Absolute Facts Drugs/Pathogens

Enterococcus faecalis DOC

Penicillin

Staphylococcus aureus DOC

Penicillinase-resistant beta lactams (MSSA), vancomycin for MRSA

Staphylococcus saprophyticus DOC

TMP-SMX

Streptococcus pneumoniae DOC

Usually susceptible to beta lactams

Streptococcus agalactiae (Group B strep) DOC

beta-lactam

Streptococcus pyogenes (Group A strep) DOC

beta-lactam

Streptococcus viridans group DOC

beta-lactam

Clostridium tetani DOC

anti-tetanus toxin

Aspergillus spp DOC

Antifungal azoles

Candida albicans DOC

Skin or mucosal infections: nystatin, antifungal azoles. Candidemia: echinocandins

Candida krusei DOC

echinocandins

Zygomycetes (Mucor spp. / Rhizopus spp.) DOC

Surgical debridement, followed by IV amphotericin B OR antifungal azoles

Pneumocystis jiroveci DOC

TMP-SMX or pentamidine

Chromoblastomycosis or fungal mycetoma DOC

Surgical excision followed by prolonged antifungal azole

Sporothrix schenckii DOC

antifungal azoles or potassium iodide

Malassezia spp. DOC

antifungal azoles or pyrithione zinc or selenium sulfide

Epidermophyton floccosum DOC

antifungal azoles or allylamines (terbinafine) or tolnaftate or griseofulvin

Microsporum spp. DOC

antifungal azoles or allylamines (terbinafine) or tolnaftate or griseofulvin

Trichophyton spp. DOC

antifungal azoles or allylamines (terbinafine) or tolnaftate or griseofulvin

Cryptococcus neoformans, Cryptococcus gatti DOC

Non-meningeal infections: antifungal azoles Meningitis: Amphotericin B + 5-Flucytosine, then follow up with fluconazole.

Blastomyces dermitiditis DOC

antifungal azoles

Coccidiodes immitis DOC

antifungal azoles

Histoplasma capsulatum DOC

antifungal azoles

Paracoccidiodes spp. DOC

antifungal azoles