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Emphysema is defined as:
Destruction of the alveolar walls w/o fibrosis
Approximately how many Americans are affected by COPD?
24 Million
The mechanism of airway obstruction in COPD include:
Inflammation and Obstruction of small airway, loss of elasticity, active bronchospasm
Where does COPD rank among the leading causes of death in the U.S.A
Third
Approximately how many individuals died in the U.S.A in 2008
145,000
What is the leading risk factor for the development of COPD
Cigarette smoking
What % of all cases of COPD is caused by Alpha1-Antitrypsin Deficiency
2-3%
What is the critical AAT level below which lung elastin is attacked and broken down
57 mg/Dl
Which airways are most susceptible to airway obstruction in patients with COPD
Small
Which of the following signs associated with COPD is considered a late manifestation
Frequent coughing