compounding
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nonsterile, sterile and hazardous
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37 Terms
Nonsterile compounding USP chapter
795
Sterile compounding USP chapter
797
Hazardous compounding USP chapter
800
Compounding is primarily used to
avoid an excipient, add a flavor, prepare a non-commercially available product
Which graduate is the most accurate?
Graduated cyclinder
When should graduates never be used
measuring volume < 20% of capacity
Which product equipment is best for measuring small volumes?
Syringes
Which product equipment is best for measuring viscous liquids?
Syringes
Which motar and pestles are stain resistant?
Glass and porcelain
Which mortar and pestle is best for mixing dry crystals, hard powders, and pulverizing tablets
Wedgewood
Which mortar and pestle is preferred for sticky/gummy substances and blending powders?
Porcelain
Which mortar and pestle is best for products that contain dye or are oily?
Glass
Water activity (Aw) for aqueous compounds
0.6 or higher
Water activity (Aw) for nonaqueous compounds
less than 0.6
BUD for aqueous dosage forms without preservatives
14 days refrigerated
BUD for aqueous dosage forms with preservatives
35 days
BUD for nonaqueous oral liquid dosage forms
90 days
BUD for nonaqueous oral liquid dosage forms
180 days
IV bag/container with a volume < 100 mL
SVP
IV bag/container with a volume > 100 mL
LVP
The anteroom for hazardous drug compounding must be at what ISO Rating?
ISO 7
What air pressure should buffer rooms for hazardous drug compounding have?
Negative
How many air changes per hour (ACPH) is required for ISO 7?
30 ACPH
How many air changes per hour (ACPH) is required for ISO 7?
20 ACPH