pKa, DNA, functional groups

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Last updated 5:50 AM on 9/21/26
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20 Terms

1
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adenine

2
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guanine

3
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cytosine

4
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uracil

5
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thymine

6
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pKa of COOH group on amino acid

2.2

7
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pKa of amino group on amino acid

9.4

8
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pKa of regular COOH

4.5

9
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pKa of regular amine

9

10
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pKa of tyrosine

10.5

  • when pH> pKa, phenol grp gets deprotonated (negative)


11
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pKa of cysteine

8.4

  • when pH>pKa, sulfhydryl grp gets deprotonated (negative)


12
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pKa of lysine

10.5

  • normally pos.; when pH> pKa, NH3+ gets deprotoated (neutral)


13
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pKa of arginine

12.5

  • normally pos.; when pH>pKa, guanidino grp gets deprotonated (neutral)


14
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pKa of histidine

6

  • normally pos.; when pH>pKa, imidazole grp gets deprotonated (neutral)


15
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pKa of aspartate

3.9

  • normally neg.; when pH<pKa, COO- grp gets protonated (neutral)


16
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pKa of glutamate

4.1

  • normally neg.; when pH<pKa, COO- grp gets protonated (neutral)


17
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thioester

18
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phosphate ester

19
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diphosphate ester

20
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phosphate diester