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What are the two main divisions of the nervous system?
CNS and PNS
What is the central nervous system comprised of?
Brain and spinal cord
What is the peripheral nervous system comprised of?
Peripheral nerves and ganglia
What is the process of neurons?
Conduct electrical signals, release chemical signals, and integrate neurone activity
How do neurons conduct electrical signals?
Through action potentials
How do neurons release chemical signals?
Through neurotransmitters
How do neurons integrate neuronal activity?
Through association neurons
What are the two functions of the nervous system?
Control movement and detect external stimuli
How does the nervous system control movement?
Motor neurons
How does the nervous system detect external stimuli?
Sensory neurons
What defines a neuron?
A basic functional unit of the nervous system
What makes up a neuron?
A cell body, dendrites, and an axon
What is the purpose of dendrites?
to receive information from sensory receptors
What is the purpose of an axon?
to deliver electrical signals from the cell body to another neuron or effector organ
What neuron is used in dendrites to receive signals?
Sensory neuron
Where does integration take place?
Dendrites and cell body
Where is the action potential initiated?
Axon hillock
Where is the impulse conducted?
The axon to ending dendrites to neurotransmitters (NT)
Where are electrical impulses converted to chemical signals?
The synapse
What direction does action potential take place in?
Unidirectional
Sensory neurons (afferent) carry information from the
PNS to the CNS
Association neurons (interneurons) are found
entirely within the CNS
Motor neurons (efferent) carry information
out of the CNS
What are the two types of motor (efferent) neurons?
Somatic neurons and autonomic neurons
What do somatic neurons have control over?
Skeletal muscles (voluntary)
What do autonomic neurons have control over?
Heart, brain, etc (involuntary)
What are the two process of autonomic neruons?
Sympathetic and parasympathetic
What do sympathetic neurons do?
Speed up (Fight or Flight)
What do parasympathetic neurons do?
Slow down (Rest or Digest)
Association neurons (interneurons) carry information
neuron to neuron
What are the four different types of neurons?
Pseudopolar, bipolar, multipolar, and anaxonic
What are the most common types of neurons found in the body?
Multipolar neurons
Anaxonic neurons have no obvious
axon
What are the supporting cells of the PNS?
Schwann cells and satellite cells
What are Schwann cells?
Myelinated sheaths around the axon
What is the function of Schwann cells?
Insulate and speed up signals
What are the supporting cells of the CNS?
Oligodenrties, microglia, astrocytes, and ependymal
What do oligodendrocytes do?
Produce myelin in CNS
What di microglia do?
Pick up debris
What do astrocytes do?
Regulate the environment of neurons
What do ependymal cells do?
Help keep the shape of the brain and spinal cord
How do supporting cells of the CNS and PNS differ?
Insulation
Where are astrocytes most abundant?
Within the CNS as glial cells
What do astrocytes take up from extracellular fluid to help assist with neuron activity?
K+
What is the blood brain barrier?
A barrier creating strict control about what goes in and out of plasma into brain.
What is able to move through the blood brain barrier?
Nonpolar molecules, polar molecules, organic molecules, antibodies, immune cells,
What neuron influence the structure and function of the blood brain barrier?
Astrocytes
What are the two neurons in the efferent pathway?
Preganglionic and Postganglionic
What is the function of the preganglioninc neuron?
To cause a synapse with the second organ, but not directly innervate the effector organ
What is the function of the postganglioninc neuron?
To cause a synapse with the target tissue by going to an effector organ
What defines dual innervation?
When the same muscles or glands use both the PSNS and SNS
What are the organs without dual innervation?
Adrenal medulla, arrestor pili muscle, sweat glands in skin, and blood vessels
How are autonomic nerves classified?
By the neurotransmitters released across the synapse
What are the two neurotransmitters released across the synapse?
Achytylcholine (ACh) and Norepinephrine (NE)
What type of neuron releases ACh?
Cholinergic neurons
What type of neuron releases NE?
Adrenergic neurons
What do cholinergic neurons do?
Slow things down
What do adrenergic neurons do?
Modify things
What is synesthesia?
percieving letters or number as colours
What is chromothesia?
hear music as colours
What is synaesthesia?
coloured sounds taste sweet
What is simple diffusion?
a process of diffusion that does NOT consume energy
What is active transport?
a process of diffusion that requires metabolic energy, ATP
How does the Na+/K+ ATPase work?
Transports Na+ out of the cell and K+ into the cell
The Na+/K+ transport acts as the start of the
electrochemical gradient
What do ions do for electrochemical impulses?
Help produce the impulses that transmit information
What is the resting membrane potential voltage?
-70 mV
Where does Na+ start during resting membrane potential?
Outside
Where does K+ start during resting membrane potential?
inside
What is the primary function of nerve cells?
Receive, conduct, and transmit signals
How does depolarization work?
Positive charges flow into the cell
What is the action potential voltage?
+30mV
How does saltatory conduction work?
When one Node of ranvier is depolarized, it causes Na to rush in and travel down to the next node of ranvier. Causes the Extracellular Na from the next node of ranvier to travel to the now opened node of ranvier.
Why is saltatory conduction faster?
Myelin insulates axon, helps to maintain depolarization in cell (jumps from node of ranvier to node of ranvier)
This spread of depolarization is faster than waiting for more sodium channels to open
What is the refractory period?
a period immediately following stimulation during which a nerve or muscle is unresponsive to further stimulation. Helps action potential go in one way.
Where are neurotransmitters stored?
Synaptic vesicles
Where are neurotransmitters released?
Synapse
Where do neurotransmitters bind?
Postsynaptic receptors
What is the direction of synapse?
Presynaptic to postsynaptic
What type of matter makes up the CNS?
Gray and white matter
What is gray matter?
Mostly neuron cell bodies and nonmyelinated fibers
Where is gray matter found?
Surface layer of cortex
What is white matter?
Myelinated axons
Where is white matter found?
Under the cortex and around the nucleus
What are the meninges of the brain/spinal cord?
Dura matter, arachnid matter, and Pia matter
What is myotonia?
Delayed muscle relaxation after contraction
What is myotonia caused by?
Cl- mutation
What are the two cushions of the cerebrospinal fluid?
Outer and inner fluid cushions
What is the outer cavity of the fluid cushion?
Superior sagittal sinus (SSS)
What is the inner cavity of the fluid cushion?
Subarachnoid Space (SAS)
Where is the Superior sagittal sinus (SSS)?
Under the dura matter
Where is the Subarachnoid Space (SAS)?
Between arachnoid and Pia matter
How do we know if we have upper motor neuron damage?
Reflex is exaggerate or slightly normal
How do we know if we have lower motor neuron damage?
Reflex is diminished
What are the three primary vesicles of the brain?
Prosencephalon (forebrain)
Mesencephalon (midbrain)
Rhombencephalon (hindbrain)
What are the five secondary vesicles of the brain?
Telencephalon
Diencephalon
Mesencephalon
Mesencephalon
Myelencephalon
What are the five sections of the cerebrum?
Frontal lobe, occipital lobe, parietal lobe, temporal lobe, and insula
How is the cerebrum internally connected?
The corpus callosum
How many spinal nerve pairs are there?
31
(8 cervical)
(12 thoracic)
(5 lumbar)
(5 sacral)
(1 coccygeal)
What is the function of the frontal lobe?
Motor control