pathology immunity

Innate and acquired immunity ? Components ?

Who does NK cells recognize?

What are its receptors?

Receptors present on Pattern recognition receptors.?

TLR activates what and kills what?

CLR kills what?

NLR kills what?

RLR kills what?

Types of adaptive immunity?

Remember anitgen presenting cells classification and who they express and members?

What is mhc? Located on which chromosome? Differentiate mhc 1 and mhc 2?

Antigen binding cleft?

Presents antigen to?

Class III mhc does what?

HLA B27

HLA DQ2 DQ8

HLA DR 2

HLA DR3

HLA DR4

T cell

Formation?

Maturation?

Lymphnode?

Markers (6) remember as much as you can.

B cell

Formation?

Maturation?

Lymphnode?

Markers (6) remember as much as you can.

C3b is used for?

oBsonization

CD 3

CD 4

CD 8

CD 19

21

CD79a CD79b

What is isotype switching?

T cell has two types , what are they?

What does th1 th2 th17 do?

What does CD8 do?

Anaphylaxis and anaphylactoid?

Types of hypersensitivity?

Explain type I

How many phase and what happens?

Type II and Type V hypersensitivity

My Blood Group is Rh positive.?

Type III ?

M S H A R P ?

Type IV ? IL involved?

Which type of lepra reaction is formed?

Autograft ?

Isograft?

Xenograft?

Allograft?

HLA matching in organs?

Bone marrow

Kidney

Cornea

Heart

Liver

Lung

HLA matching , minimum how many genes should match.? Which gene is the most important?

Duration?

Hyperacute

Acute

Chronic

GVHD

Amyloidosis?

What is seen in

Xray crystallography / infrared spectroscopy?

EM?

Stain used?

Polarizing microscopy ?

AL

AA

A beta2m

AA

ATTR

ATTR

Abeta

ACal

AIAPP

Lardecous spleen and sago spleen

Best sites of biopsy for amyloidosis?

SOAPBRAINMD??

SHIPD?

Malar rash vs sarcoidosis rash?

DiGeorge Syndrome? Aka?

Defect and risk of infection in Hyper IgM syndrome?

Hyper IgE syndrome aka ?

Defect?

WAS?

What is low?

Which gene?

Triad?

Ataxia telangiectasia?