hematopoiesis

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Last updated 2:19 PM on 9/29/24
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20 Terms

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Hematopoietic medications

Medications that increase the production of blood cells.

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Hematopoiesis

The process of blood cell production occurring primarily in the bone marrow.

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Erythrocytes

Red blood cells responsible for carrying oxygen in the blood.

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Leukocytes

White blood cells that are part of the immune system.

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Platelets

Small cell fragments that help in blood clotting, derived from megakaryocytes.

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Hematopoietic stem cells

Progenitor cells in the bone marrow that can differentiate into various blood cell types.

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Lymphoid progenitors

Cells that can develop into lymphoblasts and further differentiate into T-lymphocytes, B-lymphocytes, or natural killer cells.

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Myeloid progenitors

Cells that can differentiate into erythrocytes, megakaryocytes, or immune cells like monocytes and neutrophils.

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Growth factors

Specific chemicals that signal hematopoietic stem cells to differentiate into mature blood cells.

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GM-CSF

Granulocyte macrophage colony stimulating factor that stimulates myeloid progenitors and speeds up maturation of immune cells.

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G-CSF

Granulocyte colony stimulating factor that specifically induces myeloblasts to mature into neutrophils.

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Thrombopoietin

A glycoprotein that stimulates the differentiation of hematopoietic stem cells into megakaryocytes and platelets.

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Erythropoietin (EPO)

A hormone produced in the kidneys that stimulates the production of red blood cells.

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Sargramostim

A synthetic version of GM-CSF used to boost myeloid precursor production after bone marrow transplant.

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Filgrastim

A recombinant G-CSF used to correct neutropenia and increase neutrophil production.

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Romiplostim

A recombinant thrombopoietin used to stimulate platelet production in thrombocytopenia.

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Eltrombopag

A synthetic drug that acts as an agonist at the thrombopoietin receptor to stimulate megakaryocyte production.

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Epoetin

A recombinant erythropoietin used to treat anemia, especially in chronic renal failure.

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Bone marrow suppression

A condition where the bone marrow's ability to produce blood cells is reduced, often due to chemotherapy or radiation.

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Anemia

A condition characterized by a low red blood cell count, leading to fatigue and weakness.