Chapter 1: intro to biotechnology

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52 Terms

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Definition of biotechnology

Use of living organisms and biological systems to develop or modify products

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3 traditional biotechnology products

Cheese, bread, yogurt

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2 examples of modern biotechnology products

Therapeutic drugs, enzymes in laundry detergents

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When did modern biotechnology industry begain?

1982

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When did early humans begin selectively breeding plants and livestock?

8000 BC

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When was wine invented

4000 BC

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Who developed brewing and cheesemaking?

Sumerians

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What was the first antibiotic used? Which culture? When?

moldy soybean, Chinese, 500 BC

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Who developed smallpox vaccine? when

Edward Jenner, 1796

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Who discovered proteins?

Jons Jakob

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When was the origin of species published?

1859

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When was pasteurization first developed?

1861

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When did Mendel establish principles of genetics?

1865

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Who developed the first rabies vaccine? when

Paster,1885

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When did term “biotechnology” first appear n print?

1919

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Who desovered penicillin? Year?

Alexzander Flemming, 1928

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Who discovered DNA as carrier of genetics information

Oswald avery

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When was double helix of DNA discovered

1953

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When was Mrna discoverd

1961

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When was gene first completely synthsized

1971

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When was recombinant insulin produced? what company?

1973, Stanley Cohen and Herbert boyer develop

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When was DNA fingerprinting first used?

1984

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When were first genetically modified tobassco plant grown?

1986

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When was first human genome project landcaed

1990

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What was first cloned mammal? what year?

Sheep, 1997

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When was golden rice discovered?

1999

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When was first human genome completed

2003

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When was first HPV vaccine approved?

2003

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When was 1st self-replicating bacterial cell created?

2010

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When was CRISPR-CAS9 used for gene editing?

2012

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When were mRNA vaccines first used?

2021

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What are the different sectors in biotechnology

biological research, healthcare, agriculture, manufacturing

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What are the key techniques in biotechnology

molecular biology, cell biology, genetic engineering

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What is the ethical consideration in biotechnology

“Can we does not equal should we” Ethics= safety long term imacg

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What are tools in biotechnology?

Whole cells. DNA, RNA, proteins

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2 key instruments in biotechnology

Spectrophotometers, PCR machines

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Chromatography

sorting

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Whats gene transfer?

delivery system

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What is protein purification?

final product

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What is a spectrophotometer

Quantify DNA, proteins via light

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Whats a PCR

Amplify DNA→ used in forensics diagnostic cloning

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Key concepts behind using biotechnology in national defense

Life sciences, healthcare, agriculture, forensics, national defense

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Which company was founding biotechnology company, What was their first product?

National defense, biosurvilllen

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Difference between biotech and pharmaceutical industry?

biotech companies use living organisms and biological processes to create products (like vaccines and biologics), while pharmaceutical companies traditionally focus on synthesizing and manufacturing chemical-based drugs

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who key users of biotechonology

life sciences, healthcare, agriculture,forensics,national defense

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What is genomics?

study of entire genome

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What is proteomics?

Study of all proteins in organism

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What is precision medicine?

targeted therapies based on genetic profiles

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what happens during the drug discovery phase of drug development?

in vivo in vitro of lab animals

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what happens during phase 1 clinical trails?

tens of volunteers safety

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what happens during phase 2 clinical trails?

100s of volunteers effectiveness

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what happens during phase 3 clinical trails?

1000 of volunteers confirm