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Exam One
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Nucleus
contains most of the DNA in eukaryotic cell
Ribosomes
complexes made of ribosomal RNA and protien, use info from DNA to make protiens in two locations
Nuclear envelope
double membrane lipid bilayer surrounding nucleus
Nuclear pores
regulate entry/exit of molecules from the nucleus
Nucleolus
in nucleus, site of ribosomal RNA (rRNA) synthesis
Free ribosomes
protiens built in cytosol
Bound ribosomes
made on the outside of the endoplasmic reticulum or the nuclear envelope
Endomembrane system
regulates protien traffic and does metabolic functions, made of: nuclear envelope, endoplasmic reticulum, golgi apparatus, lysosomes, vacuoles, plasma membrane
Endoplasmic reticulum
over half of membrane in most eukaryotic cells, continous with nuclear envelope, two distinct regions: smooth ER and rough ER
Smooth ER (SER)
lacks ribosomes, sythesizes lipids, detoxifies drugs and poisons, stores calcium ions
Rough ER (RER)
surface studded with ribosomes that secrete glycoprotiens, distributes transport vesicles, membrane factory for cell
Golgi apparatus
flattened membranous sacs (cisternae), shipping and recieving center, modifies products of the ER, makes certain macromolecules
Lysosome
digestive compartments, fuses with food vacule to digest contents, can perfom autophagy
Autophagy
recycles cell’s own organelles and macromolecules
Vacuoles
diverse maintenence compartments, from ER and golgi apparatus
Mitochondria
sites for cellular respiration, powerhouse of the cell, inner membrane creates two compartments: intermembrane space and mitochondrial mix
Endosymbiont theory
ancestor or eukaryotes engulfed oxygen-using nonphotosynthetic prokaryotic cell, evolved into mitochondria
Cristae
outer and inner layer of mitochondria folded into cristae, large surface area for synthesis of ATP
Peroxisomes
oxidation, specialized metabolic compartments, have enzymes that remove hydrogen atoms and transfer them to oxygen, forms hydrogen peroxide
Cytoskeleton
network of fibers extending through cytoplasm, organizes and achors, composed of three types of molecular structures: microtubules, microfilaments, intermediate filaments
Microtubules
thickest of cytoskeleton components, shape cell, guides organelle movement, seperates chromosomes during division
Microfilaments
twisted double chain of actin, support cell shape, form a cortex just inside plasma membrane
Myosin
in microfilaments that function in cellular motility have this protien in addition to actin
Intermediate filaments
more permanant cytoskeleton fixtures, support cell shape and fix organelles in place
Extracellular matrix
made up of glycoprotiens (like collagen, proteoglycans, fibronectin), can regulate cell behavior by communication through integrins, can influence activity of genes in nucleus
Integrins
transmembrane receptors
Cell junctions
three types: tight junctions, desmosomes, gap junctions
Tight junctions
membranes of cells press together, prevents leakage of extracellular fluid
Desmosomes
anchoring junctions, fasten cells together into sheets
Gap junctions
communicating junctions, provide cytoplasmic channels between adjacent cells