CNS & Muscle + Bone Drugs

Wellbutrin, Zyban

Generic: Bupropion | Class: Norepinephrine-dopamine reuptake inhibitor | Function: Modulate the activities of the neurotransmitters norepinephrine (NE), dopamine (DA) | Route: PO | Usage: Depression, Smoking cessation

Celexa

Generic: Citalopram | Class: Selective serotonin reuptake inhibitor (SSRI) | Function: Modulate the activity of the neurotransmitter serotonin (5-HT) | Route: PO | Usage: Depression, Anxiety, others

Lexapro

Generic: Escitalopram | Class: Selective serotonin reuptake inhibitor (SSRI) | Function: Modulate the activity of the neurotransmitter serotonin (5-HT) | Route: PO | Usage: Depression, Anxiety, others

Prozac, Sarafem

Generic: Fluoxetine | Class: Selective serotonin reuptake inhibitor (SSRI) | Function: Modulate the activity of the neurotransmitter serotonin (5-HT) | Route: PO | Usage: Depression, Anxiety, others

Paxil

Generic: Paroxetine | Class: Selective serotonin reuptake inhibitor (SSRI) | Function: Modulate the activity of the neurotransmitter serotonin (5-HT) | Route: PO | Usage: Depression, Anxiety, others

Zoloft

Generic: Sertraline | Class: Selective serotonin reuptake inhibitor (SSRI) | Function: Modulate the activity of the neurotransmitter serotonin (5-HT) | Route: PO | Usage: Depression, Anxiety, others

Pristiq

Generic: Desvenlafaxine | Class: Serotonin-norepinephrine reuptake inhibitor (SNRI) | Function: Modulate the activities of the neurotransmitters serotinin (5-HT), norepinephrine (NE) | Route: PO | Usage: Depression, Anxiety, Nerve Pain Management, others

Cymbalta

Generic: Duloxetine | Class: Serotonin-norepinephrine reuptake inhibitor (SNRI) | Function: Modulate the activities of the neurotransmitters serotinin (5-HT), norepinephrine (NE) | Route: PO | Usage: Depression, Anxiety, Nerve Pain Management, others

Effexor

Generic: Venlafaxine | Class: Serotonin-norepinephrine reuptake inhibitor (SNRI) | Function: Modulate the activities of the neurotransmitters serotinin (5-HT), norepinephrine (NE) | Route: PO | Usage: Depression, Anxiety, Nerve Pain Management, others

Elavil

Generic: Amitriptyline | Class: Tricyclic antidepressant (TCA) | Function: Modulate the activities of the neurotransmitters serotinin (5-HT), norepinephrine (NE), domapine (DA), acetylcholine (Ach) | Route: PO | Usage: Depression, Anxiety, Nerve Pain Management, insomnia, others

Silenor

Generic: Doxepin | Class: Tricyclic antidepressant (TCA) | Function: Modulate the activities of the neurotransmitters serotinin (5-HT), norepinephrine (NE), domapine (DA), acetylcholine (Ach) | Route: PO | Usage: Depression, Anxiety, Nerve Pain Management, Insomnia, others

Pamelor

Generic: Nortriptyline | Class: Tricyclic antidepressant (TCA) | Function: Modulate the activities of the neurotransmitters serotinin (5-HT), norepinephrine (NE), domapine (DA), acetylcholine (Ach) | Route: PO | Usage: Depression, Anxiety, Nerve Pain Management, others

Remeron

Generic: Mirtazapine | Class: Tetracyclic antidepressant | Function: Alter the activity of the neurotransmitter serotinin (5-HT) | Route: PO | Usage: Depression

Desyrel, Oleptro

Generic: Trazodone | Class: Serotonin antagonist + reuptake inhibitor | Function: Alter the activity of the neurotransmitter serotonin (5-HT) | Route: PO | Usage: Depression; insomnia

Strattera

Generic: Atomoxetine | Class: Norepinephrine reuptake inhibitor (ADHD) | Function: Alter the activity of norepinephrine (NE) | Route: PO | Usage: Reduce the symptoms of ADHD

Adderall, Mydayis

Generic: Amphetamine-Dextroamphetamine | Class: CNS stimulant | Function: Modulate the activities of the neurotransmitters dopamine (DA), norepinephrine (NE) | Route: PO | Usage: Reduce the symptoms of ADHD

Focalin

Generic: Dexmethylphenidate | Class: CNS stimulant | Function: Modulate the activities of the neurotransmitters dopamine (DA), norepinephrine (NE) | Route: PO | Usage: Reduce the symptoms of ADHD

Vyvanse

Generic: Lisdexamfetamine | Class: CNS stimulant | Function: Modulate the activities of the neurotransmitters dopamine (DA), norepinephrine (NE) | Route: PO | Usage: Reduce the symptoms of ADHD

Ritalin, Concerta, Metadate ER

Generic: Methylphenidate | Class: CNS stimulant | Function: Modulate the activities of the neurotransmitters dopamine (DA), norepinephrine (NE) | Route: PO | Usage: Reduce the symptoms of ADHD

Adipex-P, Lomaira

Generic: Phentermine | Class: CNS stimulant + anorexiant | Function: Modulate the activities of the neurotransmitters dopamine (DA), norepinephrine (NE), AND serotonin (5-HT) | Route: PO | Usage: Promote weight loss (in conjunction with appropriate diet)

Buspar

Generic: Buspirone | Class: Anti-anxiety agent | Function: Reduce the symptoms of anxiety (serotonin) | Route: PO | Usage: Anxiety

Xanax

Generic: Alprazolam | Class: Benzodiazepine | Function: Reduce the symptoms of anxiety (GABA) | Route: PO | Usage: Anxiety (Short-term only)

Klonopin

Generic: Clonazepam | Class: Benzodiazepine | Function: Reduce the symptoms of anxiety (GABA) | Route: PO | Usage: Anxiety (Short-term only)

Valium, Diastat, Valtoco

Generic: Diazepam | Class: Benzodiazepine | Function: Reduce the symptoms of anxiety (GABA) | Route: PO | Usage: Anxiety (Short-term only)

Ativan

Generic: Lorazepam | Class: Benzodiazepine | Function: Reduce the symptoms of anxiety; control seizure (GABA) | Route: PO | Usage: Anxiety (Short-term only)

Atarax, Vistaril

Generic: Hydroxyzine | Class: Histamin-1 (H1) antagonist | Function: Reduce the symptoms of anxiety, reduce insomnia (Histamine) | Route: PO | Usage: Anxiety, Insomnia

Haldol

Generic: Haloperidol | Class: Antipsychotic (1st generation) | Function: Dopamine receptor-2 blocker | Route: PO, IM | Usage: Reduce the symptoms of psychosis

Latuda

Generic: Lurasidone | Class: Antipsychotic (2nd generation, “atypical”) | Function: Dopamine receptor-2 blocker & Serotonin receptor-2 blocker (antagonist) | Route: PO | Usage: Reduce the symptoms of psychosis, bipolar disorder, or severe depression

Zyprexa

Generic: Olanzapine | Class: Antipsychotic (2nd generation, “atypical”) | Function: Dopamine receptor-2 blocker & Serotonin receptor-2 blocker (antagonist) | Route: PO | Usage: Reduce the symptoms of psychosis, bipolar disorder, or severe depression

Seroquel

Generic: Quetiapine | Class: Antipsychotic (2nd generation, “atypical”) | Function: Dopamine receptor-2 blocker & Serotonin receptor-2 blocker (antagonist) | Route: PO | Usage: Reduce the symptoms of psychosis, bipolar disorder, or severe depression; insomnia

Risperdal

Generic: Risperidone | Class: Antipsychotic (2nd generation, “atypical”) | Function: Dopamine receptor-2 blocker & Serotonin receptor-2 blocker (antagonist) | Route: PO | Usage: Reduce the symptoms of psychosis, bipolar disorder, or severe depression

Geodon

Generic: Ziprasidone | Class: Antipsychotic (2nd generation, “atypical”) | Function: Dopamine receptor-2 blocker & Serotonin receptor-2 blocker (antagonist) | Route: PO, IM | Usage: Reduce the symptoms of psychosis, bipolar disorder, or severe depression

Abilify

Generic: Aripiprazole | Class: Antipsychotic (2nd generation, “atypical”) | Function: Dopamine receptor-2 blocker & Serotonin receptor-2 blocker (antagonist) | Route: PO | Usage: Reduce the symptoms of psychosis, bipolar disorder, or severe depression

Lunesta

Generic: Eszopiclone | Class: Hypnotic (sleep) | Function: Reduce the symptoms of insomnia (promote sleep) by increasing GABA signaling activity | Route: PO | Usage: Insomnia

Ambien, Edluar, Intermezzo

Generic: Zolpidem | Class: Hypnotic (sleep) | Function: Reduce the symptoms of insomnia (promote sleep) by increasing GABA signaling activity | Route: PO | Usage: Insomnia

Restoril

Generic: Temazepam | Class: Benzodiazepine | Function: Reduce the symptoms of insomnia (promote sleep) by increasing GABA signaling activity | Route: PO | Usage: Insomnia, anxiety

Keppra, Elepsia XR, Roweepra, Spritam

Generic: Levetiracetam | Class: Anticonvulsant | Function: Alter release of several neurotransmitters | Route: PO, IV | Usage: Control epilepsy (Prevent seizure)

Depakote, Depakene

Generic: Divalproex sodium | Class: Anticonvulsant | Function: Alter GABA activity oi the neurons | Route: PO, IV | Usage: Control epilepsy (Prevent seizure) or reduce symptoms of Bipolar disorder

Neurontin, Gralise

Generic: Gabapentin | Class: Anticonvulsant | Function: Alter GABA activity in the neurons | Route: PO | Usage: Control epilepsy (Prevent seizure) or nerve pain (GABA)

Lyrica

Generic: Pregabalin | Class: Anticonvulsant | Function: Alter GABA activity in the neurons | Route: PO | Usage: Control epilepsy (Prevent seizure) or nerve pain (GABA)

Tegretol, Carbatrol, Epitol, Equetro

Generic: Carbamazepine | Class: Anticonvulsant | Function: Alter sodium channel activity in the neurons | Route: PO | Usage: Control epilepsy (Prevent seizure) or reduce symptoms of Bipolar disorder

Trileptal

Generic: Oxcarbazepine | Class: Anticonvulsant | Function: Alter sodium channel activity in the neurons | Route: PO | Usage: Control epilepsy (Prevent seizure)

Lamictal

Generic: Lamotrigine | Class: Anticonvulsant | Function: Alter sodium channel activity in the neurons | Route: PO | Usage: Control epilepsy (Prevent seizure) or reduce symptoms of Bipolar disorder

Dilantin, Phenytek

Generic: Phenytoin | Class: Anticonvulsant | Function: Alter sodium channel activity in the neurons | Route: PO, IV, PR | Usage: Control epilepsy (Prevent seizure)

Topamax, Qudexy XR, Trokendi XR

Generic: Topiramate | Class: Anticonvulsant | Function: Alter sodium channel activity AND GABA activity in the neurons | Route: PO | Usage: Control epilepsy (Prevent seizure)

Aricept

Generic: Donepezil | Class: Cholinesterase inhibitor | Function: Reduce the symptoms of Alzheimer’s Disease (by reducing Acetylcholine breakdown) | Route: PO | Usage: Alzeheimer’s disease (Dementia)

Namenda

Generic: Memantine | Class: NMDA receptor antagonist | Function: Reduce the symptoms of Alzheimer’s Disease (by reducing Acetylcholine breakdown) | Route: PO | Usage: Alzeheimer’s disease (Dementia)

Lithobid, Eskalith

Generic: Lithium carbonate | Class: Antimanic | Function: Reduce the symptoms of mania in bipolar patients | Route: PO | Usage: Bipolar disorder

Sinemet, Duopa, Rytary

Generic: Carbidopa-levodopa | Class: Anti-Parkinson’s agent | Function: Reduce the symptoms of Parkinson’s Disease (by enhancing Dopamine activity) | Route: PO | Usage: Parkinson’s disease (Movement disorder)

Mirapex

Generic: Pramipexole | Class: Anti-Parkinson’s agent; dopamine agonist | Function: Reduce the symptoms of Parkinson’s Disease (by mimicking Dopamine activity) | Route: PO | Usage: Parkinson’s disease (Movement disorder)

Requip

Generic: Ropinirole | Class: Anti-Parkinson’s agent; dopamine agonist | Function: Reduce the symptoms of Parkinson’s Disease (by mimicking Dopamine activity) | Route: PO | Usage: Parkinson’s disease (Movement disorder)

Chantix

Generic: Varenicline | Class: Partial nicotine receptor agonist | Function: Reduce the urge to nicotine (cigarette smoking) (by altering Dopamine activity) | Route: PO | Usage: Smoking cessation

Imitrex, Onzetra Xsail, Tosymra

Generic: Sumatriptan | Class: Serotonin receptor 1A agonist | Function: Activate serotonin 1A receptor to reduce the symptoms of migraine | Route: PO, Nasal, SC | Usage: Migraine headache

Lumigan

Generic: Bimatoprost | Class: Prostaglandin analog | Function: Increase outflow of aqueous humor | Route: OPTH | Usage: Reduce the symptoms and complications of glaucoma in eyes

Xalatan, Xelpros

Generic: Latanoprost | Class: Prostaglandin analog | Function: Increase outflow of aqueous humor | Route: OPTH | Usage: Reduce the symptoms and complications of glaucoma in eyes

Travatan Z

Generic: Travoprost | Class: Prostaglandin analog | Function: Increase outflow of aqueous humor | Route: OPTH | Usage: Reduce the symptoms and complications of glaucoma in eyes

Timoptic, Betimol, Istalol

Generic: Timolol | Class: β1/β2-blocker | Function: Reduce the production of aqueous humor | Route: OPTH | Usage: Reduce the symptoms and complications of glaucoma in eyes

AlphaganParkin P

Generic: Brimonidine | Class: α2-agonist (opthalmic) | Function: Reduce the production of aqueous humor AND increase the outflow of aqueous humor | Route: OPTH | Usage: Reduce the symptoms and complications of glaucoma in eyes

Cosopt

Generic: Dorzolamide-timolol | Class: Combination carbonic anhydrase inhibitor + β-blocker | Function: Reduce the production of aqueous humor AND increase the outflow of aqueous humor | Route: OPTH | Usage: Reduce the symptoms and complications of glaucoma in eyes

Fosamax, Binosto

Generic: Alendronate | Class: Bisphosphonate (osteoporosis) | Function: Promote osteoblast activity, inhibit osteoclast activity (bone formation) | Route: PO | Usage: Osteoporosis & lower blood calcium

Boniva

Generic: Ibandronate | Class: Bisphosphonate (osteoporosis) | Function: Promote osteoblast activity, inhibit osteoclast activity (bone formation) | Route: PO, IV | Usage: Osteoporosis & lower blood calcium

Actonel, Atelvia

Generic: Risedronate | Class: Bisphosphonate (osteoporosis) | Function: Promote osteoblast activity, inhibit osteoclast activity (bone formation) | Route: PO | Usage: Osteoporosis & lower blood calcium

Evista

Generic: Raloxifene | Class: Selective estrogen receptor modulator (SERM) | Function: Promote estrogen-like activity in bone formation | Route: PO | Usage: Osteoporosis

Nolvadex, Soltamox

Generic: Tamoxifen | Class: Selective estrogen receptor modulator (SERM) | Function: Promote estrogen-like activity in bone formation AND INHIBIT estrogen activities in preventing breast cancer | Route: PO | Usage: Osteoporosis; prevent breast cancer

Rocaltrol

Generic: Calcitriol | Class: Vitamin D analog | Function: Promote bone formation; increased calcium in blood | Route: PO | Usage: Osteoporosis

Delta D3

Generic: Cholecalciferol | Class: Vitamin D analog | Function: Promote bone formation; increased calcium in blood | Route: PO | Usage: Osteoporosis

Drisdol, Calciferol

Generic: Ergocalciferol | Class: Vitamin D analog | Function: Promote bone formation; increased calcium in blood | Route: PO | Usage: Osteoporosis

Tylenol

Generic: Acetaminophen | Class: Analgesics and antipyretics (lower fever) | Function: Inhibit the synthesis of prostaglandins in the CNS ONLY | Route: PO, PR, IV | Usage: Pain control; reduce fever

Celebrex

Generic: Celecoxib | Class: COX-2 inhibitor (also an NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation

Voltaren, Zorvolex

Generic: Diclofenac | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation

Lodine

Generic: Etodolac | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation

Mobic, Vivlodex

Generic: Meloxicam | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation

Relafen

Generic: Nabumetone | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation

Motrin, Advil (OTC & RX)

Generic: Ibuprofen | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation; reduce symptoms of gout attack

Indocin, Tivorbex

Generic: Indomethacin | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation; reduce symptoms of gout attack

Naprosyn, Aleve (OTC & RX)

Generic: Naproxen | Class: Non-steroidal anti-inflammatory drug (NSAID) | Function: Inhibit the production of the inflammatory prostaglandins | Route: PO | Usage: Pain control and anti-inflammation; reduce symptoms of gout attack

Ultram, ConZip

Generic: Tramadol | Class: Opioid analgesic | Function: Activate the mu opioid activity to reduce pain | Route: PO | Usage: Moderate pain control

Ultracet

Generic: Tramadol-acetaminophen | Class: Opioid analgesic combination | Function: Activate the mu opioid activity to reduce pain; reduce pain perception | Route: PO | Usage: Moderate pain control

Duragesic, Subsys, Ionsys

Generic: Fentanyl | Class: Opioid analgesic | Function: Activate the mu opioid activity to reduce pain | Route: IV, DERM, SL | Usage: Severe pain control

Norco, Vicodin, Lortab

Generic: Hydrocodone-acetaminophen | Class: Opioid analgesic combination | Function: Activate the mu opioid activity to reduce pain; reduce pain perception | Route: PO | Usage: Severe pain control

Dilaudid, Exalgo

Generic: Hydromorphone | Class: Opioid analgesic | Function: Activate the mu opioid activity to reduce pain | Route: PO | Usage: Severe pain control

Dolophine, Methadose

Generic: Methadone | Class: Opioid analgesic | Function: Activate the mu opioid activity to reduce pain | Route: PO | Usage: Severe pain control

MS Contin, Kadian, Roxanol

Generic: Morphine | Class: Opioid analgesic | Function: Activate the mu opioid activity to reduce pain | Route: PO | Usage: Severe pain control

Oxycontin, Roxicodone, Xtampza ER

Generic: Oxycodone | Class: Opioid analgesic | Function: Activate the mu opioid activity to reduce pain | Route: PO | Usage: Severe pain control

Suboxone, Zubsolv, Bunavail

Generic: Buprenorphine-Naloxone | Class: Opioid agonist/antagonist | Function: PARTIALLY activate the mu opioid activity to reduce pain; naloxone to prevent abuse | Route: PO | Usage: Moderate pain control or opioid abstinence

Lioresal, Gablofen, Ozobax

Generic: Baclofen | Class: Skeletal muscle relaxant | Function: Alter GABA-B receptor activity | Route: PO | Usage: Relax muscle to reduce muscle-related discomfort and/or pain

Soma

Generic: Carisoprodol | Class: Skeletal muscle relaxant | Function: NOT well established | Route: PO | Usage: Relax muscle to reduce muscle-related discomfort and/or pain

Flexeril, Amrix, Fexmid

Generic: Cyclobenzaprine | Class: Skeletal muscle relaxant | Function: NOT well established | Route: PO | Usage: Relax muscle to reduce muscle-related discomfort and/or pain

Skelaxin

Generic: Metaxalone | Class: Skeletal muscle relaxant | Function: NOT well established | Route: PO | Usage: Relax muscle to reduce muscle-related discomfort and/or pain

Robaxin

Generic: Methocarbamol | Class: Skeletal muscle relaxant | Function: NOT well established | Route: PO | Usage: Relax muscle to reduce muscle-related discomfort and/or pain

Zanaflex

Generic: Tizanidine | Class: Skeletal muscle relaxant | Function: Alter Adrenergic alpha 2 receptor activity | Route: PO | Usage: Relax muscle to reduce muscle-related discomfort and/or pain

Colcrys, Mitigare, Gloperba

Generic: Colchicine | Class: Anti-gout agent | Function: Anti-inflammatory by multiple mechanisms | Route: PO | Usage: Reduce the symptoms of gout attack

Zyloprim, Aloprim

Generic: Allopurinol | Class: Xanthine oxidase inhibitor (gout) | Function: Reduce the production of uric acid, which causes gout | Route: PO | Usage: Prevent gout

Uloric

Generic: Febuxostat | Class: Xanthine oxidase inhibitor (gout) | Function: Reduce the production of uric acid, which causes gout | Route: PO | Usage: Prevent gout

Arimidex

Generic: Anastrazole | Class: Aromatase inhibitor | Function: Block estrogen production | Route: PO | Usage: Anti-estrogen to prevent breast cancer

Femara

Generic: Letrozole | Class: Aromatase inhibitor | Function: Block estrogen production | Route: PO | Usage: Anti-estrogen to prevent breast cancer

Robitussin AC, Cheratussin AC, Virtussin AC

Generic: Guaifenesin-codeine | Class: Combination antitussive + expectorant | Function: Reduce the cough-triggering effects and reduce phelm production | Route: PO | Usage: Reduce severe coughing and loosen mucus in lungs

Tessalon Perles

Generic: Benzonatate | Class: Antitussive | Function: Local anesthetics in the lungs | Route: PO | Usage: Reduce severe coughing

Lidoderm

Generic: Lidocaine | Class: Topical anesthetic | Function: Inhbit the generation and transmission of pain signals | Route: DERM, IM | Usage: Pain control

Cogentin

Generic: Benztropine | Class: Anticholinergic | Function: Reduce the dopamine-blocking effect from antipsychotics via blocking acetylcholine | Route: PO, IM, IV | Usage: Reduce antipsychotic-related movement problems