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Flashcards for BIOL 141 Exam 3 Review
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Mitosis
Cell division resulting in two identical daughter cells.
Prophase
First stage of mitosis, chromosomes condense and become visible.
Metaphase
Chromosomes align along the metaphase plate.
Anaphase
Sister chromatids separate and move to opposite poles.
Telophase
Chromosomes arrive at the poles, and nuclear envelope reforms.
Interphase
The period of the cell cycle between cell divisions.
G1 phase
Cell grows and duplicates organelles.
S phase
DNA replication occurs.
G2 phase
Cell prepares for division.
Cytokinesis
Division of the cytoplasm to form two separate cells.
Karyotype
Visual representation of chromosomes.
Autosomal chromosome
Non-sex chromosome (1-22 in humans).
Homologous chromosome
Members of a chromosome pair, one from each parent.
Haploid
n (number of chromosomes in a gamete).
Diploid
2n (number of chromosomes in a somatic cell).
Somatic cell
Body cell.
Gamete
Sex cell (sperm or egg).
Daughter cell
Clone of mother cell produced by cell division.
Sister chromatid
Identical copies of a chromosome created during S phase.
Meiosis
Cell division that produces gametes (sex cells).
Crossing over
Exchange of genetic material between homologous chromosomes during prophase I of meiosis.
Independent assortment
Random alignment of homologous pairs during metaphase I of meiosis.
Nondisjunction
Failure of chromosomes to separate properly during anaphase I or II of meiosis.
Monosomy
Condition where there is one less chromosome than normal (n-1).
Trisomy
Condition where there is one extra chromosome than normal (1+n).
Down syndrome
Trisomy 21.
Turner syndrome
Monosomy of X chromosome.
Patau syndrome
Trisomy 13.
Jacobs syndrome
Trisomy of Y chromosome (XYY).
Allele
Options for a gene.
Genotype
The genetic makeup of an organism.
Phenotype
Physical characteristics of an organism.
Dominant allele
Allele that is expressed when present.
Recessive allele
Allele that is not expressed when a dominant allele is present.
Homozygous dominant
Two dominant alleles (e.g., DD).
Homozygous recessive
Two recessive alleles (e.g., rr).
Heterozygous
One dominant and one recessive allele (e.g., Dr).
Incomplete dominance
No allele is completely dominant, resulting in a mixed phenotype.
Codominance
Both alleles are dominant and both are expressed.
Epistasis
One gene overrides the expression of another gene.
Polymorphism
Three or more alleles for one gene.
Quantitative trait
The trait is determined by more than one gene.
Transformation
Taking foreign DNA by a cell, changing it’s genotype.
Transcription
Copying DNA into mRNA.
Translation
From mRNA to protein (ribosome).
Codon
Three nucleotides that code for a single amino acid.
RNA polymerase
Enzyme that transcribes DNA into mRNA.
mRNA
Messenger RNA; carries the genetic code from DNA to ribosomes.
tRNA
Transfer RNA; carries amino acids to the ribosome during translation.
Ribosome
Site of protein synthesis.
Spliceosome
Removes introns from pre-mRNA.
Promoter region
Region of DNA where RNA polymerase binds to initiate transcription.
Terminator region
Region of DNA that signals the end of transcription.
Anticodon
A sequence of three nucleotides in a tRNA molecule that corresponds to a codon in mRNA.
P site, A site, E site
Sites on the ribosome where tRNA binds during translation.