Toxic Shock Syndrome (TSS)
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9 Terms
What bacterium causes toxic shock syndrome?
Staphylococcus aureus.
What toxin is most associated with TSS?
TSST-1 (Toxic Shock Syndrome Toxin-1).
How does TSST-1 cause disease?
It acts as a superantigen, causing massive cytokine release.
Is TSS caused primarily by bacterial invasion of tissues?
No. It is mainly caused by toxins entering the bloodstream.
What type of toxin is TSST-1?
A superantigen
What immune response is responsible for many TSS symptoms?
cytokine storm.
Do the bacteria usually spread throughout the body in TSS?
No. The toxins spread through the bloodstream.
What type of rash is characteristic of TSS?
A diffuse sunburn-like rash.
What happens to the skin about a week after symptoms begin?
It peels (desquamates).