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Pathogens
disease causing agents
Non-pathogens
Unable to cause disease
Bacteria Example
tuberculosis
Protozoa
Animal like cell, often a parasite, Malaria
Fungi
Plant-like organisms, Ringworm
Rickettsiae
Parasites such as lice, fleas, and ticks
Viruses
Can't reproduce without a host, blood borne, major risk to health care workers, Hepatitis B & C, HIV
microorganism
prefer warm and wet environment
Chain of infection 1
Causative agent (pathogen)
Chain of infection 2
Reservoir (place where pathogen stays, ex. human body
Chain of infection 3
Portal of exit (way the pathogen escapes, Ex. urine, feces)
Chain of infection 4
Mode of Transmission
Mode of Transmission Direct
Person to person. Sexual Contact and touching contaminated hand
Mode of Transmission Indirect
Touching contaminated equipment, breathing droplets, insect bites
Chain of infection 5
Portal of Entry (way to enter a new host. Ex. respiratory tract, breaks in the skin
Chain of infection 6
Susceptible Host (anyone who can contract the disease, weak immune system, or impaired defense mechanisms are susceptible.)
Ending the Chain of Infection
Hand washing, antiseptics, disinfectants, sterilization, alcohol, betadine etc.
Fomite
a surface or an object commonly handled by multiple people
pathogenic Microorganisms
Causes disease in different ways (toxins, allergic reactions, attack & destroy cells) Antibiotics are ONLY effective against bacteria, not viruses.
Types of Infections Endogenous
Inside the body Ex. Tumors
Types of Infections Exogenous
Outside the Body, Ex. Trauma and electric shock
Types of Infections Nosocomial
Acquired in healthcare facilities Ex. staph infections and pneumonia
Types of Infections Opportunisitc
Infections that only affect the immunosuppressed (immune system not functioning) Ex. Kaposi's sarcoma
Types of Infections Generalized
Something that is affecting multiple systems at once ex. respiratory and cardiovascular systems
Types of Infections Localized
Affects one system at a time ex. Nervous system
Epidemic
A widespread outbreak of an infectious disease locally.
Pandemic
A widespread outbreak of an infectious disease globally.
Antibiotics
kill or remove bacteria
Antiseptics
aseptic or sterile technique we use on the skin
Disinfectants
chemicals or created substances that kill microbes
Aseptic
aseptic means to be free of infection-causing organisms or to use methods to prevent their introduction and transfer to a patient.
Sterile
Being sterile means being free from all microorganisms, such as germs and bacteria, and also refers to the inability to produce offspring.
Avian
Another Word for bird
Influenza
A contagious disease of the lungs
Domesticated Animals
Animals that live around humans
Contagious
Capable of transmitting disease
Pandemic
An infectious disease that affects people globally
Zoonotic
An infectious disease that can be passed from animals to humans
Supportive care
medical attention focused on providing comfort rather than curing an illness
Vector borne
Vector-borne diseases are infections transmitted to humans and other animals through the bite or feeding of infected arthropods, such as mosquitoes, ticks, fleas, and flies.
Rabies
Reservoir : Bats, raccoons, cats dogs
Agent : Virus
Transmission : Saliva of infected animals
Human Symptoms : Seizure, paralysis, fever, fear of water
Treatment : Vaccines can be effective if given immediately after exposure ; however if victim is not treated quickly, only supportive care is possible (often fatal)
West Nile
Reservoir : Birds
Agent : Virus
Transmission : Mosquito bites bird, picks up virus, and then bites human
Human Symptoms : Fever, flu like symptoms
Treatment : Supportive, usually clears in a few weeks in healthy individuals
Toxoplasmosis
Reservoir : Pigs, cats, rats, deer, sheep
Agent : A single-celled parasite called Toxoplasma gondii
Transmission : Touching infected cat feces, eating undercooked meat, drinking contaminated water
Human Symptoms : Flu like symptoms
Treatment : Medications if needed
Mad Cow disease
Also known as Creutzfeldt-Lakob Disease
Reservoir : Cattle
Agent : Prion
Transmission : Eating infected beef
Human Symptoms : Memory loss, emotional instability, weakness
Treatment : Supportive (usually fatal within one year)
Lyme Disease
Reservoir : Deer
Agent : Borrelia burgdorferi, a bacterium
Transmission : Black legged tick feeds on infected deer, picks up bacterium, and bites human
Human Symptoms : Rash, arthritis, fever, swollen lymph nodes, neurologic signs, heart problems
Treatment : Antibiotics can be used for successful treatment when caught early
Ringworm
Reservoir : Any surface contaminated with fungus
Agent : Several kinds of fungus
Transmission : Touching a contaminated surface, brushes or combs, cows, horses, and other animals
Human Symptoms : Rash shaped in a ring on the skin, including scalp, groin area and feet
Treatment : Medicated creams, keeping area clean and dry
Avian Flu
Reservoir : Birds (especially domestic poultry)
Agent : Virus
Transmission : Contact with infected poultry or environments
Human Symptoms : Flu-like symptoms (coughing fever, sore throat), pneumonia
Treatment : Seasonal flu medications
Avian Flu facts
The deadly flu pandemic of 1918 (the spanish flu) was a strain related to bird flu
Bird flu has reappeared in the past decade
Wild birds can spread the virus to domestic poultry flocks'
In the 1997 Hong Kong outbreak, every chicken was killed to prevent the spread to humans
This virus has the ability to infect young and healthy people unlike most flu viruses that primarily infect the elderly and young children
Swine Flu (H1N1)
Reservoir : Pigs
Agent : Virus
Transmission : Coughs, sneezes, droplets, touching infected surfaces
Human Symptoms : Flu-like symptoms, pneumonia, diarrhea, vomiting
Treatment : Antiviral medications
Swine Flu facts
Swine Flu is less deadly than Avian flu ; however, Swine Flu is much more contagious
It is also a descendent of the 1918 Spanish Flu
The H1N1 strand of Swine Flu was first discovered in 1976
This type of virus is normally seen in birds and pigs, but managed to mutate itself in order to be virulent in humans
Spanish Flu
A type of Avian flu
Death toll from the Spanish flu of 1918 was estimated to be 20-50 million worldwide
Over half a million people died in the U.S. from the Spanish flu
More people died from the Spanish flu than were killed in WW1
Infection Prevention
The best method to prevent the spread of infection in healthcare is hand hygiene.
Standard Precautions
are the basic infection control practices we use to prevent spread of infection (good hand washing and PPE as needed).
Contact Isolation
Wound infection or skin infection Prevent--Gowns and gloves
Airborne Isolation
Infection that travels through the air Ex. Measles or tuberculosis Prevent--Gown and mask
Droplet Isolation
Infection from droplets like water or other liquids. Prevent--glove, mask, and eye protection
Putting PPE On (Donning) Order
hand hygiene, gown, mask, eye protection, gloves (mask on before entering the room