120 rule

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Last updated 6:23 AM on 8/24/26
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4 Terms

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120 Rule in lung function assessment

A clinical guideline that states PaCO2 + PaO2 should equal greater than 120 mmHg, allowing clinicians to assess lung function quickly in room air (21% oxygen at sea level).

2
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Hypoventilation assessment using the 120 Rule

If PaCO2 = 60 mmHg and PaO2 = 85 mmHg, then PaCO2 + PaO2 = 145 mmHg, indicating the patient is suffering from hypoventilation only.

3
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Hypoxemia and admixture

If PaCO2 = 60 mmHg and PaO2 = 40 mmHg, PaCO2 + PaO2 = 100 mmHg, indicating the patient has both admixture and hypoventilation.

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Admixture without hypoventilation

If PaCO2 = 40 mmHg and PaO2 = 60 mmHg, PaCO2 + PaO2 = 100 mmHg, indicating the patient has admixture without hypoventilation.