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What are the major groups of microorganisms? (4 examples)
1. bacteria
2. algae
3. protozoa
4. viruses
What is a microorganism?
Living bodies that are not visible to the naked eye
What is the Germ Theory of Disease?
many diseases are caused by microbes
Who proved the germ theory of disease?
Robert Koch
What is an acid-fast stain?
Used to stain organisms that resist conventional staining
What is the cell wall made of?
peptidoglycan in bacteria
What are two characteristics of Gram + organisms?
1. Stain Purple
2. Thick peptidoglycan wall
What are three characteristics of Gram - organisms?
1. Stain Pink
2. Thin peptidoglycan wall
3. Has an outer membrane Lipid A
What are two structures that are important to cellular survival?
1. Ribosomes
2. Chromosomes
What are three differences between prokaryotic and eukaryotic cell structure?
1. Prokaryotic have capsule
2. Eukaryotic have membrane bound organelles
3. Prokaryotic do not have a nucleus
What microbes can you not see with a light microscope?
Viruses
What is metabolism?
sum of all chemical reactions in the body
What is anabolism?
building up molecules
What is catabolism?
breaking down molecules
What are three factors that influence microorganism growth?
1. Ph
2. Temp.
3. Water availability
What is the energy and carbon source for phototroph?
1. Energy Source: Sunlight
2. Carbon
What is the energy and carbon source for photo chemotroph?
1. Sunlight
2. Organic Compounds
What is the energy and carbon source for Chemolithrautotroph?
1. Inorganic
2. CO2
What is the energy and carbon source for Chemorgantroph?
1. Organic Compounds
2. Organic Compounds
What is a virus?
A non-living particle that infect cells and cause disease
What is an animal virus?
Virus that infects animals, based on route transmissions
What is a plant virus?
Infect plant through wound in plant cell wall
What is a bacteriaphage?
A virus that infects bacteria
What is a lytic virus?
Makes more viruses, release more , kills cells
What is the lysogenic cycle?
Does not kill cells
What is a latent virus?
an inactive virus
What is the purpose of aerobic respiration?
It uses oxygen to convert the chemical energy stored in organic molecules to ATP
What four things happen in aerobic respiration?
1. Glycolysis
2. Transition Step
3. TCA cycle
4. Electron Transport Chain
What is the difference between aerobic and anaerobic respiration?
Aerobic puts out more ATP, anerobic does not
What does an enzyme do
speeds up a chemical reaction
What is an enzyme made of?
amino acids
What is lag phase?
"flat" period of adjustment, enlargement; little growth
What is log phase?
exponential growth; makes antibiotics
What is the stationary phase?
Population stabilized
What is the death phase?
Viable cells decrease, death ensues
What is passive aquired immunity?
Occurs naturally during pregnancy
What is epidemology?
The study of the frequency and distribution of an illness or a disorder in a population.
What is drug resistance and how does it develop?
Adaptive response ends with tolerations, can be spontaneous mutations or Acquistion of plasmids transfer
What are the 5 mechanisms microbes can use for drug resistance?
1. Decreased permeability
2. Drug inactivation
3. Activation of drug pumps
4. Change in drug binding sites
5. Alternate metabolic pathway
What are three important aspects about the first line of defense?
1. Physical
2. Chemical
3. Genetic Components
What are four important aspects about the second line of defense?
1. Inflammatory
2. Interferons
3. Phagocytosis
4. Complement
What are three important aspects about the third line of defense?
1. Vaccination
2. Antibodies
3. Specific host defenses
What are B cells?
B-lymphocytes; they release antibodies into blood.
What cell types an B-Cells make?
1. Memory
2. Plasma
3. Antibodies
How do helper T cells activate B cells?
When it recognizes the antigen.
How are Cytotoxic T- cells activated?
activated by dendritic cells that have antigen
What is the difference between sterilization and disinfection?
Sterilization removes all, disinfection removes most germs
What do you three things need to be considered when choosing a method of microbial control?
1. Type of microbe
2. Risk of infection
3. Contamination extent
What is pasteurization? Is this a form of sterilization?
Brief heat treatment used to reduce organisms that cause food spoilage. No it is not sterilization
What are the symptoms?
effects experienced by patient
What are the signs?
effects that can be observed through examination
What has to happen in order to have an infection?
colonized organisms have parasitic relationship with hos
What is type 1 hypersensitivity?
IgE mediated
What is type 2 hypersensitivity?
cytotoxic
What type is 3 hypersensitivy?
Immune complex mediated
What is type 4 hypersensitivity?
cell mediated