overview of viral infectious life cycle

viral infectious life-cycle

1. entry- adsorption/attachment

2. uncoating

3. - 6. replication of DNA

7. assembly

8. exit and release

step 1 of viral infectious life cycle

Entry: peplomers + host cell receptor bind together to facilitate virus entry into host cell. Very specific to cell type

step 2 of viral infectious life cycle

Uncoating the viral DNA

Takes place in host cell cytoplasm

steps 3-6 of viral infectious life cycle

replication of DNA

goes through early transcription, early translation, new viral DNA produced, late translation

early transcription of viral DNA in replication

dna enters into host cell nucleus, viral DNA is transcribed to mRNA

early translation of viral DNA in replication

mRNA to protein for new virus particles

late translation of viral DNA replication

completion of virus capsid proteins

step 7 of viral infectious life cycle (assembly)

virions are produced

steps of assembly of new virus (step 7 of viral infectious life cycle)

1. assembly of new virus nucleocapsid

2. Some proteins are covered with host and viral proteins to become enveloped.

3. Some proteins are non-enveloped and accumulate in the cell.

step 8 of viral infectious life cycle

exit and release of completed virus particle

happens by budding or cell lysis.