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When do you begin induction therapy?
Right after organ transplant
How does Basiliximab work in induction therapy
Tells T-lymphocytes to chill
SEs for Basiliximab?
Pretty much anything you can think of!
These 6 classes of meds are all example of what kind of therapy? •Calcineurin inhibitors
•Costimulation blockers
•Mammalian target of rapamycin inhibitors
•Purine antimetabolites
•Inosine monophosphate dehydrogenase inhibitors
•Corticosteroids
Maintenance therapy
Calcineuron basic way they work:
*FYI plentiful side effects
Stop T cells from proliferating, these are needed for B cells to also work.
•Costimulation blockers basic way they work
Same as Calcineuron, stop T cells from proliferating
•Mammalian target of rapamycin inhibitors basic way they work
stop T cells from dividing.
•Purine antimetabolites main use is for:
Kidney transplant!
•Inosine monophosphate dehydrogenase inhibitors mainly used for:
Heart, kidney, and liver transplants
What are corticosteroids used for in transplant rejection?
Acute rejection of transplant
What are toxoid vaccines?
Inactivated toxin stimulate defense on toxin
What are conjugate vaccines?
Like the name hints at, they are conjugated to something else that will force the body to have a reaction.
Recombinant vaccine
Vaccine that has an antigen that needs to grow in another host cell such as yeast.
mRNA vaccines
synthetic mRNA that tells body to make spike protein we want to fight. Sounds counterintuitive, people didn’t like the idea when it came to vaccinating against COVID.
Live Attenuated Vaccines
