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1) Some form of ORDER
2) Response to environment and the ability
to adapt...EVOLUTION
3) The capacity for energy processing and
regulation...METABOLISM
4) The capacity for growth, development
and reproduction...INFORMATION PROCESSING AND CONTROL
All living things display
The Biosphere
• Ecosystems
• Communities
• Populations
• Organisms
• Organs and Organ Systems
• Tissues
• Cells
• Organelles
• Molecules
Vertical Organization:
Prokaryotes
single cell organisms
phylogenetic trees
Organisms are classified relative to each
other in ____
Cells do work (chemical,
mechanical, transport)
• Cells pass on information
to their progeny about
how to do the same work
Cells do two things:
carbon
All living organisms consist of molecules
based on the element____
proteins, DNA, lipids, carbohydrates
Carbon forms large molecules
H, O, N, S, P
carbon bonds to
Organic chemistry is now based upon the
concept of MECHANISMS
– the study of carbon
containing molecules, regardless of their origin
Organic chemistry is now based upon the
concept of MECHANISMS
four, four
Carbon has ___ valence electrons
– Allows for the formation of ___ covalent bonds with a
variety of atoms
• Completes valance shell
– Makes large, complex molecules possible
carbon chains
Form the skeletons of most organic molecules
– Vary in length and shape
hydrocarbons
contain only carbon and hydrogen
isomers
molecules with the same molecular formula but
different structures and properties
structural, geometric, Enantiomers
three types of isomers
structural isomers
Differ in covalent arrangements of their atoms
geometric isomers
Have the same covalent partnerships, but they differ in their spatial
arrangements. arise from the inflexibility of double
bonds which prevent the free rotation of atoms around the bond axis.
• These differences can drastically affect the biological activity of organic
molecules
Enantiomers isomers
Molecules which are the mirror image of one another
functional groups
chemically reactive groups of atoms within an
organic molecule
– Replace hydrogens bound to carbon sk
Hydroxyl
– Carbonyl
– Carboxyl
– Amino
– Sulfhydryl
– Phosphate
Six functional groups
ATP
Important source of energy for cellular
processes
• Consists of an organic molecule called
adenosine attached to three inorganic
phosphate groups.
Carbohydrates
– Lipids
– Proteins
– Nucleic acids
Four main classes of large biological
molecules (macromolecules)
macromolecules
Large molecules (polymers) composed of
smaller molecules (monomers)
synthesis
condensation reactions (also called
dehydration reactions)
– water is removed from functional groups on
the monomers
• One monomer loses a hydroxyl group –OH while
the other loses a Hydrogen (H)
– Reactions require cellular enzymes and ATP
Polymer Breakdown
– Hydrolysis reaction
• Water is added
– OH added to one monomer
– H added to other monomer
– Example:
• Digestion
polymer, monomers
Each class of ____ is formed from a
specific set of _____
Monosaccharides
– Disaccharides
– Polysacchardies
three types of carbs
Monosaccharides
simplest sugars
– used for fuel
– combined into disaccharides and polysaccharides
(polymers) via condensation reactions
Disaccharides
consist of two monosaccharides
– joined by a glycosidic linkage
• Covalent bond formed between two
monosaccharides by a dehydration reaction
EX:
Malt sugar
–Lactose (milk sugar)
–Sucrose (table sugar)
Polysaccharides
Serve many roles in organisms
• Energy storage
– Starch (plants)
– Glycogen (animals)
• Building material for structures that protect the cell
Cellulose
Most abundant organic compound on Earth
» Plant cell wall
– Chitin
Used by arthropods to build their exoskeleton
lipids
Provide long term energy storage and structure
• Generally hydrophobic
• Consist of one glycerol and three fatty acid molecules
un/saturated fats
types of lipids
Saturated fatty acids
Have as many hydrogens bonded to their carbon as
possible
– Solid at room temp
– No double bonds and molecules are packed tightly
together
– Unsaturated fatty acids (mono and poly)
– They have one or more double bonds connecting their carbons,
and fewer hydrogens
– Liquid at room temp and molecules are not packed tightly
together.
Phospholipids
Only two fatty acids
• phosphate group instead of a third fatty acid
hydrophilic, hydrophobic
phospholipids consist of Consists of a ____“head” and
_____ “tails”
bilayers
In water, form ____ in cells to “shield”
hydrophobic end from water
Structural – cellular support
– Enzymatic - enzymes
– Defense - antibodies
– Receptor – response to some stimuli
– Transport – transmembrane proteins
types of proteins
protein
consists of one or more polypeptides
Polypeptides
=polymers of amino acids
Amino acids
– organic molecules possessing both carboxyl and
amino groups
– differ in their properties due to differing side chains
– 20 known amino acids
– linked by peptide bonds
• between the carboxyl group of the first amino acid and the amino group of the second amino acid
Primary
• Secondary
• Tertiary
• Quaternary structure
4 Levels of Protein Structure
– Arise when a protein consists of two or more
polypeptide chains
Primary structure:
the unique sequence of
amino acids in a polypeptide
Secondary structure:
folding or coiling of the
polypeptide into a repeating configuration (includes
the helix and the pleated sheet
Tertiary structure:
overall 3-D shape of a polypeptide.
Results from interactions between amino acids and side
chains
Quaternary structure:
overall protein structure that results
from the aggregation of two or more polypeptide subunits
Denaturation:
protein unravels and loses its
native conformation
nuclic acid
Store and transmit hereditary information
DNA and RNA
types of nucleic acid
DNA
Information storage
• Provides direction for it’s own replication.
• Directs RNA synthesis
• Through the activity of RNA, DNA directs protein synthesis
RNA
Information storage
• Provides direction for it’s own replication.
• Directs RNA synthesis
• Through the activity of RNA, DNA directs protein synthesis
polynucleotides
macromolecules that exist as polymers called
_____
– Made up of monomers called nucleotides
Nucleotide
consist of
• A nitrogenous base
– Form hydrogen bonds in a complementary fashion
• A pentose (5 carbon sugar)
• A phosphate group
DNA double helix
consists of two antiparallel
nucleotide strands