Chapter 4- Nucleic Acids and an RNA World

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Ribonucleotides

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1

Ribonucleotides

________ use uracil (U), while deoxyribonucleotides use thymine (T)

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2

G C

Watson and Crick had discovered complementary base pairing between the A- T and ________ bases.

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3

Nucleic acids

________ are polymers, just as proteins are polymers.

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4

bridge

The ________ formed by the phosphate group is called a phosphodiester linkage- also frequently referred to as a phosphodiester bond.

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5

DNAs secondary structure

________ consists of two anti parallel strands twisted into a double helix.

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guanine

The purines are adenine (A) and ________ (G)

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7

Evolution

________: Random changes in the nucleic acids would lead to the synthesis of different proteins and ribozymes.

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Replication

________: Proteins and ribozymes would be processing information stored in nucleic acids for the synthesis of more proteins.

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9

pyrimidines

are cytosine (C), uracil (U), and thymine (T)

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10

Ribonucleotides

The monomers of ribonucleic acid (RNA) are referred to as

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11

chemical reaction

To catalyze a(n) ________, substrates must be brought together in an environment that will promote the reaction.

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12

DNA

By bombarding ________ with X- rays and analyzing how it scattered the radiation, Rosalind Franklin and Maurice Wilkins had calculated the distances between groups of atoms in the molecule.

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13

hydrophobic interactions

The double helix is shaped and stabilized by hydrogen bonding between the complementary base pairs, ________, and van der Waals interactions.

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14

pyrimidine base thymine

The ________ does not exist in RNA.

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15

monomers of deoxyribonucleic acid

The ________ (DNA) are called deoxyribonucleotides.

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16

sugar phosphate

The sugar in the ________ backbone of RNA is ribose, not deoxyribose as in DNA.

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17

Information

________: Proteins and ribozymes would be processing ________ stored in nucleic acids for the synthesis of more proteins.

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18

three dimensional nature of ribozymes

The ________ is vital to their catalytic activity.

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19

Nucleic acids

________ are made up of monomers called nucleotides.

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20

Information

Proteins and ribozymes would be processing information stored in nucleic acids for the synthesis of more proteins

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21

Replication

Proteins and ribozymes would be processing information stored in nucleic acids for the synthesis of more proteins

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22

Evolution

Random changes in the nucleic acids would lead to the synthesis of different proteins and ribozymes

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23

Purines

are adenine (A) and guanine (G).

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24

Phosphodiester linkage

The bridge formed by the phosphate group is called a

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25

Base stacking

which results from van der Waals interactions between the tightly packed adjacent bases.

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