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what are the symptoms of disruptive mood dysregulation disorder? (2)
constant/severe irritability and anger
what is the age range for diagnosis of disruptive mood dysregulation disorder?
-ages ___ to ___
-onset before age ___
6
18
10
how often must temper tantrums occur in disruptive mood dysregulation disorder?
at least 3 times a week
in which settings must symptoms appear for diagnosis of disruptive mood dysregulation disorder?
at least two of the following: (3)
home
school
with peers
is disruptive mood dysregulation disorder more common in males or females?
males
is disruptive mood dysregulation disorder more common in children or adolescents?
children
what medications may be considered if symptoms resemble major depressive disorder in disruptive mood dysregulation disorder?
antidepressants
what medications may be used to address irritability in disruptive mood dysregulation disorder? (3)
antidepressants
risperidone
aripiprazole
what is persistent depressive disorder formerly known as?
dysthymia
how long must depression last for persistent depressive disorder diagnosis in adults?
at least 2 years
how long must depression last for persistent depressive disorder diagnosis in children/adolescents?
at least 1 year
what additional symptoms must be present in persistent depressive disorder (at least 2)? (6)
decreased appetite/overeating
insomnia/hypersomnia
low energy
poor self-esteem
difficulty thinking
hopelessness
what type of distress does persistent depressive disorder cause?
social and occupational distress
when does persistent depressive disorder usually onset?
teenage years
how do patients with persistent depressive disorder often describe their depression?
they have "always felt this way" and see depression as normal functioning
can people with persistent depressive disorder also have major depressive episodes?
yes
is persistent depressive disorder more common in men or women?
women
what is treatment for persistent depressive disorder? (2)
psychotherapy (CBT)
antidepressants (SSRIs, SNRIs, TCAs)
cluster of symptoms in the last week before menstruation interfering with work or social life
premenstrual dysphoric disorder
what are symptoms of premenstrual dysphoric disorder? (6)
mood swings
irritability
depression
anxiety
feeling overwhelmed
difficulty concentrating
what are physical symptoms of premenstrual dysphoric disorder? (7)
lack of energy
overeating
hypersomnia/insomnia
breast tenderness
aching
bloating
weight gain
when do symptoms of premenstrual dysphoric disorder decrease?
with the onset of menstruation
when do symptoms of premenstrual dysphoric disorder cease?
after menopause (may return with hormone replacement therapy)
what lifestyle treatments help premenstrual dysphoric disorder? (6)
aerobic exercise
complex carbs
sufficient sleep
acupuncture
light therapy
relaxation therapy
which SSRIs have FDA approval for premenstrual dysphoric disorder? (3)
fluoxetine
sertraline
paroxetine CR
what other medication may help bloating and weight gain in premenstrual dysphoric disorder?
diuretics
what is substance/medication-induced depressive disorder caused by?
prolonged use or withdrawal from drugs/alcohol
how long do symptoms of substance/medication-induced depressive disorder last?
longer than expected physiological effects, intoxication, or withdrawal
when do symptoms appear in substance/medication-induced depressive disorder?
within 1 month of use
how long do symptoms last after substance removal?
few days to several weeks
what cns depressants are associated with depression? (4)
alcohol
barbiturates
benzodiazepines
clonidine
what cns medications are associated with depression? (5)
amantadine
bromocriptine
levodopa
phenothiazines
phenytoin
what psychostimulants are associated with depression?
amphetamines
what neurological conditions are associated with depression? (7)
epilepsy
parkinson
multiple sclerosis
alzheimer
huntingtons
tbi
stroke
what infectious or inflammatory conditions are associated with depression? (2)
neurosyphilis
HIV
what cardiac disorders are associated with depression? (3)
ischemic heart disease
cardiac failure
cardiomyopathies
what endocrine disorders are associated with depression? (4)
hypothyroidism
diabetes
vitamin deficiencies
parathyroid disorders
what neuroendocrine conditions are commonly accompanied by depression? (2)
cushing disease
hypothyroidism
one of the most common psychiatric disorders characterized by persistently depressed mood for at least 2 weeks
major depressive disorder
how long may a depressive episode last in major depressive disorder?
5 to 6 months
what are the DSM-5 criteria for major depressive disorder (criterion A)?
-___ or more symptoms in ___ weeks
-with at least ___ mood or loss of ___/___
5
2
depressed
interest/pleasure
what are the 9 symptoms of major depressive disorder (criterion A)?
1 ___ mood
2 loss of ___/___
3 weight/appetite ___
4 ___/___
5 psychomotor agitation/___
6 fatigue/loss of ___
7 worthlessness/excessive ___
8 poor ___/indecisiveness
9 recurrent thoughts of ___ or ___
depressed
interest/pleasure
change
insomnia/hypersomnia
retardation
energy
guilt
concentration
death
suicide
what does criterion C for major depressive disorder state?
symptoms cause clinically significant distress or impairment
what does criterion D for major depressive disorder state?
not attributable to substance or medical condition
what is the dsm-5 diagnosis for seasonal affective disorder (sad)?
major depressive disorder with seasonal pattern
when do depressive symptoms usually occur in sad? (2)
fall
winter
when is full remission usually seen in sad?
spring
what is required for a diagnosis of sad?
-___ seasonal depressive episodes within ___ years
-no nonseasonal episodes
2
2
what symptoms are associated with sad? (4)
hypersomnia
overeating
weight gain
craving carbohydrates
who is more commonly affected by sad? (2)
women
ages 18-30
why is adolescent depression concerning? (3)
higher prevalence than adults
high recurrence
lifelong risk
what are the primary risk factors for depression? (7)
female gender
adverse childhood experiences
stressful life events
first-degree family history
neuroticism
other psychiatric disorders
chronic/disabling medical conditions
what neurotransmitters are mainly involved in depression? (2)
serotonin
norepinephrine
what functions does serotonin regulate? (3)
sleep
appetite
libido
what dysfunctions occur with serotonin deficits? (5)
sleep disturbance
appetite decrease
low sex drive
poor impulse control
irritability
what functions does norepinephrine regulate? (2)
attention
behavior
what results from norepinephrine deficiency or imbalance? (3)
apathy
reduced responsiveness
slowed psychomotor activity
what other neurotransmitter is implicated in depression?
glutamate
increases neuron information transmission
glutamate
how does stress contribute to depression? (2)
depletes neurotransmitters
reduces neurogenesis
what hormones are elevated in depression? (2)
cortisol
corticotrophin-releasing hormone
what does hyperactivity of the hypothalamic-pituitary-adrenal (hpa) axis indicate?
major depressive disorder
negativistic thoughts about death, dying, or suicide
suicidal ideation
what increases suicide risk in depression? (5)
hopelessness
substance use
recent loss/separation
past suicide attempts
acute suicidal ideation
what are the key symptoms in depression? (2)
depressed mood
anhedonia
what appearance changes occur in depression? (3)
shabby/unkept
lack of bathing
no self-care
what eye contact and posture changes may occur in depression? (4)
little/no eye contact
slumped posture
head low
shoulders forward
what is psychomotor retardation? (3)
extremely slow movements
decreased facial expression
fixed gaze
what is psychomotor agitation? (4)
pacing
nail biting
finger tapping
tension-relieving activity
what are vegetative signs of depression? (4)
alterations in eating
elimination
sleeping
sex
how does appetite change in depression? (2)
loss of appetite (weight loss)
overeating (weight gain)
what bowel changes are seen in depression? (2)
constipation with retardation
diarrhea with agitation/anxiety
what sleep disturbance is hallmark of depression? (3)
insomnia
frequent waking
reduced deep sleep
what early morning pattern is common in depression?
waking at 3-4 a.m. and staying awake
increased sleep as escape, rarely restful
hypersomnia
what happens to sexual interest in depression? (3)
declines
loss of libido
impotence in men
general emotional condition/state
mood
how long can moods last?
hours to days
what mood is seen in depression?
depressed mood lasting weeks
what are terms to describe mood?
euthymic, euphoric, angry, irritable, anxious, apathetic
what feelings are common in depression? (5)
worthlessness
guilt
helplessness
hopelessness
anger
inability to feel pleasure or happiness
anhedonia
outward representation of internal state
affect
how is affect described in depression?
congruent or incongruent with mood
how is speech in depression? (4)
slow
soft
monotone
lacking spontaneity
how are insight and judgment affected in depression? (3)
negatively
poor judgment
indecisiveness
what behaviors may younger children show with depression?
suddenly refuse to go to school
what behaviors may adolescents show with depression? (3)
substance use
sexual promiscuity
preoccupation with death or suicide
what is the first assessment guideline for depression?
always evaluate patient's risk of harm to self or others
what should a medical/neurological exam help determine in depression assessment?
if depression is primary or secondary to another disorder
what vegetative signs of depression interfere with adls? (5)
impaired hygiene
sleep
nutrition
constipation
sexual functioning
what is always the highest priority in depression care?
safety
what are the three phases of treatment and recovery for depression?
-___ (6-12 weeks)
-___ (4-9 months)
-___ (1 year or more)
acute
continuation
maintenance
reduce depressive symptoms and restore psychosocial/work function
acute phase
what may be required in the acute phase? (3)
hospitalization
medication
biological treatments
what is the goal of the continuation phase?
prevent relapse through pharmacotherapy, education, psychotherapy
what is the goal of the maintenance phase?
prevent further episodes, decide whether to continue or phase out medication
why can silence still be meaningful with depressed patients?
it shows genuine interest and support
what health teaching points are key in depression care? (6)
1 depression is beyond voluntary control
2 it can be managed with meds/lifestyle
3 recognize signs of relapse
4 understand role/side effects of meds
5 combine meds with psychotherapy
6 cope with stress of relationships
what basic self-care issues must be assessed? (5)
caloric intake
fluids
sleep
hygiene
grooming