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1.1: Outline the features of the principal components of the digestive system
Mouth, Esophagus, Stomach, Small intestine, Large intestine, Pancreas, Liver, Gall bladder
Features of the mouth
Mechancial and chemical digestion (carbohydrates)
Salivary amylase
pH7
Features of esophagus
Peristalsis/peristaltic (involuntary muscle movement)
Features of the stomach
Rugae/lumen/mucous coating
Features of small intestine
Villi/microvilli (tiny little folds that sit within small intestine and can increase surface area and absorption of nutrients
Features of large intestine
Water balance/vitamin absorption
Features of pancreas
Production of enzymes
Pancreatic lipase/amylase/trypsin
Features of liver
Production of bile
Features of gall bladder
Storage of bile
1.2: State the typical pH values found throughout the digestive system (include location)
Mouth: 5.5 to 7.5
Stomach: 1.0 to less than 4.0
Small intestine: 6.0 to 8.0
BG Knowledge: Enzyme
Enzymes are proteins that act as biological catalysts by accelerating chemical reactions in our bodies
1.3: Describe the function of enzymes in the context of macronutrient digestion
Enzymes act as a biological catalyst, accelerating the rate that large molecules of food are broken down into smaller molecules (in order to facilitate their absorption by the body)
Reference macronutrient digestion
Each macronutrient (carbs, proteins, fats) requires a specialised enzyme to be broken down
this process involves a lock and key model
BG Knowledge: Digestive Enzymes
Enzymes in the alimentary canal that break down food so that that the organism can absorb it
1.4: Explain the need for enzymes in digestion
Aid in the breakdown of large molecules into smaller molecules to more soluble substances that get absorbed into the bloodstream
Increase the rate of digestion without disrupting body temperature (increase up to 37 degrees and then slows down)
Most enzymes only catalyse one specific reaction, making them specialised.
1.5: List the enzymes that are responsible for the digestion of carbohydrates, fats and proteins from the mouth to the small intestine - Carbohydrates
Carbs
Enzyme: Salivary amylsae, pancreatic amylase
Site: Oral cavity, small intestine
1.5: List the enzymes that are responsible for the digestion of carbohydrates, fats and proteins from the mouth to the small intestine - Fats
Fats
Enzyme: Pancreatic lipase, bile
Site: Small intestine
1.5: List the enzymes that are responsible for the digestion of carbohydrates, fats and proteins from the mouth to the small intestine - Proteins
Proteins
Enzymes: Pepsin, trypsin
Site: Stomach, small intestine
1.6: Describe the absorption of glucose, amino acids and fatty acids from the intestinal lumen to the capillary network - Glucose
Carbohydrates are absorbed as monosaccharides
Occurs via active transport where Glucose is transported into epithelial cells of villi
Glucose crosses the brush-border membrane and passes through the cytosol of the absorptive cell, crossing the basolateral membrane
Then enters capillary network
1.6: Describe the absorption of glucose, amino acids and fatty acids from the intestinal lumen to the capillary network - Amino Acids
Amino acids cross the brush-border membrane of intestinal cells
Pass through cytosol of absorptive cell and crosses basolateral membrane
Enter the capillary network that surrounds the intestine
1.6: Describe the absorption of glucose, amino acids and fatty acids from the intestinal lumen to the capillary network - Fatty Acids
Brush border found on the villi in the small intestine
Brush border creates a very large surface area for quicker absorption of fatty acids