Comprehensive Guide to Coagulation Testing and Hemostasis in Veterinary Medicine

Why are automated coagulation tests preferred over manual tests?

They reduce variability associated with manual tests.

What can alter coagulation test results?

A low platelet count.

What are the three traditional coagulation pathways?

Intrinsic, extrinsic, and common pathways.

What supplies are needed for the buccal mucosa bleeding time test?

Spring-loaded lancet, blotting paper, stopwatch, tourniquet, and a sedated or anesthetized patient.

What indicates prolonged bleeding in the buccal mucosa bleeding time test?

Platelet dysfunction, deficiencies in von Willebrand factor, or thrombocytopenia.

What is the normal range for activated clotting time?

60 to 90 seconds.

What is the Lee-White method used for?

Whole blood clotting time measurement.

What can prolonged prothrombin time indicate?

Severe liver disease, DIC, deficiencies of coagulation factors, or vitamin K deficiency.

What does the clot retraction test evaluate?

Platelet number and function, as well as intrinsic and extrinsic pathways.

How is fibrinogen concentration determined manually?

By measuring total solids in two hematocrit tubes before and after incubation.

What does PIVKA stand for and what does it indicate?

Proteins Induced by Vitamin K Absence; indicates vitamin K deficiency.

What are D-Dimer and fibrin degradation products used to evaluate?

Tertiary hemostasis or fibrinolysis.

What factors can affect coagulation factor assays?

Hereditary or acquired conditions.

What does the thromboelastograph measure?

Initial clot formation, strength of the clot, and breakdown time.

What is a common effect of patient excitement during sample collection?

Increased platelet count and activation.

What is the significance of using a Vacutainer or Monovette for blood collection?

It ensures the proper ratio of anticoagulant to blood.