending limb?
nephron loop
which nephrons have long nephron loops that extend deep into the medulla?
juxtamedullary nephrons
where does the collecting ducts get fluid from?
DCT
neres + ganglia serving the kidney
renal plexus
fluid in the glomerular capsusle formed by filtreration is called
filtrate
what segments of the nephron loop transport salts?
thick
the glomerulus id composed of which capillaries
fenestrated
motor fibers of the renal plexus are branches of….
sympathetic NS
glomerular filtration
the process in which water and solutes from blood plasma pass from capillaries to the glomerulus into the capscular space of the nephron
filtration pressure ( in glomerulus) is determined by…
blood hydrostatic
colloid osmotic
glomeruluar filtration is blood filtered to form…
what affects the filtration coefficient
which has the highest hydrostatic pressure?
capillaries in glomeruli
Colloid osmotic pressure is about…
32 mm Hg
glomerular filtrate is most similar to
blood plasma
within the renal capsule, the COP is a pressure drawing fluid into what?
glomerular capillaries
dehydration can happen when…
GFR is too high
in the tubuloglomerular feedback mechanism, what is adjusted?
glomerular filtration
myogenic mechanism
the smooth muscle contracts when it stretches
Renin
converts angiotensinogen to angiotensin I
the sympathetic NS and adrenal apinephrine cause ___ of the afferent arterioles, and reduce the glomerular filtration rate
vasoconstriction
the myogenic mechanism maintains glomerular blood flow and therefore GFR by relaxing and constricting the ….
afferent arteriole
what activates the renin- angiotensin mechanism
decreased blood pressure
Macula densa
is a patch sensory cell on one side of the nephron loop that triggers tubuloglomerular feedback
the region of the nephron is adapted for reabsorption, as seen in its length and prominent microvili?
PCT
Tubular reabsorption referes to the movemnt of fluid and soluted where?
from the tubular fluid into the blood
angiotensin II stimulates the adrenal cortex to secret ___
aldosterone
during reabsorption from the PCT, water can carry dissolved substances by what proces?/
solvent drag
the antiport transports sodium into the cells of the PCT while pumping hydrogen out. What hormone activates this process?
aldosterone
what route passes through the cytoplasm and out of the base epithelial cells?
transcellular route
PCT…
reabsorbs 655%
most of the uric acid and none of the creatinine
what are the junctions between epithelial cells in the PCT?
tight junctions
pct is at a constant rate called…
obligatory water reabsorption
list the wastes removed from blood by tubular secretion:
bile
ureal
ammonia
list of solutes that are reabsorbed from nephron loop:
sodium
potassium
chloride
regulating hormones reabsorbed by the DCT?
natriuretic peptides
antodiuretic hormone
adldosterone
how is morphine removed from the blood?
tubular secretion
which renal tubule segments are influenced by aldosterone
collecting ducts
ascending limb of nephron loop
DCT
the kidneys help regulate acid base balance through the tubular secretion of
hydrogen and bicarbonate ions
what organ secretes natriautic peptides?
the heart
the primary function of the distal convoluted tubue and collecting duct is
the reabsorption of water and salts
antidiuretic hormone is secreted in response to…
dehydration
what is the role of collecting ducts
adjust the concentration of urine
countercurrent multiplier mechanism
returns salts to deeo renal medullary tissue
recaptures salts
osomolarity is ___ in the renal medulla than the ECF of the cortex
higher
what acts like a countercurrent exchanger
vasa recta
countercurrent exchange
blood flows in the opposite direction in adjacent parallel capillaries
polyuria or diuresis
excessive output of urine
normal pH for urine
4.5-8.2
what symptoms are seen with diabetes mellitus
glycosuria
dehydration
polyuria
the salts in the medullary ECF where transported from which limb of the nephron loop
ascending
what is a urine output of less than 500 mL called?
oliguria
which is the muscular sac on the floor of the pelvic cavity, inf to the perioneum and posterior to the pubic symphysis
bladder
conveys urine from the bladder out of the body
uretha
filling of the bladder stimulates stretch receptors that trigger what?
microurition