ACE Inhibitors Pharmacology Review

Vocabulary flashcards covering drug class, indications, mechanism of action, trade/generic names, side effects, contraindications, and nursing considerations for ACE inhibitors.

ACE Inhibitors (ACE-i)

A drug class representing Angiotensin converting enzyme inhibitors used primarily for hypertension and post-myocardial infarction care.

“-pril”

The common generic name suffix identifying angiotensin converting enzyme inhibitors (ACE-i).

Lisinopril

A generic ACE inhibitor associated with the trade name Zestril.

Captopril

A generic ACE inhibitor associated with the trade name Capoten.

ACE-i Mechanism of Action (MOA)

Blocks the conversion of angiotensin I to II.

ACE-i Indications

Clinical indications for ACE inhibitor administration, specifically Post MI and HTN.

ACE-i Route / Administration

The route of administration for ACE inhibitors, which is PO.

ACE-i Adverse Effects

Adverse effects including dizziness/fatigue, angioedema, hyperkalemia, dry cough, and hypotension.

ACE-i Black Box Warning (BBW)

Black box warning regarding pregnancy category C for the 1st trimester and category D for the 2nd/3rd trimesters.

ACE-i Precautions / Contraindications

Conditions listed under precautions/contraindications: liver disease, hypovolemia, hyperkalemia, pregnant/lactating, and HTN.

ACE-i Important Labs & Therapeutic Ranges

Monitoring requirements including K+ monitoring, Na NONE, respiratory assessment, and pregnancy assessment.

BP Assessment Rule (Nursing Consideration)

Nursing consideration to assess BP before administering, ensuring it is no less than $100\,\text{mmHg}$.

Position Changes Teaching (Nursing Consideration)

Patient teaching instruction to make no sudden position changes.

Salt Substitutes Consideration

Dietary guidance for patients taking ACE inhibitors specifying no salt substitutes.