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Carrier of gases, nutrients, and waste products
Blood transports oxygen from the lungs to cells and carries carbon dioxide, nutrients, ions, and water from the digestive tract to cells, and waste products from cells to the kidneys for elimination.
Clot formation
Clotting proteins in the blood help stem blood loss when a blood vessel is injured.
Transport of processed molecules
Most substances produced in one part of the body are transported in the blood to another part.
Protection against foreign substances
Antibodies in the blood help protect the body from pathogens.
Transport of regulatory molecules
Various hormones and enzymes that regulate body processes are carried from one part of the body to another within the blood.
Maintenance of body temperature
Blood transports warm blood from the inside to the surface of the body, where heat is released.
pH and osmosis regulation
Albumin in the blood acts as a buffer and helps regulate the pH of the blood, as well as contributes to the osmotic pressure to keep water in the bloodstream.
Managing blood supply
Variations in heart contraction match blood flow to changing metabolic needs.
Producing blood pressure
Heart contractions produce blood pressure for blood flow through vessels.
Securing one-way blood flow
Heart valves ensure one-way blood flow through the heart and vessels.
Transmitting blood
The heart separates pulmonary and systemic circulations, ensuring oxygenated blood flow to tissues.
Anatomy of the heart
The cardiovascular system is like a muscular pump with valves and plumbing tubes.
Heart structure and functions
The heart is a small, strong organ located in the mediastinum.
Layers of the heart
The heart has three layers - epicardium, myocardium, and endocardium.
Chambers of the heart
The heart has four chambers - two atria and two ventricles.
Associated great vessels
Superior and inferior vena cava, pulmonary arteries, pulmonary veins, and aorta.
Heart valves
The heart has four valves - atrioventricular valves and semilunar valves.
Cardiac circulation vessels
Coronary arteries and cardiac veins supply and drain the myocardium.
Blood vessels
Arteries, arterioles, capillaries, venules, and veins form the vascular system.
Tunics
Blood vessel walls have three tunics - intima, media, and externa.
Physiology of the heart
The heart continuously pumps blood through the body.
Intrinsic conduction system of the heart
Spontaneous contractions of cardiac muscle cells give rhythm to the heart.
Cardiac cycle and heart sounds
Atria and ventricles contract and relax in a coordinated cycle.
Cardiac output
Amount of blood pumped out by each side of the heart in one minute.
Physiology of circulation
Efficiency of the circulatory system can be assessed through arterial blood and blood pressure measurements.
Cardiovascular vital signs
Arterial pulse, pulse rate, pressure points, blood pressure, and peripheral resistance.
Factors modifying basic heart rate
Autonomic nervous system activity, age, gender, exercise, and body temperature influence heart rate.
Renal factors
The kidneys regulate arterial blood pressure by adjusting blood volume through water excretion in urine.
Temperature
Cold causes vasoconstriction, while heat causes vasodilation.
Chemicals
Epinephrine increases heart rate and blood pressure, nicotine causes vasoconstriction, alcohol and histamine cause vasodilation and decreased blood pressure.
Diet
A low-salt, low-saturated fat, and low-cholesterol diet helps prevent hypertension.
Blood circulation through the heart
The right and left sides of the heart work together for smooth blood circulation.
Entrance to the heart
Blood enters the heart through the inferior and superior vena cava into the right atrium.
Atrial contraction
Blood flows from the right atrium to the right ventricle during atrial contraction through the tricuspid valve.
Closure of the tricuspid valve
The tricuspid valve shuts to prevent blood backflow into the atria during ventricle contraction.
Ventricle contraction
Blood leaves the heart through the pulmonic valve, into the pulmonary artery, and to the lungs for oxygenation.
Oxygen-rich blood circulates
Oxygen-rich blood from the lungs enters the left atrium through the pulmonary vein.
Opening of the mitral valve
Blood flows from the left atrium to the left ventricle through the open mitral valve during atrial contraction.
Prevention of backflow
The mitral valve shuts to prevent blood backflow into the atrium during ventricle contraction.
Blood flow to systemic circulation
Blood leaves the heart through the aortic valve, into the aorta, and to the body.
Capillary exchange of gases and nutrients
Substances move to and from body cells based on concentration gradients.
Capillary network
Capillaries form a network among cells, allowing substances to enter or leave cells easily.
Routes of capillary exchange
Substances can diffuse through lipid-soluble plasma membranes or pass through vesicles via endocytosis or exocytosis.
Intercellular clefts
Limited passage of fluid and small solutes occurs through intercellular clefts in capillaries.
Fenestrated capillaries
Fenestrated capillaries allow free passage of small solutes and fluid, found where absorption or filtration occurs.
Age-related physiological changes in the cardiovascular system
The heart's capacity for work decreases with age, and changes in arteries can negatively affect blood supply.