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nosocomial
hospital accquired
what percent of mechanically ventilated patients develop pneumonia?
9-27%
What is the objective of infection control procedures?
eliminate the sources
create barriers to transmission
monitor the effectiveness of control
3 elements present to spread infection
source, route, host
when is someone most susceptible host?
when endorphins are low (stress, anger)
examples of sources
people, contaminated equipment, medications, catheters, tubes, lines
what is the origin of most nosocomial infections?
improper hand washing
3 major routes of transmission
contact
droplet
airborne
what is contact direct
body surface to body surface contact. pathogen transferred from person to person
what is indirect contact?
most frequent
occurs between host and inanimate object
examples of indirect contact
clothing, eating utensils, drinking glass, respiratory equipment, toys, inadequately processed equipment
examples of contact pathogens
hiv
std
hepatitis a,b,c
c diff
staphylococcus
polio
example of droplet pathogens
influenza
rubella
adenovirus
strep
pertussis
menigitis
SARS
covid
RSV
airborne
spread of contaminated dust particles or evaporated water droplets
size of droplet nuclei
less than 5um
examples of airborne
common cold, legionellosis, tb, fungal infections, measles, chickenpox, influenza, pertussis
what precautions should be implemented for covid?
contact and droplet
common vehicle
pathogens transmitted by contaminated food, water, medication
vector borne
animal or insect transfers the pathogen to the host
who is more susceptible for being a host?
immunocompromised, diabetics, obesity, copd, smokers, elderly, lines, drains, airways, surgical incisions
colonization
the presence of microorganisms w/o causing symptoms, disease, or detectable immune response
antiseptic
chemical agent applied to living tissue to kill microbes
pasteurization
the use of heat at a temp sufficient to inactivate pathogenic organisms in liquid (less heat than needed for sterilization)
sterilization
the complete killing or removal of all living organisms from a location or material
are there graduations in sterility?
no
iodophors
combination of iodine and a solubilizing agent or carrier the resulting complex provides a sustained release reservoir of iodine and releases small amounts of free iodine in aqueous solutions
critical items
high risk of infection if such an item is contaminated with any microorganism including bacterial spores
examples of critical items
cardiac and urinary items, implants, arthroscopes, laparoscopes, surgical instruments
if a object is heat sensitive what would it be treated with?
ethylene oxide, hydrogen peroxide, of liquid chemical sterilant
semi critical items
contact mucous membranes or nonintact skin
examples of semi critical
rt and anaesthia equipment
endoscopes
esophageal manometry probes
methods of sterilization
heat, radiation, chemical methods
dry heat
simplest method, expose the item to naked flame
only to items that will be damaged to moist
common temp time for dry heat
170 for 60 min
160 for 120 min
150 for 150 mins
moist heat
basic principle of steam sterilization as accomplished in autoclave
4 parameters of sterilization
steam
pressure
temperature
time
UV light
limited sterilization power because of poor penetration into most materials
ionizing radiation
typically by cobalt 60 gamma rays, is a low temp sterilization method
Ethylene Oxide (ETO)
colorless gas flammable and explosive
4 parameters that influence effectiveness of ETO sterilization
Gas Concentration (450-1200)
Temp (37-63)
relative humidity (40-80%)
exposure time (1-6 hrs)
what factors influence the activity of disinfectants
proportional to temp
time
range of action
may be inactivated by: dirt, organic matter, proteins, blood, mucus