Psychiatric Medications: SSRIs, SNRIs, Antipsychotics, Benzodiazepines

Citalopram-MOA, Pharm class, Brand name?

MOA: binds to serotonin transporter at the presynaptic cleft, blocking reuptake of serotonin; increases serotonin concentration in cleft

Pharm class: SSRI

Brand: CeleXA

Escitalopram oxalate-MOA, Pharm class, Brand name?

MOA: binds to serotonin transporter at the presynaptic cleft, blocking reuptake of serotonin; increases serotonin concentration in cleft

Class: SSRI

Brand: Lexapro

Fluoxetine-MOA, Pharm class, Brand name?

MOA: binds to serotonin transporter at the presynaptic cleft, blocking reuptake of serotonin; increases serotonin concentration in cleft

Class: SSRI

Brand: PROzac

Paroxetine-MOA, Pharm class, Brand name?

MOA: binds to serotonin transporter at the presynaptic cleft, blocking reuptake of serotonin; increases serotonin concentration in cleft

Class: SSRI

Brand: Paxil

Sertraline-MOA, Pharm class, Brand name?

MOA: binds to serotonin transporter at the presynaptic cleft, blocking reuptake of serotonin; increases serotonin concentration in cleft

Class: SSRI

Brand: Zoloft

Vortioxetine-MOA, Pharm class, Brand name?

MOA: binds to post-synaptic receptors and acts as an agonist on some and antagonist on others

Class: serotonin modulator/stimulator

Brand: Trintellix

Duloxetine-MOA, Pharm class, Brand name?

MOA; binds to serotonin and/or norepinephrine transporter at the presynaptic cleft blocking the reuptake of serotonin/norepinephrine; increases serotonin/norepinephrine concentration in cleft

Class: SNRI

Brand: Cymbalta

Venlafaxine-MOA, Pharm class, Brand name?

MOA: binds to serotonin and/or norepinephrine transporter at the presynaptic cleft blocking the reuptake of serotonin/norepinephrine; increases serotonin/norepinephrine concentration in cleft

Class: SNRI

Brand: Effexor XR

Trazodone-MOA, Pharm class, Brand name?

MOA: blocks reuptake of serotonin and blocks autoreceptor

Class: Serotonin reuptake inhibitor

Brand: Desyrel

Bupropion-MOA, Pharm class, Brand name?

MOA: binds to dopamine and/or norepinephrine transporter at the presynaptic cleft blocking the reuptake of dopamine/norepinephrine; increases dopamine/norepinephrine concentration in cleft

Class: Dopamine/norepinephrine reuptake inhibitor

Brand: Wellbutrin

Amitriptyline-MOA, Pharm class, Brand name?

MOA: binds to serotonin and/or norepinephrine transporter at the presynaptic cleft blocking the reuptake of serotonin/norepinephrine; increases serotonin/norepinephrine concentration in cleft

Class: TCA

Brand: Elavil

Nortriptyline-MOA, Pharm class, Brand name?

MOA: binds to serotonin and/or norepinephrine transporter at the presynaptic cleft blocking the reuptake of serotonin/norepinephrine; increases serotonin/norepinephrine concentration in cleft

Class: TCA

Brand: Pamelor

Temazepam-MOA, Pharm class, Brand name?

MOA: GABA agonist; binds to GABA receptor and allows greater chloride influx, hyperpolarizing (deactivating) the nerve/cell

Class: Benzodiazepine

Brand: Restoril

Alprazolam-MOA, Pharm class, Brand name?

MOA: GABA agonist; binds to GABA receptor and allows greater chloride influx, hyperpolarizing (deactivating) the nerve/cell

Class: Benzodiazepines

Brand: Xanax

Lorazepam-MOA, Pharm class, Brand name?

MOA: GABA agonist; binds to GABA receptor and allows greater chloride influx, hyperpolarizing (deactivating) the nerve/cell

Class: Benzodiazepines/antiseizure agent

Brand: Ativan

Clonazepam-MOA, Pharm class, Brand name?

MOA: GABA agonist; binds to GABA receptor and allows greater chloride influx, hyperpolarizing (deactivating) the nerve/cell

Class: Benzodiazepines/antiseizure agent

Brand: KlonoPIN

Diazepam-MOA, Pharm class, Brand name?

MOA: GABA agonist; binds to GABA receptor and allows greater chloride influx, hyperpolarizing (deactivating) the nerve/cell

Class: Benzodiazepines/antiseizure agent

Brand: Valium

Risperidone-MOA, Pharm class, Brand name?

MOA: antagonizing 5HT2A autoreceptor, leading to enhanced dopamine release

Class: 2nd gen (atypical) antipsychotic

Brand: RisperDAL

Ziprasidone-MOA, Pharm class, Brand name?

MOA: antagonizing 5HT2A autoreceptor, leading to enhanced dopamine release

Class: 2nd gen (atypical) antipsychotic

Brand: Geodon

Quetiapine-MOA, Pharm class, Brand name?

MOA: antagonizing 5HT2A autoreceptor, leading to enhanced dopamine release

Class: 2nd gen (atypical) antipsychotic

Brand: SEROquel

Aripiprazole-MOA, Pharm class, Brand name?

MOA: antagonizing 5HT2A autoreceptor, leading to enhanced dopamine release

Class: 2nd gen (atypical) antipsychotic

Brand: Abilify

Olanzapine-MOA, Pharm class, Brand name?

MOA: antagonizing 5HT2A autoreceptor, leading to enhanced dopamine release

Class: 2nd gen (atypical) antipsychotic

Brand: ZyPREXA

Buspirone-MOA, Pharm class, Brand name?

MOA: unknown, believed to bind serotonin receptors and possibly dopamine receptors

Class: antianxiety misc.

Brand: NONE

Mirtazapine-MOA, Pharm class, Brand name?

MOA: blocks alpha-2 autoreceptor which increases norepinephrine and serotonin release

Class: Antidepressant, alpha-2 antagonist

Brand: Remeron

Haloperidol -MOA, Pharm class, Brand name?

MOA: Non selectively blocks postsynaptic dopaminergic D2 receptors in the brain

Class: 1st gen (typical) antipsychotic

Brand: Haldol