Chapter 4- Nucleic Acids and an RNA World

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Ribonucleotides

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use uracil (U), while deoxyribonucleotides use thymine (T)

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G C

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Watson and Crick had discovered complementary base pairing between the A- T and bases.

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25 Terms

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Ribonucleotides

use uracil (U), while deoxyribonucleotides use thymine (T)

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G C

Watson and Crick had discovered complementary base pairing between the A- T and bases.

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Nucleic acids

are polymers, just as proteins are polymers.

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bridge

The formed by the phosphate group is called a phosphodiester linkage- also frequently referred to as a phosphodiester bond.

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DNAs secondary structure

consists of two anti parallel strands twisted into a double helix.

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guanine

The purines are adenine (A) and (G)

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Evolution

: Random changes in the nucleic acids would lead to the synthesis of different proteins and ribozymes.

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Replication

: Proteins and ribozymes would be processing information stored in nucleic acids for the synthesis of more proteins.

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pyrimidines

are cytosine (C), uracil (U), and thymine (T)

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Ribonucleotides

The monomers of ribonucleic acid (RNA) are referred to as

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chemical reaction

To catalyze a(n) , substrates must be brought together in an environment that will promote the reaction.

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DNA

By bombarding with X- rays and analyzing how it scattered the radiation, Rosalind Franklin and Maurice Wilkins had calculated the distances between groups of atoms in the molecule.

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hydrophobic interactions

The double helix is shaped and stabilized by hydrogen bonding between the complementary base pairs, , and van der Waals interactions.

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pyrimidine base thymine

The does not exist in RNA.

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monomers of deoxyribonucleic acid

The (DNA) are called deoxyribonucleotides.

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sugar phosphate

The sugar in the backbone of RNA is ribose, not deoxyribose as in DNA.

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Information

: Proteins and ribozymes would be processing stored in nucleic acids for the synthesis of more proteins.

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three dimensional nature of ribozymes

The is vital to their catalytic activity.

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Nucleic acids

are made up of monomers called nucleotides.

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Information

Proteins and ribozymes would be processing information stored in nucleic acids for the synthesis of more proteins

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Replication

Proteins and ribozymes would be processing information stored in nucleic acids for the synthesis of more proteins

22
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Evolution

Random changes in the nucleic acids would lead to the synthesis of different proteins and ribozymes

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Purines

are adenine (A) and guanine (G).

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Phosphodiester linkage

The bridge formed by the phosphate group is called a

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Base stacking

which results from van der Waals interactions between the tightly packed adjacent bases.